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Gynecologic Oncology Aug 2005To the best of our knowledge, pseudo-Meigs syndrome (PMS) has never been described in the setting of gliomatosis peritonei (GP), both arising from an ovarian teratoma.... (Review)
Review
To the best of our knowledge, pseudo-Meigs syndrome (PMS) has never been described in the setting of gliomatosis peritonei (GP), both arising from an ovarian teratoma. We present a case of ovarian teratoma with both these rare findings. The case is unique as it presents two rare manifestations of ovarian teratoma in the same patient; there are many cases in the literature where both these manifestations have been described in different patients. The case is also rare because lymph node involvement along with gliomatosis was found. We review the literature for these two rare complications of ovarian teratoma.
Topics: Adult; Female; Humans; Meigs Syndrome; Neuroglia; Ovarian Neoplasms; Peritoneal Neoplasms; Teratoma
PubMed: 15963555
DOI: 10.1016/j.ygyno.2005.03.048 -
Pediatric Blood & Cancer Nov 2015Meigs syndrome, the combination of benign ovarian tumor, ascites, and pleural effusion, is present in a small percentage of ovarian fibromas and is infrequently reported... (Review)
Review
Meigs syndrome, the combination of benign ovarian tumor, ascites, and pleural effusion, is present in a small percentage of ovarian fibromas and is infrequently reported in children. When associated with elevated CA-125 suspicion is raised for malignancy, often prompting aggressive surgical intervention. We present a case of childhood Meigs syndrome and review the relevant literature with emphasis on ovary preservation. Out of nine identified pediatric cases, one involved ovary sparing treatment and none recurred or progressed to malignancy. Our report highlights the importance of presurgical identification of Meigs syndrome in order to curtail salpingo-oophorectomy when feasible.
Topics: Adolescent; CA-125 Antigen; Female; Humans; Meigs Syndrome; Membrane Proteins; Organ Sparing Treatments; Ovary
PubMed: 26011288
DOI: 10.1002/pbc.25586 -
Gynecologic Oncology Apr 2004Pseudo-Meigs' syndrome is a syndrome that includes hydrothorax and/or ascites secondary to ovarian neoplasms other than benign primary tumors. Gastrointestinal... (Review)
Review
INTRODUCTION
Pseudo-Meigs' syndrome is a syndrome that includes hydrothorax and/or ascites secondary to ovarian neoplasms other than benign primary tumors. Gastrointestinal malignancies, including colorectal or gastric adenocarcinoma, are rare etiologies for this syndrome.
CASE REPORT
In this report, we present the case of a 49-year-old woman with metastatic colon cancer who acutely developed a massive pleural effusion and ascites coincident with a rapidly enlarging adnexal mass and a rising CA-125 level.
DISCUSSION
Seven cases of pseudo-Meigs' syndrome secondary to gastrointestinal primaries have been reported to date. This case highlights the difficulty in discerning the diagnosis of pseudo-Meigs' syndrome from that of disseminated colorectal cancer or a new primary ovarian neoplasm and the importance in making the distinction to initiate appropriate therapy.
Topics: Colorectal Neoplasms; Female; Humans; Meigs Syndrome; Middle Aged; Ovarian Neoplasms
PubMed: 15047245
DOI: 10.1016/j.ygyno.2003.12.025 -
American Journal of Obstetrics and... Nov 1948
Topics: Female; Humans; Meigs Syndrome
PubMed: 18888239
DOI: 10.1016/0002-9378(48)90466-9 -
Journal of the American Medical... Feb 1953
Topics: Female; Fibroma; Humans; Meigs Syndrome; Neoplasms; Ovarian Neoplasms; Ovary
PubMed: 13011088
DOI: 10.1001/jama.1953.02940090040007g -
Diseases of the Chest 1948
Topics: Female; Humans; Meigs Syndrome; Neoplasms; Ovarian Neoplasms; Ovary
PubMed: 18885811
DOI: 10.1378/chest.14.5.722 -
Digestive Surgery 2000Pseudo-Meigs' syndrome is a condition characterized by nonmalignant ascites and/or pleural effusion caused by pelvic tumors other than solid benign ovarian tumors. This... (Review)
Review
BACKGROUND
Pseudo-Meigs' syndrome is a condition characterized by nonmalignant ascites and/or pleural effusion caused by pelvic tumors other than solid benign ovarian tumors. This syndrome has only rarely occurred in association with gastrointestinal cancers.
