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The Journal of Infection Jan 1999Systemic infection caused by Arcanobacterium haemolyticum is uncommon. We report a case of empyema and bacteraemia caused by this organism concomitant with Mycoplasma...
Systemic infection caused by Arcanobacterium haemolyticum is uncommon. We report a case of empyema and bacteraemia caused by this organism concomitant with Mycoplasma pneumoniae infection.
Topics: Actinomycetaceae; Actinomycetales Infections; Adult; Amoxicillin; Bacteremia; Empyema, Pleural; Erythromycin; Humans; Male; Mycoplasma pneumoniae; Pneumonia, Mycoplasma
PubMed: 10090506
DOI: 10.1016/s0163-4453(99)90028-2 -
New Microbes and New Infections Jul 2017Herein we report the main characteristics of strain Marseille-P3248 (=CSUR P3248) isolated from a urine sample of a 54-day-old girl with rotavirus gastroenteritis.
Herein we report the main characteristics of strain Marseille-P3248 (=CSUR P3248) isolated from a urine sample of a 54-day-old girl with rotavirus gastroenteritis.
PubMed: 28480045
DOI: 10.1016/j.nmni.2017.03.003 -
European Journal of Clinical... Sep 2007Arcanobacterium pyogenes is a rare cause of infection in humans, mostly related to living in rural areas and to contacts with animals. We describe a case of fatal... (Review)
Review
Arcanobacterium pyogenes is a rare cause of infection in humans, mostly related to living in rural areas and to contacts with animals. We describe a case of fatal Arcanobacterium pyogenes endocarditis, confirmed by DNA sequencing, in a patient without typical epidemiological exposure.
Topics: Actinomycetaceae; Animals; DNA, Bacterial; Endocarditis, Bacterial; Fatal Outcome; Humans; Male; Middle Aged; Sequence Analysis, DNA
PubMed: 17610093
DOI: 10.1007/s10096-007-0354-9 -
Revista Argentina de Microbiologia 2020We report the case of a twenty-year-old immunocompetent male patient presenting to the emergency room with pharyngitis and fever. Blood cultures were drawn and...
We report the case of a twenty-year-old immunocompetent male patient presenting to the emergency room with pharyngitis and fever. Blood cultures were drawn and Arcanobacterium haemolyticum (rough biotype) was recovered. The presence of the arcanolysin gene was investigated at the molecular level and the upstream region was amplified and sequenced in order to correlate it with the smooth or rough biotype. Although the isolate was susceptible to penicillin, vancomycin and gentamicin, empirical treatments first with amoxicillin/clavulanic acid (1g/12h) and then with ceftriaxone (1g/12h) failed and the infection evolved to sepsis. Finally, treatment with vancomycin (1g/12h) plus piperacillin/tazobactam (4.5g/8h) was effective. Lemierre's syndrome was ruled out. To the best of our knowledge, this is the first case of bacteremia by A. haemolyticum reported in Argentina.
Topics: Actinomycetales Infections; Adult; Arcanobacterium; Bacteremia; Humans; Male; Sepsis; Young Adult
PubMed: 32201068
DOI: 10.1016/j.ram.2020.01.001 -
BMC Infectious Diseases Sep 2005Arcanobacterium haemolyticum has an established role in the etiology of human pharyngitis. There are increasing reports of systemic infections caused by this organism....
Arcanobacterium haemolyticum has an established role in the etiology of human pharyngitis. There are increasing reports of systemic infections caused by this organism. From India, we report the first case of Arcanobacterium haemolyticum causing pyothorax in an immunocompetent adolescent male patient. The probable mode of infection is also discussed. The role of A. hemolyticum as an animal pathogen needs further study.
Topics: Actinomycetaceae; Adult; Anti-Bacterial Agents; Empyema, Pleural; Gram-Positive Bacterial Infections; Humans; Male
PubMed: 16144543
DOI: 10.1186/1471-2334-5-68 -
IDCases 2021can cause deep infections, including osteomyelitis. In this study, an automated system misidentified this causal agent as species but 16 s rRNA sequencing correctly...
can cause deep infections, including osteomyelitis. In this study, an automated system misidentified this causal agent as species but 16 s rRNA sequencing correctly identified it as . Recognizing the capability of to establish the disease is of great importance to enable accurate diagnosis and begin the suitable antibiotic therapy. Here we present the first case of successfully treated infective osteomyelitis in a 64-year-old Saudi patient with diabetes mellitus type 2 and review the characteristics of this seldom pathogenic agent.
PubMed: 34026534
DOI: 10.1016/j.idcr.2021.e01139 -
Scandinavian Journal of Infectious... 1994Arcanobacterium haemolyticum was recovered from 0.5% of throat cultures of 3,922 patients seeking medical attention because of sore throat. Most of the patients positive... (Comparative Study)
Comparative Study
Arcanobacterium haemolyticum was recovered from 0.5% of throat cultures of 3,922 patients seeking medical attention because of sore throat. Most of the patients positive for A. haemolyticum were 15-25 years old, and had fever (80%), lymphadenopathy (67%), pharyngeal exudate (69%) or skin rash (23%). In this age group, 2% of the throat cultures proved positive for A. haemolyticum. All A. haemolyticum strains were susceptible to penicillin, erythromycin, cephalexin and clindamycin, but resistant to trimethoprim/sulphamethoxazole. In half of the patients with A. haemolyticum it was the only bacterial pathogen isolated, while in the remainder, beta-haemolytic streptococci were also detected. As expected, beta-haemolytic streptococci were much more frequent than A. haemolyticum in the throat cultures.
