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Medicina Cutanea Ibero-latino-americana 1981A case of solitary angiokeratoma is reported, in a 50 years old patient. It occurred in abdominal skin six months prior to consultation. There was history of traumatism...
A case of solitary angiokeratoma is reported, in a 50 years old patient. It occurred in abdominal skin six months prior to consultation. There was history of traumatism preceding the onset of the lesion. Treatment was surgical excision. Histological study confirmed the diagnosis. A bibliographic revision is made, with some considerations on the nature of this lesion.
Topics: Abdomen; Angiokeratoma; Humans; Male; Middle Aged; Skin Neoplasms
PubMed: 7024676
DOI: No ID Found -
Dermatologica 1978A female of 66 who presented with long-standing pruritus vulvae showed angiokeratoma of the vulva as an incidental finding. This benign tumour is uncommon and in a...
A female of 66 who presented with long-standing pruritus vulvae showed angiokeratoma of the vulva as an incidental finding. This benign tumour is uncommon and in a survey of 150 patients over 50 years old (mean age 76.9), no further example was found.
Topics: Aged; Angiokeratoma; Female; Humans; Pruritus Vulvae; Vulvar Neoplasms
PubMed: 640106
DOI: 10.1159/000250931 -
International Journal of Dermatology Jun 2019Angiokeratoma corporis diffusum are benign capillary malformations typically associated with Fabry disease and other lysosomal storage disorders. Only in a few cases... (Review)
Review
INTRODUCTION
Angiokeratoma corporis diffusum are benign capillary malformations typically associated with Fabry disease and other lysosomal storage disorders. Only in a few cases they appear in healthy individuals.
METHODS AND CASE
We carried out an exhaustive review of the literature on angiokeratomas and their main clinical, dermoscopy and histological features. Additionally, we reviewed the cases of healthy subjects illustrating the limitations of each case and comparing these results with our case.
DISCUSSION
Angiokeratoma corporis diffusum is mostly related to Fabry disease and other lysosomal storage disorders. However, some cases may occur in apparently healthy individuals. Therefore, there is a increasing interest in its etiology, pathogenesis and clinical evaluation.
CONCLUSION
This is an academic-clinical review on angiokeratomas and their main implications in daily dermatological practice. Additionally, we report the first case in the literature of angiokeratoma corporis diffusum in a healthy patient with up-to-date laboratory methods currently available. The clinician should remember that not all angiokeratoma corporis diffusum occurs with lysosomal storage disorders.
Topics: Adult; Angiokeratoma; Biopsy; Dermoscopy; Diagnosis, Differential; Fabry Disease; Female; Humans; Skin; Skin Neoplasms
PubMed: 30656678
DOI: 10.1111/ijd.14330 -
North Carolina Medical Journal Feb 1990
Topics: Adult; Angiokeratoma; Dermatology; History, 19th Century; History, 20th Century; Humans; Male; Scrotum; Skin Neoplasms; United States
PubMed: 2407964
DOI: No ID Found -
Helvetica Medica Acta Dec 1967
Topics: Adolescent; Adult; Angiokeratoma; Biopsy; Blood Vessels; Child; Child, Preschool; Corneal Opacity; Electrocardiography; Female; Fever; Humans; Kidney; Lipid Metabolism, Inborn Errors; Male; Middle Aged; Pedigree; Proteinuria; Sex Chromosomes; Skin
PubMed: 5592081
DOI: No ID Found -
Dermatologica 1984An interesting expression of angiokeratoma corporis naeviforme highlighting its unusual features is described.
An interesting expression of angiokeratoma corporis naeviforme highlighting its unusual features is described.
