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The Journal of Family Practice Oct 2023The diagnosis of this patient's inflammatory condition required us to dig deeper.
The diagnosis of this patient's inflammatory condition required us to dig deeper.
Topics: Humans; Acne Vulgaris
PubMed: 37862622
DOI: 10.12788/jfp.0658 -
Der Hautarzt; Zeitschrift Fur... May 2009Acne is the most common disease in teens, with a prevalence of about 80-90%. The severity of acne varies greatly among individuals, and genetic background plays an... (Review)
Review
Acne is the most common disease in teens, with a prevalence of about 80-90%. The severity of acne varies greatly among individuals, and genetic background plays an important role. Pathogenetic factors include androgen-induced seborrhea, follicular hyperkeratosis, microbial population, and immunological and inflammatory processes. These factors influence each other, leading to the acne phenotype. Classical acne forms must be differentiated from special acne entities. Among those, acne induced by self-administered anabolic steroids ("bodybuilding acne") has especially become a widespread problem. Psychological effects induced by the disfiguring appearance of severe acne manifestations in pubertal adolescents should not be underestimated. Acne juvenilis may be well controlled by a variety of pathogenesis-oriented antiacne treatment strategies. Because the treatment is always longstanding, and success is achieved only after a prolonged period of time, a very good patient-doctor relationship is required.
Topics: Acne Vulgaris; Child; Dermatologic Agents; Humans
PubMed: 19430752
DOI: 10.1007/s00105-008-1689-6 -
Acta Dermatovenerologica Croatica : ADC Jul 2017Acne is one of the most common skin disorders. It is a multifactorial and complex disease, originating in the pilosebaceous follicle where a hereditary background,... (Review)
Review
Acne is one of the most common skin disorders. It is a multifactorial and complex disease, originating in the pilosebaceous follicle where a hereditary background, androgens, skin lipids, disorders of keratinization, inflammatory signaling, and regulatory neuropeptides seem to be mainly involved. Even though emotional stress has long been suspected to trigger or exacerbate acne, its influence on acne severity has been mostly underestimated until recently when studies have brought new data about the different mechanisms and possible factors involved in this interaction. A point to note is that there have been relatively few studies examining stress as a possible cause of acne or acne exacerbation; more studies have focused on stress and mental health problems occurring as a result of acne. In this review, we have tried to identify the underlying mechanisms that link stress to acne according to the latest scientific findings, and we summarize this perplexing connection. The basis for the association between emotional stress and the onset or exacerbation of acne is in several cutaneous neurogenic factors which interact with a pathogenic cascade in acne. This bidirectional intimate relationship of the skin and the mind emphasizes the importance of a holistic and interdisciplinary approach to caring for patients with acne that involves not only dermatologists but also psychologists and psychiatrists.
Topics: Acne Vulgaris; Humans; Stress, Psychological
PubMed: 28871928
DOI: No ID Found -
Adolescent Medicine (Philadelphia, Pa.) Jun 2001Acne vulgaris, more commonly termed acne, is the most common skin disease treated by physicians. It affects an estimated 17 million people in the United States,... (Review)
Review
Acne vulgaris, more commonly termed acne, is the most common skin disease treated by physicians. It affects an estimated 17 million people in the United States, including 85% or more of adolescents and young adults. Acne is a chronic condition that may last for years and cause emotional distress and permanent scarring. Although there is no cure, medications can control the disease and limit or prevent scar formation.
Topics: Acne Vulgaris; Adolescent; Adult; Female; Humans; Male; Patient Education as Topic
PubMed: 11404206
DOI: No ID Found -
Journal Der Deutschen Dermatologischen... Apr 2007
Review
Topics: Acne Vulgaris; Humans; Models, Biological; Skin
PubMed: 17376098
DOI: 10.1111/j.1610-0387.2007.06274.x -
Seminars in Cutaneous Medicine and... Sep 2011Acne is no longer simply a diagnosis based on the appearance of characteristic lesions on the skin of adolescents. The presentation of acne differs across age groups,... (Review)
Review
Acne is no longer simply a diagnosis based on the appearance of characteristic lesions on the skin of adolescents. The presentation of acne differs across age groups, and the population of younger pediatric patients with acne continues to grow. This article addresses the changing epidemiology and demographics of acne, with specific emphasis on the 7- to 11-year-old acne patient population; the differences and similarities between pediatric acne and adolescent acne; age-based acne epidemiology; and current perspectives on acne etiology.
Topics: Acne Vulgaris; Adolescent; Age of Onset; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Puberty
PubMed: 21943564
DOI: 10.1016/j.sder.2011.07.003 -
Biomedicine & Pharmacotherapy =... Aug 2023Acne vulgaris is a highly prevalent skin condition caused by androgen-induced elevated sebum secretion, abnormal keratinization, bacterial colonization, and... (Review)
Review
Acne vulgaris is a highly prevalent skin condition caused by androgen-induced elevated sebum secretion, abnormal keratinization, bacterial colonization, and inflammation. Current research indicates a link between acne vulgaris and the metabolic syndrome, a group of disorders that includes obesity, insulin resistance, hypertension, and dyslipidemia. This link is thought to be modulated by excessive concentrations of oxidative stress markers and chronic inflammation, which are included in the pathophysiological mechanisms shared by both conditions. Excessive generation of reactive oxygen species damages cellular components and initiates an inflammatory response, hence promoting the development of both disorders. The current narrative review focuses on the molecular implications of inflammatory, hormonal, and environmental factors in the acne-metabolic syndrome correlation. Furthermore, it outlines the current state of knowledge related to the phyto-therapeutic approach to these conditions as an adjuvant strategy to allopathic treatment, but future multicenter and larger-scale research studies are needed establish new algorithms to be included in the future management of patients with these conditions.
Topics: Humans; Metabolic Syndrome; Acne Vulgaris; Oxidative Stress; Inflammation; Dietary Supplements; Phytochemicals; Multicenter Studies as Topic
PubMed: 37315434
DOI: 10.1016/j.biopha.2023.115003 -
Acta Dermatovenerologica Croatica : ADC 2012Acne is a common skin disorder characterized by follicular hyperkeratinization and obstruction of the pilosebaceous follicles, androgen stimulated sebum production,... (Review)
Review
Acne is a common skin disorder characterized by follicular hyperkeratinization and obstruction of the pilosebaceous follicles, androgen stimulated sebum production, colonization of the follicles by Propionibacterium acne, and inflammation. A large number of epidemiological studies have shown a low incidence of acne in non-Western societies, suggesting that diet might be an important factor in acne pathogenesis, particularly in mediating inflammation, oxidative stress and androgen stimulation in the acne process. Consequently, it has been hypothesized that diet might have a preventive or therapeutic effect in this skin disorder. Since the majority of recent data have not been consistent, the aim of this article is to present current knowledge and scientific assumptions on the relationship between diet and acne.
Topics: Acne Vulgaris; Diet; Humans
PubMed: 23069302
DOI: No ID Found -
Plastic Surgical Nursing : Official... 2005
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The Medical Clinics of North America Sep 1998The diagnosis of acne and rosacea are reviewed in this article, and specific therapeutic strategies are discussed for these extremely common diseases. (Review)
Review
The diagnosis of acne and rosacea are reviewed in this article, and specific therapeutic strategies are discussed for these extremely common diseases.
Topics: Acne Vulgaris; Diagnosis, Differential; Humans; Rosacea
PubMed: 9769797
DOI: 10.1016/s0025-7125(05)70407-7