-
Naika. Internal Medicine Feb 1970
Topics: Aged; Angiography; Autopsy; Brain; Female; Humans; Intracranial Aneurysm; Mutism
PubMed: 5438424
DOI: No ID Found -
Functional Neurology 1988
Review
Topics: Akinetic Mutism; Cognition Disorders; Consciousness Disorders; Humans
PubMed: 3292349
DOI: No ID Found -
Acta Neurologica Belgica Jun 2014
Topics: Akinetic Mutism; Cognition Disorders; Diffusion Magnetic Resonance Imaging; Functional Laterality; Humans; Male; Middle Aged; Psychomotor Performance; Stroke; Thalamus
PubMed: 23775322
DOI: 10.1007/s13760-013-0213-7 -
Revue Neurologique Mar 1996A 65 years old woman with chronic high blood pressure and diabetes mellitus presented with a mutism akinetic of sudden onset and a right total hemiplegia with a Babinski... (Review)
Review
A 65 years old woman with chronic high blood pressure and diabetes mellitus presented with a mutism akinetic of sudden onset and a right total hemiplegia with a Babinski sign secondary to a left anterior cerebral artery infarction. She had had six months earlier a transient gait disturbance. At that time, the CT scan showed lacunar infarcts of the head of both caudate nuclei. Neuropathological examination revealed that the left infarction of the anterior cerebral artery involved the superior frontal gyrus, the supplementary motor area, the cingulate gyrus and the corpus callosum. There were also multiple lacunes of the head of both caudate nuclei, anterior limb of the internal capsules, white matter, basal ganglia and thalami. The mutism akinetic was thought to be the result of a bilateral disruption of a functional loop including on each side, the supplementary motor area, the cingulate gyrus, the subcallosal tract and the head of the caudate nucleus. On the right side, the lesion of the caudate nucleus could have interrupted this loop normally involved in the induction of voluntary movements and in the communication with the external surroundings.
Topics: Aged; Akinetic Mutism; Brain; Cerebral Arteries; Cerebral Infarction; Female; Hemiplegia; Humans
PubMed: 8761628
DOI: No ID Found -
Case Reports in Neurological Medicine 2016We report on two cases of transient akinetic mutism after massive subarachnoid haemorrhage due to the rupture of an intracranial aneurysm of the anterior cerebral artery...
Reversible Akinetic Mutism after Aneurysmal Subarachnoid Haemorrhage in the Territory of the Anterior Cerebral Artery without Permanent Ischaemic Damage to Anterior Cingulate Gyri.
We report on two cases of transient akinetic mutism after massive subarachnoid haemorrhage due to the rupture of an intracranial aneurysm of the anterior cerebral artery (ACA). In the two cases, vasospasm could not be demonstrated by imaging studies throughout the clinical course. Both patients shared common radiological features: a hydrocephalus due to haemorrhagic contamination of the ventricular system and a mass effect of a subpial hematoma on the borders of the corpus callosum. Patients were also investigated using auditory event-related evoked potentials at acute stage. In contrast to previous observations of akinetic mutism, P300 wave could not be recorded. Both patients had good recovery and we hypothesized that this unexpectedly favourable outcome was due to the absence of permanent structural damage to the ACA territory, with only transient dysfunction due to a reversible mass effect on cingulate gyri.
PubMed: 27418987
DOI: 10.1155/2016/5193825 -
Revue Neurologique Mar 2002
Review
Topics: Akinetic Mutism; Anterior Cerebral Artery; Anticholesteremic Agents; Anticoagulants; Cerebellum; Cerebral Cortex; Cerebral Infarction; Cerebrovascular Circulation; Consciousness Disorders; Cote d'Ivoire; Diabetes Mellitus, Type 2; Female; France; Headache; Humans; Hypercholesterolemia; Hypertension; Insulin; Magnetic Resonance Imaging; Middle Aged; Paraplegia; Parenteral Nutrition; Vertigo
PubMed: 11976602
DOI: No ID Found -
Psychiatria Et Neurologia Dec 1959
Topics: Akinetic Mutism; Brain Neoplasms; Craniopharyngioma; Humans; Mental Disorders; Pituitary Neoplasms
PubMed: 14414680
DOI: 10.1159/000132824 -
European Journal of Neurology May 2002In a 59-year-old female patient, a World Health Organization (WHO) grade II astrocytoma had been diagnosed 16 years ago, which finally progressed into WHO grade III....
