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Lancet (London, England) May 1955
Topics: Adrenal Hyperplasia, Congenital; Adrenogenital Syndrome; Cortisone; Disorders of Sex Development; Estrogens
PubMed: 14368951
DOI: 10.1016/s0140-6736(55)91115-6 -
The Journal of Clinical Investigation Mar 1951
The effects of adrenocorticotropic hormone and cortisone in the adrenogenital syndrome associated with congenital adrenal hyperplasia: an attempt to explain and correct its disordered hormonal pattern.
Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adrenogenital Syndrome; Cortisone
PubMed: 14824274
DOI: 10.1172/JCI102438 -
Acta Paediatrica Belgica 1960
Topics: Adrenal Hyperplasia, Congenital; Adrenogenital Syndrome; Electrolysis; Electrolytes; Humans
PubMed: 13819533
DOI: No ID Found -
The Journal of Clinical Endocrinology... Apr 1954
Topics: Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Hyperplasia, Congenital; Adrenogenital Syndrome; Humans; Steroids
PubMed: 13152167
DOI: 10.1210/jcem-14-4-409 -
Deutsche Medizinische Wochenschrift... May 2008Information about the treatment of males with congenital adrenal hyperplasia (CAH) is scarce and there are no therapeutical guidelines. The aim of this review is to... (Review)
Review
Information about the treatment of males with congenital adrenal hyperplasia (CAH) is scarce and there are no therapeutical guidelines. The aim of this review is to provide a survey of the current data. An extensive literature research was performed in PubMed for relevant articles published in the last ten years. The aim in the treatment of adult male CAH patients is preservation of fertility, prevention of an addisonian crisis, blood pressure management, prevention of testicular adrenal rest tumors (TART), maintaining well-being and good quality of life, satisfactory sexual function and prevention of long-term side effects of gluco- and mineralocorticoid therapy. The change from paediatric to adult medicine should be handled in a transition outpatient clinic organized by paediatric and adult endocrinologists. Most studies have included only small numbers of patients. The steroid therapy is usually orientated on an individual basis; but, general guidelines are lacking. It is reported that fertility is often impaired and related to the occurrence of TART. Some of these tumors are responsive to altered glucocorticoid therapy. However, glucocorticoid-resistant TART have been described, and testis-sparing surgery seems to be a treatment option. A future system of regular follow-up visits and standardized therapy guidelines are essential to provide a better medical care and a higher quality of life for male patients with CAH.
Topics: Addison Disease; Adrenal Hyperplasia, Congenital; Adrenal Medulla; Adrenal Rest Tumor; Adrenogenital Syndrome; Adult; Continuity of Patient Care; Glucocorticoids; Humans; Hypertension; Infertility, Male; Male; Mineralocorticoids; Steroid 21-Hydroxylase; Testicular Neoplasms
PubMed: 18446680
DOI: 10.1055/s-2008-1075688 -
The Journal of Pediatrics Dec 1952
Topics: Adrenal Cortex; Adrenal Cortex Diseases; Adrenal Hyperplasia, Congenital; Adrenogenital Syndrome; Cortisone
PubMed: 13011706
DOI: 10.1016/s0022-3476(52)80306-3 -
Das Deutsche Gesundheitswesen Jun 1967
Topics: Adrenal Hyperplasia, Congenital; Female; Humans; Prednisone
PubMed: 5600015
DOI: No ID Found -
British Medical Journal Dec 1956
Topics: Adrenal Hyperplasia, Congenital; Adrenogenital Syndrome; Female; Humans; Steroids; Virilism
PubMed: 13374337
DOI: 10.1136/bmj.2.5005.1348 -
The American Journal of Nursing May 1967
Topics: Adrenal Hyperplasia, Congenital; Humans
PubMed: 5181621
DOI: No ID Found -
Southern Medical Journal Aug 1978A case of bilateral testicular tumors thought secondary to hyperplastic adrenal rest tissue in an adult with the adrenogenital syndrome is presented. The appropriate...
A case of bilateral testicular tumors thought secondary to hyperplastic adrenal rest tissue in an adult with the adrenogenital syndrome is presented. The appropriate endocrinologic diagnosis of 21-hydroxylase deficiency was made by extensive hormonal assay of serum and urine. Pathologic investigation suggested Leydig cell hyperplasia or tumor, but clinical and laboratory response to steroid therapy indicated elaboration of androgens from adrenal or adrenal rest sources. We believe initial medical therapy is justified in these particular cases.
Topics: Adrenal Hyperplasia, Congenital; Adult; Humans; Male; Testicular Neoplasms
PubMed: 684481
DOI: No ID Found