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International Journal of Audiology Apr 2024
Topics: Humans; Hearing Loss, Noise-Induced
PubMed: 37029688
DOI: 10.1080/14992027.2023.2197147 -
California Medicine Nov 1967Analysis of certain measurements of noise levels and frequency distributions in two rock-and-roll music establishments indicated that this program material can produce...
Analysis of certain measurements of noise levels and frequency distributions in two rock-and-roll music establishments indicated that this program material can produce temporary auditory threshold shifts and is of an order that has been recognized as entailing risk of permanent ear damage.
Topics: Amplifiers, Electronic; Hearing Loss, Noise-Induced; Humans; Music
PubMed: 6083240
DOI: No ID Found -
Laryngo- Rhino- Otologie Jan 2023
Topics: Humans; Hearing Loss, Noise-Induced; Tinnitus; Workers' Compensation; Occupational Diseases; Expert Testimony
PubMed: 36580930
DOI: 10.1055/a-1973-0015 -
Audiology : Official Organ of the... 198356 Subjects complaining of tinnitus underwent an audiometric test and a test for identifying the analogous pitch of their tinnitus. All of the subjects reported that...
56 Subjects complaining of tinnitus underwent an audiometric test and a test for identifying the analogous pitch of their tinnitus. All of the subjects reported that they had been exposed to noise in the past. The subjects were divided into two groups on the basis of their audiometric test results. Group P was composed of subjects who showed a sensorineural hearing loss typical of acoustic trauma. Group N was composed of subjects whose hearing was within normal limits. The pitch of the tinnitus in group P was concentrated in the high-frequency range, whereas in group N tinnitus pitch values were distributed over the low and mid-audiometric frequency spectrum. It was deduced that different processes are involved in the generation of tinnitus in the two groups.
Topics: Adult; Audiometry, Pure-Tone; Audiometry, Speech; Hearing Loss, High-Frequency; Hearing Loss, Noise-Induced; Humans; Male; Pitch Perception; Tinnitus
PubMed: 6615340
DOI: 10.3109/00206098309072795 -
The Laryngoscope Apr 1960
Topics: Cochlea; Ear, Inner; Hearing Loss, Noise-Induced; Humans; Otologic Surgical Procedures
PubMed: 14443732
DOI: 10.1288/00005537-196004000-00011 -
Acta Oto-laryngologica Aug 2011The findings from this study extend the use of the local application of D-methionine (D-met) to protect against acoustic trauma and demonstrate that D-met slowly... (Comparative Study)
Comparative Study
CONCLUSION
The findings from this study extend the use of the local application of D-methionine (D-met) to protect against acoustic trauma and demonstrate that D-met slowly diffuses from the perilymph.
OBJECTIVES
The objectives of the study were to determine the effect of D-met on auditory function and morphology after acoustic trauma and to measure the concentration of D-met in perilymph.
METHODS
Auditory thresholds were determine before, immediately after, and 24 h after acoustic trauma. Cochleae were analyzed using immunocytochemistry for c-Fos, TUJI, and cytochrome c. The concentration of D-met was determined from perilymph.
RESULTS
Protection against acoustic trauma (immediately and 24 h post trauma) on auditory brainstem thresholds was found at a time when the concentration of D-met in perilymph showed a fivefold increase above basal levels. The local application of D-met to the guinea pig cochlea results in elevated D-met concentrations that are maintained in the perilymph for at least 24 h.
Topics: Administration, Topical; Animals; Auditory Threshold; Disease Models, Animal; Ear, Inner; Female; Guinea Pigs; Hearing Loss, Noise-Induced; Methionine; Treatment Outcome
PubMed: 21480759
DOI: 10.3109/00016489.2011.564652 -
Duodecim; Laaketieteellinen... 2010Acute acoustic trauma (AAT) may result from a single, intense impulse noise, or from brief exposure to strong noise. Ringing in the ear in consequence of noise exposure...
Acute acoustic trauma (AAT) may result from a single, intense impulse noise, or from brief exposure to strong noise. Ringing in the ear in consequence of noise exposure is the first alarm indicating that the tolerance of the inner ear has been exceeded. The ringing will be accompanied by hearing impairment, stuffiness and blocking. Other symptoms may also appear. The symptoms disappear in most people after the cessation of noise, but in some the symptoms remain persistent or permanent. Treatment options are limited.
