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Skinmed 2005Dercum's disease (adiposis dolorosa, lipomatosis dolorosa morbus Dercum), is a rare disorder resulting in painful fatty deposits around the upper legs, trunk, and upper... (Review)
Review
Dercum's disease (adiposis dolorosa, lipomatosis dolorosa morbus Dercum), is a rare disorder resulting in painful fatty deposits around the upper legs, trunk, and upper arms. The portrait painted of Dercum's disease is very complicated, with many other disorders seen associated with the disease. There are no clear pathological mechanisms known, although it is suspected that there is either a metabolic or autoimmune component involved. Here, the authors review the literature to date, including some information from their own studies. In particular, the authors will look at the different strands of evidence pointing to the pathological mechanism of the disorder.
Topics: Adiposis Dolorosa; Humans
PubMed: 15891252
DOI: 10.1111/j.1540-9740.2005.03675.x -
Proceedings of the Royal Society of... 1923
PubMed: 19982794
DOI: No ID Found -
Proceedings of the Royal Society of... 1910
PubMed: 19974159
DOI: No ID Found -
Archives of Dermatology Feb 1991Long-term treatment with high doses of corticosteroids leads to the development of truncal obesity and focal fatty deposition. These deposits characteristically are...
Long-term treatment with high doses of corticosteroids leads to the development of truncal obesity and focal fatty deposition. These deposits characteristically are located on the face, the nuchal and truncal areas, and episternally, as well as in the mediastinum and epicardium. We studied a patient with juxta-articular adiposis dolorosa who had L-tryptophan-associated eosinophilia-myalgia syndrome and was treated with high doses of prednisone. This is the first reported case of adiposis dolorosa occurring as a complication of corticosteroid treatment. Alterations of fat metabolism induced by corticosteroid excess may have played a role in the development of this unusual painful syndrome.
Topics: Adiposis Dolorosa; Aged; Female; Humans; Joint Diseases; Knee Joint; Prednisone
PubMed: 1990989
DOI: No ID Found -
Wiener Medizinische Wochenschrift (1946) Apr 1959
Topics: Adiposis Dolorosa
PubMed: 13648424
DOI: No ID Found -
Dermatologic Surgery : Official... Dec 2019
Topics: Adiposis Dolorosa; Deoxycholic Acid; Humans; Injections, Intralesional; Male; Middle Aged; Off-Label Use; Treatment Outcome
PubMed: 30789509
DOI: 10.1097/DSS.0000000000001800 -
The Journal of Laryngology and Otology Feb 1999Dercum's disease (adiposis dolorosa) is a rare condition characterized by progressively painful fatty deposits, usually, in menopausal women with obesity, asthenia and...
Dercum's disease (adiposis dolorosa) is a rare condition characterized by progressively painful fatty deposits, usually, in menopausal women with obesity, asthenia and mental phenomena. We report a case of a 48-year-old woman with recurrent neck swelling and pain in the neck and parotid region, and a review of management of this uncommon problem.
Topics: Adipose Tissue; Adiposis Dolorosa; Anti-Arrhythmia Agents; Female; Humans; Mexiletine; Middle Aged; Pain; Parotid Gland
PubMed: 10396574
DOI: 10.1017/s0022215100143506 -
Journal Der Deutschen Dermatologischen... Apr 2024
Topics: Humans; Lipoma; Adiposis Dolorosa
PubMed: 38506609
DOI: 10.1111/ddg.15362 -
The Journal of Headache and Pain Dec 2010A 46-year-old female, known case of adiposis dolorosa since adolescence, noticed painful thickening of scalp in bilateral parieto-occipital areas and vertex 1 year back....
A 46-year-old female, known case of adiposis dolorosa since adolescence, noticed painful thickening of scalp in bilateral parieto-occipital areas and vertex 1 year back. Six weeks prior to the presentation to our service, she developed severe occipital headache refractory to drug treatment. She improved after bilateral greater occipital nerve blocks. She was subjected to bilateral greater occipital chemical neurolysis which has given her complete pain relief.
Topics: Adiposis Dolorosa; Diagnosis, Differential; Female; Headache Disorders; Humans; Middle Aged; Neuralgia; Scalp; Spinal Nerves
PubMed: 20811764
DOI: 10.1007/s10194-010-0253-9 -
Wiadomosci Lekarskie (Warsaw, Poland :... 2009
Topics: Adiposis Dolorosa; Arteriosclerosis; Female; Humans; Hypercholesterolemia; Middle Aged; Myocardial Infarction
PubMed: 19817260
DOI: No ID Found