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The American Journal of Medicine Sep 2010
Topics: Abscess; Animals; Anthelmintics; Anus Diseases; Chronic Disease; Drainage; Endemic Diseases; Humans; Male; Mali; Middle Aged; Praziquantel; Proctoscopy; Recurrence; Schistosoma; Schistosomiasis; Tomography, X-Ray Computed; Treatment Outcome
PubMed: 20800133
DOI: 10.1016/j.amjmed.2010.01.034 -
Pediatrics Feb 2008
Topics: Abscess; Anti-Bacterial Agents; Anus Diseases; Diagnosis, Differential; Drainage; Granulomatous Disease, Chronic; Humans; Immunocompromised Host; Infant
PubMed: 18245438
DOI: 10.1542/peds.2007-3276 -
Gastroenterology Nursing : the Official... 2009Anal condyloma acuminatum is a human papillomavirus (HPV) that affects the mucosa and skin of the anorectum and genitalia. Anal condyloma acuminatum is the most commonly...
Anal condyloma acuminatum is a human papillomavirus (HPV) that affects the mucosa and skin of the anorectum and genitalia. Anal condyloma acuminatum is the most commonly diagnosed sexually transmitted disease in the United States. To date, there are more than 100 HPV types, with HPV-6, HPV-10, and HPV-11 predominately found in the anogenital region and causing approximately 90% of genital warts. Risk factors for anal condyloma acuminatum include multiple sex partners, early coital age, anal intercourse, and immunosuppression. Transmission occurs by way of skin-to-skin contact through sexual intercourse, oral sex, anal sex, or other contact involving the genital area. The virus may remain latent for months to years until specific mechanisms cause production of viral DNA, leading to the presentation of anal condyloma acuminatum.Patients with anal condyloma acuminatum may be asymptomatic or present with presence of painless bumps, itching, and discharge or bleeding. It is not uncommon to have involvement of more than one area, and multiple lesions may also be present and extend into the anal canal or rectum. To date, there is no serologic testing or culture to detect anal condyloma acuminatum; therefore, diagnosis is made clinically or by detection of HPV DNA. Multiple factors determine the choice of treatment, which may range from patient-applied medications to surgical intervention. Despite treatment choice, recurrence rates are high, indicating the importance of patient education on prevention of HPV infection and reinfection. Unfortunately, at this time, no cure exists for anal condyloma acuminatum; however, recently Gardasil and Cervarix (in Australia only) vaccines have become available and are showing promising results.
Topics: Adolescent; Adult; Anus Diseases; Child; Condylomata Acuminata; Female; Humans; Male; Papillomavirus Vaccines; Patient Education as Topic; Risk Factors; Young Adult
PubMed: 19820442
DOI: 10.1097/SGA.0b013e3181b85d4e -
Der Hautarzt; Zeitschrift Fur... Jun 2015Sexually transmitted infections (STIs) are increasingly observed in men who have sex with men (MSM), which is associated with the success in the antiretroviral treatment... (Review)
Review
BACKGROUND
Sexually transmitted infections (STIs) are increasingly observed in men who have sex with men (MSM), which is associated with the success in the antiretroviral treatment of HIV infection. Additionally, in heterosexuals, anal intercourse is more prevalent than previously assumed. Thus, anorectal manifestations of STIs are not a rare condition.
OBJECTIVES
This review will focus on the clinical picture, diagnosis and therapy of frequent STIs involving the anorectal region.
CONCLUSIONS
Due to localisation and frequent asymptomatic course, STIs in this region often pose diagnostic problems. Anorectal manifestations of STIs consist of tumorous masses, ulcers or proctitis and may be misdiagnosed as malignancy or inflammatory bowel disease. Herpes simplex and syphilis primarily show ulcerations and may involve the perianal region, whereas gonorrhoea and lymphogranuloma venereum mainly cause proctitic symptoms with exsudation. Because of commonly occurring coinfections a complete diagnostic workup concerning other STIs should be performed.
Topics: Anus Diseases; Coinfection; Diagnosis, Differential; Female; Homosexuality, Male; Humans; Male; Rectal Diseases; Sexual Behavior; Sexually Transmitted Diseases
PubMed: 25898890
DOI: 10.1007/s00105-015-3627-8 -
Clinical and Experimental Dermatology Nov 2001Lichen sclerosus (LS) is a skin condition that affects genital and extra genital epithelia in both males and females of all ages and it may occur in association with... (Review)
Review
Lichen sclerosus (LS) is a skin condition that affects genital and extra genital epithelia in both males and females of all ages and it may occur in association with other autoimmune disease. Currently, the first line effective treatment is an ultra-potent topical corticosteroid. The long-term sequelae of LS include scarring, malignancy, which is rare, and psychosexual disfunction, which is common.
Topics: Administration, Topical; Anti-Inflammatory Agents; Anus Diseases; Clobetasol; Female; Glucocorticoids; Humans; Lichen Sclerosus et Atrophicus; Male; Penile Diseases; Sexual Dysfunctions, Psychological; Vulvar Diseases
PubMed: 11722445
DOI: 10.1046/j.1365-2230.2001.00907.x -
Journal of Crohn's & Colitis Jan 2021Perianal Crohn's disease [CD] places a considerable burden on patients' quality of life and is complex to treat. Despite its impact and high frequency, few studies have...