METHOD
We treated a 53-year-old woman who developed this syndrome due to ovarian metastasis from colon cancer. Diagnostic work-up for abdominal distension disclosed a sigmoid colon cancer and bilateral ovarian masses. Ultrasonography demonstrated massive ascites and a right pleural effusion. Repeated cytologic examinations of both effusions revealed no malignant cells. Laparotomy disclosed no peritoneal dissemination. A radical sigmoidectomy and hysterectomy with bilateral salpingo-oophorectomy were performed.
RESULTS
Histologic examination confirmed ovarian metastases from the colonic primary tumor. After resection, both effusions disappeared promptly, confirming a diagnosis of pseudo-Meigs' syndrome caused by sigmoid colon cancer. The patient remains alive with disease after 52 months.
CONCLUSION
Among 6 reported occurrences with gastrointestinal tumors including our case, the primary site was the colon or rectum in 5 and the stomach in 1. Two cases were due to Krukenberg tumors. Three patients with documented outcomes were alive 108, 52, and 12 months after resection. Clinicians should note that gastrointestinal cancers, especially colorectal tumors, rarely may cause pseudo-Meigs' syndrome and resection may provide long-term palliation.
Topics: Adenocarcinoma; Colonic Neoplasms; Female; Humans; Meigs Syndrome; Middle Aged; Ovarian Neoplasms
PubMed: 11053957
DOI: 10.1159/000018893 -
Lancet (London, England) Nov 2005
Topics: Adult; Diagnosis, Differential; Female; Humans; Lupus Erythematosus, Systemic; Meigs Syndrome
PubMed: 16271650
DOI: 10.1016/S0140-6736(05)67666-0 -
Journal of Pediatric and Adolescent... Oct 2016Meigs syndrome is a rare complication associated with ovarian fibromas. Although ovarian fibromas are rare in children, they are common in women with Gorlin syndrome...
BACKGROUND
Meigs syndrome is a rare complication associated with ovarian fibromas. Although ovarian fibromas are rare in children, they are common in women with Gorlin syndrome after puberty.
CASE
A 14-year-old girl with Gorlin syndrome was admitted to our hospital for ablation of basal cell carcinoma. A chest x-ray revealed pleural effusion. Ultrasonography revealed bilateral multinodular ovarian masses. Meigs syndrome associated with ovarian fibromas was considered. A laparotomy revealed bilateral ovarian masses, which were resected. Microscopically, the masses were composed of mitotically active fibroma and areas resembling hemangiopericytoma and luteinized thecoma. The pleural effusion disappeared soon after the surgery.
SUMMARY AND CONCLUSION
Physicians should consider the possibility that pleural effusion might precede the diagnosis of ovarian fibroma in patients with Gorlin syndrome.
Topics: Adolescent; Basal Cell Nevus Syndrome; Diagnosis, Differential; Female; Fibroma; Humans; Meigs Syndrome; Ovarian Neoplasms; Pleural Effusion, Malignant
PubMed: 27079916
DOI: 10.1016/j.jpag.2016.03.010 -
Sultan Qaboos University Medical Journal May 2017The monodermal teratoma is a rare ovarian tumour; however, presenting with pseudo-Meigs' syndrome and raised cancer antigen (CA)-125 levels is even rarer. In elderly... (Review)
Review
The monodermal teratoma is a rare ovarian tumour; however, presenting with pseudo-Meigs' syndrome and raised cancer antigen (CA)-125 levels is even rarer. In elderly patients, this presentation can potentially lead to a misdiagnosis of a malignant ovarian carcinoma, resulting in unnecessary extensive surgery. We report a 55-year-old female who presented to the Lok Nayak Jai Prakash Narayan Hospital, New Delhi, India, in 2016 with progressive abdominal discomfort, fatigue and abdominal distention. Clinical and radiological features were indicative of a malignant ovarian tumour and . Serum CA-125 levels were elevated at 258 U/mL. A left-sided salpingo-oophorectomy was performed, after which the serum CA-125 levels normalised. There was no evidence of recurrence at a six-month follow-up. A frozen section procedure confirmed the diagnosis of a . This rare condition should be considered as a differential diagnosis in patients presenting with ovarian masses, and raised CA-125 levels.
Topics: Ascites; CA-125 Antigen; Diagnosis, Differential; Female; Humans; India; Meigs Syndrome; Middle Aged; Ovarian Neoplasms; Salpingo-oophorectomy; Struma Ovarii
PubMed: 28690899
DOI: 10.18295/squmj.2016.17.02.017