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Annals of Vascular Surgery May 1992The incidence of abdominal aortic aneurysm has recently increased. There is still no accurate definition of abdominal aortic aneurysm. The diameter of abdominal aortic... (Review)
Review
The incidence of abdominal aortic aneurysm has recently increased. There is still no accurate definition of abdominal aortic aneurysm. The diameter of abdominal aortic aneurysms is the only factor permitting evaluation of the risk of rupture of aneurysms whose growth remains unpredictable. Abdominal aortic aneurysm is a multi-factorial disease associated with aortic aging and atheroma. It differs from stenotic disease by the intensity of degenerative or destructive phenomena in the media. Particular hemodynamic conditions in the infrarenal abdominal aorta seem to enhance the development of aneurysm at this level. While certain constitutional anomalies of the extracellular matrix of proteins seem to enhance the development of abdominal aortic aneurysm, protease activity of as yet undetermined origin also seems to play a prominent role. Family cases of abdominal aortic aneurysms have been reported but the mechanisms responsible remain to be determined. Several genetic markers have been suggested. The most reliable marker of aortic aneurysm is arteriomegaly.
Topics: Aorta, Abdominal; Aortic Aneurysm; Collagen; Dilatation, Pathologic; Elastin; Humans
PubMed: 1610664
DOI: 10.1007/BF02000279 -
The American Journal of Emergency... Mar 2017
Topics: Abdominal Pain; Adult; Aortic Dissection; Arteritis; Celiac Artery; Constriction, Pathologic; Contrast Media; Dilatation, Pathologic; Humans; Male; Mesenteric Arteries; Mesenteric Vascular Occlusion; Tomography, X-Ray Computed
PubMed: 27742517
DOI: 10.1016/j.ajem.2016.09.036 -
Alimentary Pharmacology & Therapeutics Oct 2009While knowledge has accumulated regarding health care seeking in several functional gastrointestinal disorders (FGIDs), little is known about health care seeking in...
BACKGROUND
While knowledge has accumulated regarding health care seeking in several functional gastrointestinal disorders (FGIDs), little is known about health care seeking in those with bloating and distention.
AIM
To identify predictors of health care seeking for bloating and distention.
METHODS
The validated Talley Bowel Disease Questionnaire was mailed to a cohort selected at random from the population of Olmsted County, Minnesota; 2259 subjects (53% females; mean age 62 years) answered questions about bloating and distention. The complete medical record of each respondent was reviewed. Logistic regression was used to compare consulting for bloating and distention with consulting for other GI symptoms, and nonconsulters.
RESULTS
A total of 131 (6%) subjects in the community consulted a physician for bloating or distention. Older age [odds ratio (OR), 1.8; 95% confidence interval (CI): 1.5, 2.1], higher somatic symptom scores (OR, 2.0; CI: 1.4, 2.8), lower education level (OR, 2.7; CI: 1.2, 5.6), early satiety (OR, 2.0; CI: 1.1, 3.8) and abdominal pain (OR, 2.4; CI: 1.6, 3.7) were associated with people seeking health care for bloating or distention vs. non-consulters. Similarly, older age (OR, 1.4; CI: 1.2, 1.7), chronic constipation (OR, 2.0; CI: 1.2, 3.2) and visible distention (OR, 3.0; CI: 1.8, 4.9) had greater odds of presenting for bloating or distention compared with presenting for other GI symptoms; somatic symptoms were not a predictor (OR, 1.1; CI: 0.8, 1.5).
CONCLUSIONS
Factors that lead people to present for bloating and distention are similar to those for other GI symptoms visits; however, specific biological rather than somatic features may predict visits for bloating and distention.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Dilatation, Pathologic; Epidemiologic Methods; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Minnesota; Patient Acceptance of Health Care; Young Adult
PubMed: 19563502
DOI: 10.1111/j.1365-2036.2009.04080.x -
NeoReviews Apr 2021
Topics: Abdomen; Dilatation, Pathologic; Humans; Infant, Newborn
PubMed: 33795401
DOI: 10.1542/neo.22-4-e258 -
Revista Espanola de Enfermedades... Dec 2000
Topics: Abdomen; Dilatation, Pathologic; Gastrointestinal Diseases; Humans
PubMed: 11468793
DOI: No ID Found -
Alimentary Pharmacology & Therapeutics May 2011Abdominal bloating and distension are common symptoms in patients with functional gastrointestinal disorders (FGIDs), however, relatively little is known about their... (Review)
Review
BACKGROUND
Abdominal bloating and distension are common symptoms in patients with functional gastrointestinal disorders (FGIDs), however, relatively little is known about their treatment.
AIM
To review the treatment trials for abdominal bloating and distension.
METHODS
A literature review in Medline for English-language publications through February 2010 of randomised, controlled treatment trials in adults. Study quality was assessed according to Jadad's score.
