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Analytical and Bioanalytical Chemistry Mar 2011
Topics: Art; Chemistry, Analytic; Culture
PubMed: 21271238
DOI: 10.1007/s00216-011-4672-5 -
International Anesthesiology Clinics 1987
Topics: Chemistry, Analytic; Forecasting; History, 20th Century; Humans; Oximetry
PubMed: 3323069
DOI: 10.1097/00004311-198702540-00009 -
Organic & Biomolecular Chemistry Feb 2015MicroRNA (miRNA) detection is of considerable significance in both disease diagnosis and in the study of miRNA function. The importance of miRNA itself is due to the... (Review)
Review
MicroRNA (miRNA) detection is of considerable significance in both disease diagnosis and in the study of miRNA function. The importance of miRNA itself is due to the complicated regulatory functions it plays in various life processes and its close relationship with some diseases. Traditional methods for miRNA detection do not meet the current demands, so various novel methods have been developed with a special focus on sensitivity and specificity. Herein, we summarize and discuss the newly developed miRNA detection methods.
Topics: Chemistry Techniques, Analytical; Chemistry, Analytic; MicroRNAs
PubMed: 25574760
DOI: 10.1039/c4ob02104e -
Analytical Chemistry Nov 2022A major obstacle for reusing and integrating existing data is finding the data that is most relevant in a given context. The primary metadata resource is the scientific...
A major obstacle for reusing and integrating existing data is finding the data that is most relevant in a given context. The primary metadata resource is the scientific literature describing the experiments that produced the data. To stimulate the development of natural language processing methods for extracting this information from articles, we have manually annotated 100 recent open access publications in Analytical Chemistry as semantic graphs. We focused on articles mentioning mass spectrometry in their experimental sections, as we are particularly interested in the topic, which is also within the domain of several ontologies and controlled vocabularies. The resulting gold standard dataset is publicly available and directly applicable to validating automated methods for retrieving this metadata from the literature. In the process, we also made a number of observations on the structure and description of experiments and open access publication in this journal.
Topics: Semantics; Natural Language Processing; Research Design; Chemistry, Analytic
PubMed: 36281827
DOI: 10.1021/acs.analchem.2c03565 -
Bioanalysis Jun 2009
Topics: Chemistry, Analytic; Clinical Trials as Topic; Developing Countries; Drug Evaluation, Preclinical; Humans; Monitoring, Physiologic; Outsourced Services
PubMed: 21083144
DOI: 10.4155/bio.09.54 -
Talanta Oct 2011
Topics: Chemistry, Analytic; History, 19th Century; History, 20th Century; Nobel Prize
PubMed: 22063505
DOI: 10.1016/j.talanta.2011.09.007 -
Analytical and Bioanalytical Chemistry Aug 2005
Topics: Chemistry, Analytic; Faculty; Germany; History, 20th Century; History, 21st Century
PubMed: 15940447
DOI: 10.1007/s00216-005-3299-9 -
Analytical and Bioanalytical Chemistry Oct 2003
Topics: Biosensing Techniques; Chemistry, Analytic; Specimen Handling
PubMed: 14570077
DOI: 10.1007/s00216-003-2190-9 -
TheScientificWorldJournal Jul 2009Modern scientific endeavour is increasingly delivered within an interdisciplinary framework. Analytical environmental chemistry is a long-standing example of an...
Modern scientific endeavour is increasingly delivered within an interdisciplinary framework. Analytical environmental chemistry is a long-standing example of an interdisciplinary approach to scientific research where value is added by the close cooperation of different disciplines. This editorial piece discusses the rise of environmental analytical chemistry as an interdisciplinary activity and outlines the scope of the Analytical Chemistry and the Environmental Chemistry domains of TheScientificWorldJOURNAL (TSWJ), and the appropriateness of TSWJ's domain format in covering interdisciplinary research. All contributions of new data, methods, case studies, and instrumentation, or new interpretations and developments of existing data, case studies, methods, and instrumentation, relating to analytical and/or environmental chemistry, to the Analytical and Environmental Chemistry domains, are welcome and will be considered equally.
Topics: Chemistry, Analytic; Environmental Monitoring; Environmental Pollutants; Environmental Pollution; Research; Research Design
PubMed: 19578710
DOI: 10.1100/tsw.2009.78 -
Sensors (Basel, Switzerland) Dec 2022Sucrose is a primary metabolite in plants, a source of energy, a source of carbon atoms for growth and development, and a regulator of biochemical processes. Most of the... (Review)
Review
Sucrose is a primary metabolite in plants, a source of energy, a source of carbon atoms for growth and development, and a regulator of biochemical processes. Most of the traditional analytical chemistry methods for sucrose quantification in plants require sample treatment (with consequent tissue destruction) and complex facilities, that do not allow real-time sucrose quantification at ultra-low concentrations (nM to pM range) under in vivo conditions, limiting our understanding of sucrose roles in plant physiology across different plant tissues and cellular compartments. Some of the above-mentioned problems may be circumvented with the use of bio-compatible ligands for molecular recognition of sucrose. Nevertheless, problems such as the signal-noise ratio, stability, and selectivity are some of the main challenges limiting the use of molecular recognition methods for the in vivo quantification of sucrose. In this review, we provide a critical analysis of the existing analytical chemistry tools, biosensors, and synthetic ligands, for sucrose quantification and discuss the most promising paths to improve upon its limits of detection. Our goal is to highlight the criteria design need for real-time, in vivo, highly sensitive and selective sucrose sensing capabilities to enable further our understanding of living organisms, the development of new plant breeding strategies for increased crop productivity and sustainability, and ultimately to contribute to the overarching need for food security.
Topics: Sucrose; Carbon; Chemistry, Analytic; Crop Production; Recognition, Psychology
PubMed: 36502213
DOI: 10.3390/s22239511