Topics: Angiokeratoma; Diagnosis, Differential; Hemangioma; Humans; Male; Middle Aged; Skin; Skin Neoplasms
PubMed: 6714505
DOI: 10.1159/000249687 -
The Journal of Dermatology Feb 2000
Topics: Adult; Angiokeratoma; Genital Neoplasms, Male; Humans; Male; Scrotum; Skin Neoplasms; Tongue Neoplasms
PubMed: 10721665
DOI: 10.1111/j.1346-8138.2000.tb02137.x -
The Journal of Dermatology Apr 1993A 5-year-old Japanese boy visited our clinic for treatment of a dark bluish papulonodular lesion on his right thigh. The histopathology of the lesion indicated...
A 5-year-old Japanese boy visited our clinic for treatment of a dark bluish papulonodular lesion on his right thigh. The histopathology of the lesion indicated angiokeratoma corporis circumscriptum naeviforme. Topical antibiotics were prescribed for occasional bleeding from the site. Frequent bleeding started in April of 1992, when erythema and itching were observed around the angiokeratoma. Histopathology of the lesion showed heavy lymphoid cell infiltration around dilated capillaries and irregular acanthosis engulfing dilated capillaries. Interestingly, there were confined masses of red blood cells in the epidermal layer as well as both in and on the horny layer. This is a feature of transepidermal elimination. This transepidermal elimination appeared to be triggered or enhanced by the concomitant contact dermatitis due to topical antibiotics. To the best of our knowledge, this is the first report of angiokeratoma in which the angiokeratoma itself reduced in size through transepidermal elimination, possibly caused by contact dermatitis.
Topics: Angiokeratoma; Capillaries; Child, Preschool; Dermatitis, Contact; Epidermis; Erythrocytes; Humans; Male; Neomycin; Povidone-Iodine; Skin Neoplasms
PubMed: 8315116
DOI: 10.1111/j.1346-8138.1993.tb03870.x -
Archives of Dermatology Mar 1981Three patients with solitary angiokeratomas, two of the circumscribed type (Fabry) and one of the Mibelli type, are described to show that when extensive thromboses...
Three patients with solitary angiokeratomas, two of the circumscribed type (Fabry) and one of the Mibelli type, are described to show that when extensive thromboses develop in an angiokeratoma, this nodular bluish-black lesion may clinically simulate a nodular melanoma.
Topics: Adult; Aged; Angiokeratoma; Child; Diagnosis, Differential; Fabry Disease; Female; Humans; Male; Melanoma; Skin Neoplasms; Thrombosis
PubMed: 6782953
DOI: No ID Found -
Journal of Experimental Therapeutics &... 2015The aim of this study is to present a very rare dermatologic condition of the vulva. Angiokeratoma is a benign dilation of ectatic thin-walled blood vessels and...
The aim of this study is to present a very rare dermatologic condition of the vulva. Angiokeratoma is a benign dilation of ectatic thin-walled blood vessels and congested capillaries in the superficial dermal layer of skin. It occurs predominantly in men and extremely rare in women. Angiokeratoma presents as single or multiple papular lesions on the vulva with smooth or verrucous surface. These lesions are easily confused with infectious disease, inflammatory lesions, and epithelial tumors. In this report, we presented a 42 year old unmarried woman who was admitted to our clinic with complaints of two papuler lesions of the right labium majus with vaginal discharge, vulvar pruritis, and vulvar edema. She had been previously treated with different local or systemic antiinfectious agents and her screening tests for sexually transmitted disease were negative. The genital examination showed a very thinned, hyperemic and edematous vulvar skin with two lesions measured 0,5-1 cm in diameter on the right labium majus. The surface of the lesions was partly uneven and partly veined. A local excision was performed. Histological examination showed hyperkeratosis, papillomatosis and acanthosis with dilated vascular areas in the dermis and the specimen revealed angiokeratoma. In conclusion, we should be aware of this clinical entity to make the differential diagnosis of a lesion on the vulva.
Topics: Adult; Angiokeratoma; Biopsy; Diagnosis, Differential; Female; Humans; Predictive Value of Tests; Skin Neoplasms; Treatment Outcome; Vulvar Neoplasms
PubMed: 26259393
DOI: No ID Found