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Journal of Cutaneous Pathology Jan 2017The diagnosis of primary scalp alopecia remains one of the most challenging fields in dermatopathology. In this review, we would like to connect the established... (Review)
Review
The diagnosis of primary scalp alopecia remains one of the most challenging fields in dermatopathology. In this review, we would like to connect the established classification of primary alopecia into scarring (cicatricial) and non-scarring (non-cicatricial) with current concepts. We introduce a simplified pathway for the diagnosis of the most common causes of alopecia, including a discussion of tissue processing techniques and use of immunohistochemistry.
Topics: Alopecia; Cicatrix; Female; Humans; Male; Scalp
PubMed: 27682637
DOI: 10.1111/cup.12822 -
International Journal of Dermatology Jan 2023
Topics: Humans; Scalp; Alopecia; Hair
PubMed: 35717593
DOI: 10.1111/ijd.16304 -
International Journal of Dermatology Feb 2018
Topics: Alopecia; Female; Humans; Traction; Young Adult
PubMed: 29265342
DOI: 10.1111/ijd.13846 -
Dermatologic Clinics Oct 1996Scarring alopecias are of diverse etiology and pathogenesis. They may be histologically classified as primary or secondary, depending on involvement of reticular dermis.... (Review)
Review
Scarring alopecias are of diverse etiology and pathogenesis. They may be histologically classified as primary or secondary, depending on involvement of reticular dermis. The most important primary scarring alopecias include pseudopelade, lichen planopilaris, and diffuse scarring of the vertex in African-Americans. The most important secondary scarring alopecias include folliculitis decalvans and late-stage lupus erythematosus.
Topics: Alopecia; Cicatrix; Diagnosis, Differential; Folliculitis; Hair Follicle; Humans; Lichenoid Eruptions; Lupus Erythematosus, Discoid
PubMed: 9238335
DOI: 10.1016/s0733-8635(05)70403-4 -
Dermatologic Clinics Jul 1987The scarring alopecias are a diverse group of diseases characterized by the combination of follicular destruction and dermal scarring. In this article we divide scarring... (Review)
Review
The scarring alopecias are a diverse group of diseases characterized by the combination of follicular destruction and dermal scarring. In this article we divide scarring alopecias into three broad categories, pediatric diseases, perifollicular lymphocytic diseases, and folliculopustular diseases, and discuss selected entities from each category.
Topics: Adult; Alopecia; Child; Cicatrix; Female; Humans; Male; Middle Aged
PubMed: 3301117
DOI: No ID Found -
Journal of Cosmetic Dermatology Nov 2021Vitamin D, a vitamin and hormone, plays an important role in dermatology and dermatotherapeutics, due to its anti-inflammatory and immunomodulatory properties, and... (Review)
Review
BACKGROUND
Vitamin D, a vitamin and hormone, plays an important role in dermatology and dermatotherapeutics, due to its anti-inflammatory and immunomodulatory properties, and regulation of keratinocyte differentiation and proliferation. It also affects the hair cycle, and its role in hair loss is under constant research.
OBJECTIVES
This review aims to give a brief overview of vitamin D biology within the hair follicle, role in the etiopathogenesis, and rationale for supplementation in various alopecias.
METHODS
A PubMed literature search was performed to review relevant current literature and studies investigating the role of vitamin D in the etiopathogenesis, as a supplement and a potential therapeutic modality in hair loss.
RESULTS AND CONCLUSION
Vitamin D is intricately involved in various signaling pathways of growth and differentiation of hair follicles. Most studies show an inverse relationship between serum vitamin D levels and non-scarring alopecias such as telogen effluvium, androgenetic alopecia, alopecia areata, and trichotillomania. Vitamin D deficiency is also associated with scarring alopecia. However, conclusive studies to demonstrate the benefit of vitamin D administration in correcting hair loss and managing these conditions are lacking. Hence, further studies are needed before vitamin D can be routinely recommended as a treatment modality in these conditions.
Topics: Alopecia; Alopecia Areata; Hair Follicle; Humans; Trichotillomania; Vitamin D; Vitamins
PubMed: 34553483
DOI: 10.1111/jocd.14421 -
FP Essentials Jun 2022Alopecia affects men and women and can result in significant distress for patients. Alopecias can be categorized as nonscarring or scarring. Nonscarring alopecias...
Alopecia affects men and women and can result in significant distress for patients. Alopecias can be categorized as nonscarring or scarring. Nonscarring alopecias include male and female pattern alopecias, alopecia areata, telogen effluvium, traction alopecia, trichotillomania, and tinea capitis. Scarring alopecias include central centrifugal cicatricial alopecia, lichen planopilaris, frontal fibrosing alopecia, discoid lupus erythematosus, dissecting cellulitis of the scalp, folliculitis decalvans, and acne keloidalis nuchae. Evaluation of patients with alopecia involves assessment of the duration and distribution of hair loss, associated scalp symptoms, and associated conditions. Clinical examination of the hair and scalp may include a hair pull test, tug test, hair mount (ie, trichogram), dermoscopy, laboratory tests, and/or scalp biopsy, depending on the suspected etiology. Hair regrowth cannot occur in established lesions of scarring alopecia, so early identification and prompt initiation of treatment are critical in these cases. Patients with suspected or confirmed alopecias, alopecia areata, or alopecias refractory to treatment may benefit from referral to a dermatologist.
Topics: Alopecia Areata; Cicatrix; Female; Hair; Humans; Lichen Planus; Male
PubMed: 35679467
DOI: No ID Found -
Cutis Jan 2003Traction alopecia is traumatic hair loss secondary to the application of tensile forces to scalp hair. This condition can be classified as marginal or nonmarginal. In... (Review)
Review
Traction alopecia is traumatic hair loss secondary to the application of tensile forces to scalp hair. This condition can be classified as marginal or nonmarginal. In either case, the induced trauma, often the result of cultural, social, and cosmetic practices, is unintentional. Initially, hair loss is reversible; however, permanent alopecia may result from chronic traction.
Topics: Alopecia; Child; Humans; Traction
PubMed: 12553624
DOI: No ID Found -
The Journal of Investigative Dermatology Jun 1973
Review
Topics: Abnormalities, Multiple; Adolescent; Adult; Age Factors; Alopecia; Alopecia Areata; Child; Child, Preschool; Chromosome Aberrations; Ectodermal Dysplasia; Female; Genes, Recessive; Hair; Humans; Infant; Male; Middle Aged; Scalp; Sex Chromosomes; Syndrome
PubMed: 4581946
DOI: 10.1111/1523-1747.ep12702937 -
Journal of Paediatrics and Child Health Nov 2022
Topics: Animals; Moths; Alopecia; Diagnosis, Differential
PubMed: 36371624
DOI: 10.1111/jpc.1_15861