RESULTS
Of the 89 studies reviewed, 18% evaluated patients with functional dyspepsia, 61% with irritable bowel syndrome (IBS), 10% with chronic constipation and 10% with other FGIDs. No studies were conducted in patients diagnosed with functional abdominal bloating. The majority of trials investigated the efficacy of prokinetics or probiotics, although studies are heterogeneous with respect to diagnostic criteria and outcome measures. In general, bloating and/or distension were evaluated as secondary endpoints or as individual symptoms as part of a composite score rather than as primary endpoints. A greater proportion of IBS patients with constipation reported improvement in bloating with tegaserod vs. placebo (51% vs. 40%, P<0.0001) and lubiprostone (P<0.001). A greater proportion of nonconstipating IBS patients reported adequate relief of bloating with rifaximin vs. placebo (40% vs. 30%, P<0.001). Bloating was significantly reduced with the probiotics, Bifidobacterium infantis 35624 (1×10(8) dose vs. placebo: -0.71 vs. -0.44, P<0.05) and B. animalis (live vs. heat-killed: -0.56±1.01 vs. -0.31±0.87, P=0.03).
CONCLUSIONS
Prokinetics, lubiprostone, antibiotics and probiotics demonstrate efficacy for the treatment of bloating and/or distension in certain FGIDs, but other agents have either not been studied adequately or have shown conflicting results.
Topics: Abdomen; Dilatation, Pathologic; Flatulence; Gases; Gastric Dilatation; Gastrointestinal Agents; Gastrointestinal Transit; Humans; Probiotics; Randomized Controlled Trials as Topic
PubMed: 21488913
DOI: 10.1111/j.1365-2036.2011.04637.x -
Journal of Paediatrics and Child Health Nov 2017
Topics: Diagnosis, Differential; Dilatation, Pathologic; Female; Humans; Infant, Newborn; Prune Belly Syndrome; Urinary Tract
PubMed: 29148195
DOI: 10.1111/jpc.2_13791 -
Surgical Endoscopy Jan 2003Choledochocele, now classified as choledochal cyst type III, is a rare anomaly of the terminal biliary tree causing abdominal pain, pancreatitis, and obstructive...
Choledochocele, now classified as choledochal cyst type III, is a rare anomaly of the terminal biliary tree causing abdominal pain, pancreatitis, and obstructive cholestasis. Traditionally, the therapy for this malformation has been surgery. Recently, endoscopic therapy has been used alternatively for the treatment of choledochocele mainly in adults. We report two patients with recurrent episodes of acute pancreatitis found to be caused by a large choledochocele; both patients were treated by needle-knife sphincterotomy without complications. They remained asymptomatic at 1 and 2 years' follow-up, respectively. Despite the fact that the risk of bleeding seems to be higher using needle-knife sphincterotomy, when the Choledochocele is large, our experience suggests that needle-knife sphincterotomy can be performed accurately and safely. Further studies are necessary to confirm the safety and effectiveness of needle-knife sphincterotomy in large choledochocles.
Topics: Acute Disease; Aged; Choledochal Cyst; Dilatation, Pathologic; Female; Follow-Up Studies; Humans; Middle Aged; Pancreatitis; Recurrence; Sphincterotomy, Endoscopic; Treatment Outcome
PubMed: 12399865
DOI: 10.1007/s00464-002-4240-3 -
Vascular 2009Atherosclerotic plaques are a feature of abdominal aortic aneurysms (AAAs). Atherosclerosis and AAA appear to share similar risk factors. These observations have led to... (Review)
Review
Atherosclerotic plaques are a feature of abdominal aortic aneurysms (AAAs). Atherosclerosis and AAA appear to share similar risk factors. These observations have led to the conclusion that AAAs are a consequence of advanced atherosclerosis.This review explores current theories regarding the pathogenesis of AAA and their implications for treatment.A systematic literature search was conducted using the search terms abdominal aortic aneurysm, atherosclerosis, pathogenesis, and systemic disease. Articles were categorized according to the association of AAAs with atherosclerosis, arteriomegaly, peripheral aneurysm, systemic expression, genetics, autoimmunity, oxidative stress, and systemic disease. Twenty-nine articles reporting changes in the systemic vasculature associated with AAA and 12 articles examining the shared risk factor hypothesis were identified.There is insufficient evidence to confirm that AAAs are the result of advanced atherosclerosis. The bulk of evidence points to AAA disease being a systemic disease of the vasculature, with a predetermined genetic susceptibility leading to a phenotype governed by environmental factors.
Topics: Aortic Aneurysm, Abdominal; Atherosclerosis; Autoimmunity; Dilatation, Pathologic; Female; Genetic Predisposition to Disease; Humans; Male; Oxidative Stress; Risk Factors
PubMed: 19769804
DOI: 10.2310/6670.2009.00046 -
BMJ Case Reports May 2017
Topics: Abdomen; Dilatation, Pathologic; Female; Humans; Middle Aged; Multimodal Imaging; Necrosis; Neurilemmoma; Peritoneum; Retroperitoneal Neoplasms; Tomography, X-Ray Computed
PubMed: 28500128
DOI: 10.1136/bcr-2017-220221