In a 59-year-old female patient, a World Health Organization (WHO) grade II astrocytoma had been diagnosed 16 years ago, which finally progressed into WHO grade III. Several right frontal neurosurgical resections, local radiation and a local radioimplant had been applied. Despite this long record, she was reported alert with a Karnofsky index of 90% until admission. Within a few weeks she rapidly developed akinetic mutism. Upon admission, computed tomography (CT) scan showed a large cystic right frontal defect and a suggested small tumor recurrence. White matter of the frontal lobe appeared to be translucent and compatible with previous radiation. The severe mental changes were initially attributed to a delayed radiation encephalopathy. Neuropathologically, the white matter of the frontal lobe showed mild elevated cell density consistent with gliosis; however, a tumor recurrence invading the tip of the corpus callosum and invading the entire length both fornices appeared. From the neuropathological findings of massive local tumor recurrence in both fornices, together with the acute clinical onset, it seems unlikely that the sequel of radiotherapy caused akinetic mutism, but the symmetric and severe involvement of the limbic system. We conclude that the rapid progression from a state of alertness to a full clinical picture of akinetic mutism was because of infiltration of both fornices.
Topics: Akinetic Mutism; Astrocytoma; Brain Neoplasms; Fatal Outcome; Female; Fornix, Brain; Humans; Middle Aged
PubMed: 11985642
DOI: 10.1046/j.1468-1331.2002.00386.x -
Journal of the Neurological Sciences Jul 1996A 42-year-old man presented with akinetic mutism, caused by bilateral thalamic infarction, resulting in a temporary amnesic syndrome and, finally, selective downgaze...
A 42-year-old man presented with akinetic mutism, caused by bilateral thalamic infarction, resulting in a temporary amnesic syndrome and, finally, selective downgaze palsy. Electroencephalographic recording in the initial phase showed generalized spike- and-wave discharges, similar to those found in animal studies after lesion or stimulation of specific thalamic nuclei. Analysis of magnetic resonance images (MRI) of the head showed that the centre of ischemic necrosis particularly involved the intralaminar thalamic nuclei and a small part of the rostral mesencephalon. The findings support the previously suggested involvement of cortico-thalamo-mesencephalic circuitry in the initiation of motor responses, and the association of the non-specific thalamic nuclei with the appearance of generalized epileptiform phenomena in cases of reduced vigilance.
Topics: Adult; Amnesia; Cerebral Infarction; Electroencephalography; Humans; Magnetic Resonance Imaging; Male; Mutism; Necrosis; Paralysis; Thalamus; Tomography, X-Ray Computed
PubMed: 8836973
DOI: 10.1016/s0022-510x(96)00026-3 -
The Canadian Journal of Neurological... Aug 1985We report the case of a patient with idiopathic aqueductal stenosis and hydrocephalus who had several episodes of akinetic mutism, each preceded by shunt malfunction,...
We report the case of a patient with idiopathic aqueductal stenosis and hydrocephalus who had several episodes of akinetic mutism, each preceded by shunt malfunction, that resolved with shunt revision. She also developed a parkinson's syndrome resistant to shunt revision but responsive to antiparkinsonian medications. The parkinson's syndrome and the episodes of akinetic mutism may be related to a reduction of dopaminergic input to the striatum and to the cingulate and frontal cortex brought about or worsened by ventricular dilatation.
Topics: Adult; Akinetic Mutism; Brain Diseases; Cerebral Aqueduct; Cerebral Ventriculography; Cerebrospinal Fluid Shunts; Constriction, Pathologic; Female; Humans; Hydrocephalus; Parkinson Disease; Tomography, X-Ray Computed
PubMed: 3876872
DOI: 10.1017/s0317167100047119