Topics: Acute Disease; Hearing Loss, Noise-Induced; Humans; Tinnitus
PubMed: 21125751
DOI: No ID Found -
Acta Oto-laryngologica. Supplementum 1978
Topics: Animals; Auditory Threshold; Behavior, Animal; Cats; Cochlea; Hair Cells, Auditory; Hearing Loss, Noise-Induced; Nerve Fibers; Neurons; Vestibulocochlear Nerve
PubMed: 281107
DOI: No ID Found -
Acta Otorrinolaringologica Espanola Nov 2007To confirm the existence of acoustic trauma in classical musicians.
OBJECTIVE
To confirm the existence of acoustic trauma in classical musicians.
MATERIAL AND METHOD
Sixty-five volunteers from the Castilla and León Symphony Orchestra were studied. The hearing thresholds of each musician were age-corrected using the ELI and ISO 7029:2000 scales. Furthermore the sound levels of the instruments in this symphony orchestra were studied.
RESULTS
We observed that the sound level of the symphony orchestra instruments is higher than the level permitted by law, ie it constitutes a risk for hearing loss. We also found that 4 kHz hearing loss in the 5th percentile among musicians was double the rate that would be expected for age, and that violinists and viola players showed poorer hearing in the left ear.
CONCLUSIONS
Classical music causes acoustic trauma in musicians and should be recognized as a professional illness. Musicians are obliged to protect their hearing and to undergo regular check-ups.
Topics: Adult; Aged; Audiometry, Pure-Tone; Female; Hearing Loss, Noise-Induced; Humans; Male; Middle Aged; Music; Occupational Diseases; Severity of Illness Index
PubMed: 17999904
DOI: No ID Found -
European Archives of... Jul 2019The aim of this study was to investigate the potential protective and therapeutic effects of milrinone, a specific phosphodiesterase (PDE) III inhibitor, on acoustic...
OBJECTIVE
The aim of this study was to investigate the potential protective and therapeutic effects of milrinone, a specific phosphodiesterase (PDE) III inhibitor, on acoustic trauma-induced cochlear injury and apoptosis.
METHODS
A total number of 30 healthy Wistar albino rats were evenly divided into five groups as follows: group 1 was assigned as control group; group 2 and 3 were assigned as low-dosage groups (0.25 mg/kg) in which milrinone was administered 1 h before acoustic trauma (AT) and 2 h after AT, respectively; group 4 and 5 were assigned as high-dosage groups (0.50 mg/kg) in which the drug was administered 1 h before AT and 2 h after AT, respectively. Except control group, all treatment groups received a single dosage of milrinone for 5 days. Distortion product otoacoustic emissions (DPOAE) measurements were recorded before AT as well as at second and fifth post-traumatic days. At the end of fifth day, all rats were sacrificed and the cochlea of the rats was removed for histopathological evaluation. In addition, the groups were compared in terms of apoptotic index via caspase-3 staining.
RESULTS
In terms of signal-to-noise ratio (SNR), there was no statistically significant difference among the groups following AT (p > 0.05). After 5 days of milrinone treatment, the best SNR values were found in group 5, though all groups did not statistically differ (p > 0.05). In histopathological evaluation, vacuolization, inflammation, and edema scores in all treatment groups were statistically lower than those of the control group (p < 0.05). In group 2 and 4 where the drug was administered before AT, the inflammation and apoptosis index was lower than those of group 3 and 5 where the drug was administered after AT (p < 0.0001).
CONCLUSION
We reveal that milrinone has a protective effect on cochlear damage in the experimental acoustic model of rats. This protective effect was more apparent following the pre-traumatic milrinone administration, and is associated with its effect on decreasing inflammation and apoptosis. Based on DPOAE measurements following AT, especially in the group 5 (high-dosage group), milrinone may also have a therapeutic effect.
Topics: Animals; Apoptosis; Audiometry; Cochlea; Hearing Loss, Noise-Induced; Male; Milrinone; Phosphodiesterase 3 Inhibitors; Rats; Rats, Wistar; Treatment Outcome
PubMed: 30955065
DOI: 10.1007/s00405-019-05417-5