BACKGROUND AND AIMS
Perianal Crohn's disease [CD] places a considerable burden on patients' quality of life and is complex to treat. Despite its impact and high frequency, few studies have investigated the incidence and disease course of perianal CD. The aim of this study was to assess the incidence and disease course of perianal CD in adult patients throughout a 19-year period.
METHODS
The cohort comprised all individuals aged 18 years or older who were diagnosed with CD in Denmark between January 1, 1997, and December 31, 2015, according to the National Patient Registry [NPR].
RESULTS
A total of 1812 [19%] out of 9739 patients with CD were found to have perianal CD. Perianal fistulas were the most common manifestation, accounting for 943 [52%] cases. The incidence of perianal CD remained stable over time. Patients with perianal CD were found to have an increased risk of undergoing major abdominal surgery compared with patients without perianal CD (hazard ratio: 1.51, 95% confidence interval [CI]: 1.40 to 1.64, pā <0.001) in a multivariate Cox regression analysis. The incidence rate ratios of anal and rectal cancer in perianal CD patients were 11.45 [95% CI: 4.70 to 27.91, pā <0.001] and 2.29 [95% CI: 1.25 to 4.20, pā =ā 0.006], respectively, as compared with non-IBD matched controls.
CONCLUSIONS
In this nationwide study, 19% of CD patients developed perianal disease. Patients with perianal CD were at increased risk of undergoing major surgery compared with non-perianal CD patients. The risk of anal and rectal cancer was increased in patients with perianal CD compared with non-IBD matched controls.
PODCAST
This article has an associated podcast which can be accessed at https://academic.oup.com/ecco-jcc/pages/podcast.
Topics: Adult; Anus Diseases; Crohn Disease; Denmark; Digestive System Surgical Procedures; Female; Humans; Incidence; Male; Quality of Life; Rectal Neoplasms; Registries; Risk Assessment
PubMed: 32582937
DOI: 10.1093/ecco-jcc/jjaa118 -
Diseases of the Colon and Rectum Oct 1985A group of 86 patients with anorectal Crohn's disease were followed up from ten to 40 years to determine the course of the disease and the number of patients who later...
A group of 86 patients with anorectal Crohn's disease were followed up from ten to 40 years to determine the course of the disease and the number of patients who later required proctectomy. The overall cumulative probability of avoiding proctectomy was 91.6 percent at ten years and 82.5 percent at 20 years. Resection of all proximal Crohn's disease did not ameliorate the anorectal disease, except in patients who had all proximal disease removed and had no recurrence.
Topics: Adolescent; Adult; Aged; Anus Diseases; Child; Crohn Disease; Female; Follow-Up Studies; Humans; Male; Middle Aged; Rectal Diseases; Recurrence; Reoperation; Time Factors
PubMed: 4053875
DOI: 10.1007/BF02560279 -
Gastroenterology Nursing : the Official... Dec 1992Anorectal manometry is used in the treatment of complex anorectal disorders, such as fecal incontinence and intractable constipation. In a 3-year period at one...
Anorectal manometry is used in the treatment of complex anorectal disorders, such as fecal incontinence and intractable constipation. In a 3-year period at one institution 308 anorectal manometries were performed. A total of 168 procedures were performed for complaints of fecal incontinence, 77 for constipation, and the remainder for a variety of anorectal disorders. Anorectal manometry in those under 20 years of age was performed most often to differentiate Hirschsprung disease from functional constipation, as well as to provide a differential diagnosis related to congenital anorectal anomalies. In patients between the ages of 21 and 40 years, evaluation of fecal incontinence (especially obstetrical injuries) was most significant. Fecal incontinence accounted for twice the number of anorectal manometries for those between the ages of 41 and 60. For those over 60 years of age, the majority of anorectal manometries were done for fecal incontinence rather than for constipation (nearly a 4:1 ratio). Anorectal manometry is a valuable physiologic adjunct in the evaluation, diagnosis, and treatment of organic and functional disorders of the anorectum.
Topics: Adolescent; Adult; Anus Diseases; Child; Child, Preschool; Female; Humans; Infant; Male; Manometry; Middle Aged; Nursing Care; Rectal Diseases
PubMed: 1472555
DOI: 10.1097/00001610-199212000-00006 -
Giornale Italiano Di Dermatologia E... Oct 2018
Topics: Anus Diseases; Crohn Disease; Female; Humans; Perineum; Ulcer; Young Adult
PubMed: 28704991
DOI: 10.23736/S0392-0488.17.05677-2 -
Diseases of the Colon and Rectum May 2018
Topics: Anal Canal; Anus Diseases; Biopsy; Colonoscopy; Crohn Disease; Defecation; Humans; Practice Guidelines as Topic
PubMed: 29624546
DOI: 10.1097/DCR.0000000000001079