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Cleveland Clinic Quarterly Jan 1954
Topics: Cochlear Nerve; Cranial Nerve Neoplasms; Humans; Neoplasms; Vestibulocochlear Nerve Diseases
PubMed: 13116421
DOI: 10.3949/ccjm.21.1.40 -
Audiology : Official Organ of the... 1977The responses of the auditory nerve and brain stem auditory nuclei have been recorded with ear lobe and scalp electrodes in response to unfiltered click stimuli which...
The responses of the auditory nerve and brain stem auditory nuclei have been recorded with ear lobe and scalp electrodes in response to unfiltered click stimuli which excite mainly high-frequency nerve fibers. In order to overcome this limitation, normal subjects and patients with hearing loss were stimulated with third-octave filtered clicks with center frequencies of 250, 500 and 1 000 Hz. Analysis of the responses suggests that these lower-frequency stimuli excite lower-frequency cochlear nerve fibers. It is concluded that low-frequency filtered clicks can be used to complement unfiltered clicks in order to obtain a more complete objective audiogram.
Topics: Acoustic Stimulation; Action Potentials; Audiometry; Auditory Pathways; Brain Stem; Cochlear Nerve; Hearing Disorders; Humans
PubMed: 901294
DOI: 10.3109/00206097709071853 -
The Laryngoscope Feb 1965
Review
Topics: Anatomy; Cochlear Nerve; Ear, Inner; Electrophysiology; History; History, 19th Century; History, 20th Century; Humans; Neurons; Neurophysiology; Vestibular Nerve; Vestibulocochlear Nerve
PubMed: 14270671
DOI: 10.1288/00005537-196502000-00002 -
The Laryngoscope Nov 1963
Topics: Action Potentials; Audiometry; Cats; Cochlear Nerve; Electrophysiology; Evoked Potentials; Meniere Disease; Research; Vestibulocochlear Nerve
PubMed: 14071937
DOI: 10.1288/00005537-196311000-00002 -
Proceedings of the National Academy of... Aug 2006Binaural auditory neurons exhibit "best delays" (BDs): They are maximally activated at certain acoustic delays between sounds at the two ears and thereby signal spatial...
Binaural auditory neurons exhibit "best delays" (BDs): They are maximally activated at certain acoustic delays between sounds at the two ears and thereby signal spatial sound location. BDs arise from delays internal to the auditory system, but their source is controversial. According to the classic Jeffress model, they reflect pure time delays generated by differences in axonal length between the inputs from the two ears to binaural neurons. However, a relationship has been reported between BDs and the frequency to which binaural neurons are most sensitive (the characteristic frequency), and this relationship is not predicted by the Jeffress model. An alternative hypothesis proposes that binaural neurons derive their input from slightly different places along the two cochleas, which induces BDs by virtue of the slowness of the cochlear traveling wave. To test this hypothesis, we performed a coincidence analysis on spiketrains of pairs of auditory nerve fibers originating from different cochlear locations. In effect, this analysis mimics the processing of phase-locked inputs from each ear by binaural neurons. We find that auditory nerve fibers that innervate different cochlear sites show a maximum number of coincidences when they are delayed relative to each other, and that the optimum delays decrease with characteristic frequency as in binaural neurons. These findings suggest that cochlear disparities make an important contribution to the internal delays observed in binaural neurons.
Topics: Animals; Auditory Pathways; Cochlear Nerve; Inferior Colliculi
PubMed: 16908859
DOI: 10.1073/pnas.0601396103 -
Hearing Research Dec 2004The use of penetrating, silicon-substrate (i.e., "thin-film") probes within a cross-section of a sensory nerve offers the possibility of assessing the pattern and extent...
The use of penetrating, silicon-substrate (i.e., "thin-film") probes within a cross-section of a sensory nerve offers the possibility of assessing the pattern and extent of fiber excitation within the nerve. We used acute cat preparations to assess the feasibility of this technique for recordings within the auditory nerve trunk. Four probe configurations fabricated by the University of Michigan Center for Neural Communication Technology were evaluated using acoustic and electric stimuli. Our main concerns were the nature of the recorded potentials and the degree of spatial selectivity provided by these probes. We also made some basic assessments of electrode-tissue compatibility. The recorded potentials were characterized as field potentials with varying degrees of spatial selectivity. In some cases, responses to pure tones demonstrated good spatial selectivity, with unique responses recorded by different electrode sites. When electrode sites were positioned at different longitudinal positions along the nerve trunk, responses with latencies characteristic of each site were recorded. These results indicate that thin-film electrodes are capable of providing spatially specific response information from sensory nerves. However, in the case of feline auditory nerves, place-specific responses were inconsistently observed, making it difficult to use this technique to obtain detailed cochleotopic maps of neural excitation. More productive results may be possible from other peripheral nerves with less complex spatial arrangements of fibers.
Topics: Acoustic Stimulation; Animals; Cats; Cochlear Nerve; Electric Stimulation; Evoked Potentials, Auditory; Microelectrodes; Neurophysiology; Silicones
PubMed: 15567602
DOI: 10.1016/j.heares.2004.07.009 -
Archives of Otolaryngology (Chicago,... Dec 1964
Topics: Cochlear Nerve; Ear, Inner; Neoplasms; Neurilemmoma; Neuroma, Acoustic; Petrous Bone; Radiography; Vestibulocochlear Nerve; X-Rays
PubMed: 14205470
DOI: 10.1001/archotol.1964.00750040711011 -
Acta Otorrinolaringologica Espanola Feb 2002The standard translabyrinthine approach for acoustic neuromas removal was introduced by W. House in 1964. After several years of experience the original...
The standard translabyrinthine approach for acoustic neuromas removal was introduced by W. House in 1964. After several years of experience the original translabyrinthine approach has been progressively modified into the current "enlarged" approach by extending the area of bone removal. This increased surgical field has made the translabyrinthine approach suitable for the removal of tumours of all sizes. We present our serie of 71 large (52) and giant (19) neuromas of the VIIIth nerve removed through a translabyrinthine approach between 1993 and 1998 at the ENT Department of Legnano.
Topics: Adolescent; Adult; Aged; Cochlear Nerve; Ear, Inner; Facial Nerve Diseases; Female; Humans; Male; Middle Aged; Neuroma, Acoustic; Otologic Surgical Procedures; Postoperative Complications; Severity of Illness Index
PubMed: 11998533
DOI: 10.1016/s0001-6519(02)78287-3 -
Pflugers Archiv Fur Die Gesamte... Jun 1964
Topics: Arousal; Cats; Cochlear Nerve; Ear, Middle; Electroencephalography; Electromyography; Research; Sleep; Wakefulness
PubMed: 14251608
DOI: 10.1007/BF00412618 -
Brain : a Journal of Neurology 1951
Topics: Cochlear Nerve; Humans; Neoplasms; Neurofibroma
PubMed: 14858745
DOI: 10.1093/brain/74.2.144