Topics: Actinomycetaceae; Actinomycetales Infections; Adolescent; Adult; Child; Child, Preschool; Drug Resistance, Microbial; Female; Finland; Humans; Incidence; Infant; Male; Microbial Sensitivity Tests; Pharyngitis; Streptococcal Infections
PubMed: 7939427
DOI: 10.3109/00365549409011796 -
Veterinary Microbiology Apr 2020The present study was designed to identify nine Arcanobacterium phocae strains isolated from cases of mink dermatitis of a single farm in Finland and characterize the...
The present study was designed to identify nine Arcanobacterium phocae strains isolated from cases of mink dermatitis of a single farm in Finland and characterize the strains for epidemiological relationships. All nine strains and previously described A. phocae used for comparative purposes were identified and further characterized phenotypically, by matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS), by Fourier Transform Infrared Spectroscopy (FT-IR) and genotypically by detection of phocaelysin encoding gene phl with a previously developed loop-mediated isothermal amplification (LAMP) assay and by sequencing 16S rRNA gene and gene phl, the elongation factor tu encoding gene tuf and the β subunit of bacterial RNA polymerase encoding gene rpoB. Genetic relatedness among isolates was determined using whole-genome single nucleotide polymorphism (wgSNP) analysis. The wgSNP results, partly the MALDI-TOF MS and FT-IR analyses and sequencing of the genes, revealed that the nine A. phocae strains recovered from a single farm showed close sequence similarities among each other and differed from previously investigated A. phocae strains isolated from other farms and animals in Finland and from the A. phocae type strain. This indicated a close epidemiological relationship of the A. phocae strains isolated from a single farm and that the nine A. phocae strains of the present study might have developed from a common ancestor.
Topics: Actinomycetales Infections; Animals; Arcanobacterium; Dermatitis; Farms; Finland; Genome, Bacterial; Genotype; Mink; Phenotype; Phylogeny; Polymorphism, Single Nucleotide; RNA, Ribosomal, 16S; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectroscopy, Fourier Transform Infrared
PubMed: 32273004
DOI: 10.1016/j.vetmic.2020.108618 -
The Journal of Vascular Access Nov 2015
Topics: Actinomycetales Infections; Anti-Bacterial Agents; Arcanobacterium; Bacteremia; Catheterization, Central Venous; Catheters, Indwelling; Central Venous Catheters; Equipment Design; Humans; Kidney Failure, Chronic; Male; Microbial Sensitivity Tests; Middle Aged; Prosthesis-Related Infections; Renal Dialysis; Time Factors; Treatment Outcome
PubMed: 26109538
DOI: 10.5301/jva.5000434 -
Surgical Infections Jun 2013Arcanobacterium haemolyticum can cause severe systemic infections and sepsis. Thus, accurate and timely identification of the organism is essential.
BACKGROUND
Arcanobacterium haemolyticum can cause severe systemic infections and sepsis. Thus, accurate and timely identification of the organism is essential.
METHODS
Case report and review of the pertinent English-language literature.
CASE REPORT
A 74-year-old male underwent repetitive surgical debridement and grafting for a full-thickness ulcer on the plantar surface of the left foot. One week after the last debridement, the patient presented to the emergency department with fever, hypotension, and severe left foot pain. A radiograph showed a soft-tissue defect of the plantar aspect of the left midfoot with gas along the lateral aspect of the fifth metatarsal. A below-knee amputation was performed. Blood culture and intraoperative tissue specimens grew colonies that exhibited β-hemolysis on sheep blood agar and agglutinated with streptococcal B group antiserum. However, gram staining revealed that the organism was a gram-positive bacillus, and a reverse Christie, Atkins, Munch-Peterson (CAMP) test showed that the organism inhibited the β-hemolysis of Staphylococcus aureus on sheep blood agar. Biochemical testing identified the organism as A. haemolyticum.
CONCLUSIONS
It is important to investigate for A. haemolyticum when organisms with β-hemolytic activity react with group B streptococcal antiserum. Otherwise, A. haemolyticum can be mis-identified as group B Streptococcus or Listeria monocytogenes. This distinction is important clinically, because despite good in vitro activity of penicillin (a first-line antibiotic for group B Streptococcus infections), treatment failures have been reported when penicillin has been used for A. haemolyticum infections.
Topics: Actinomycetales Infections; Aged; Arcanobacterium; Arthropathy, Neurogenic; Bacteremia; Foot Ulcer; Humans; Male; Osteomyelitis
PubMed: 23581632
DOI: 10.1089/sur.2011.129