-
Documenta Ophthalmologica. Advances in... Feb 1973
Topics: Age Factors; Arcus Senilis; Birefringence; Cadaver; Cornea; Histocytochemistry; Humans; Lipid Metabolism; Lipid Metabolism, Inborn Errors; Lipids; Lipoproteins; Membranes; Microscopy, Polarization; Sclera; Staining and Labeling
PubMed: 4122363
DOI: 10.1007/BF00151805 -
Annals of Internal Medicine Feb 1968
Topics: Adolescent; Adult; Age Factors; Aged; Arcus Senilis; Black People; Cerebrovascular Disorders; Child; Child, Preschool; Cornea; Coronary Disease; Female; Humans; Hyperglycemia; Hypertension; Infant; Male; Middle Aged; Myocardial Infarction; Sex Factors; Terminology as Topic; United States; White People
PubMed: 5713918
DOI: 10.7326/0003-4819-68-2-345 -
The New England Journal of Medicine Jul 1973
Topics: Arcus Senilis; Cornea; Humans
PubMed: 4711354
DOI: 10.1056/NEJM197307192890322 -
British Medical Journal Feb 1965
Topics: Aging; Arcus Senilis; Body Height; Body Weight; Cholesterol; Cornea; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Statistics as Topic
PubMed: 14237926
DOI: 10.1136/bmj.1.5432.425 -
Indian Journal of Ophthalmology May 2022To evaluate corneal densitometry (CD) of patients with arcus senilis (AS) and its association with the serum lipid markers.
PURPOSE
To evaluate corneal densitometry (CD) of patients with arcus senilis (AS) and its association with the serum lipid markers.
METHODS
This is a cross-sectional, case-control study. The AS diagnosis was made clinically. Forty-five eyes of 45 patients with AS and 38 eyes of 38 age-matched control subjects with no noticeable AS were enrolled in the study. All participants underwent detailed ophthalmologic examination along with corneal Scheimpflug imaging with CD measurement. The evaluated serum lipid markers of the participants included total cholesterol, triglyceride, low-density lipoprotein (LDL), high-density lipoprotein (HDL), and very-low-density lipoprotein (VLDL). The Spearman correlation analysis was used to correlate the serum lipid values and the CD. P < 0.05 was defined as statistically significant.
RESULTS
The male to female ratio was 26/19 and 14/24 in the study and control groups, respectively (P = 0.057). The mean age was 59.56 ± 8.7 and 56.47 ± 8.6 years in the study and control groups, respectively (P = 0.117). The mean total CD values in the zones extending from 2 to 12 mm were higher in the study group than in the control group (P < 0.001). The serum HDL level was found to be significantly decreased in the study group compared to the control group (P = 0.048 and Z = -1.976). There was a significant positive correlation between the serum triglyceride level and the CD value of the outermost zone (10-12 mm) (r = 0.334 and P = 0.025).
CONCLUSION
The CD of patients with AS was found to increase not only in the peripheral zone but also in the cornea's paracentral zone compared to the healthy controls. The serum triglyceride level should give an insight into the intensity of arcus senilis. The serum HDL levels were decreased in patients with AS.
Topics: Aged; Arcus Senilis; Case-Control Studies; Cornea; Cross-Sectional Studies; Densitometry; Female; Humans; Male; Middle Aged; Triglycerides
PubMed: 35502026
DOI: 10.4103/ijo.IJO_2696_21 -
Indian Journal of Ophthalmology Oct 2019
Topics: Aged; Arcus Senilis; Cataract; Cataract Extraction; Cornea; Humans; Male; Visual Acuity
PubMed: 31546532
DOI: 10.4103/ijo.IJO_402_19 -
British Heart Journal Jul 1970The frequency and degree of arcus in relation to a number of attributes or risk factors were tested in 534 male patients of all ages with coronary heart disease....
The frequency and degree of arcus in relation to a number of attributes or risk factors were tested in 534 male patients of all ages with coronary heart disease. Frequency and degree of arcus were positively associated with age and with lifetime alcohol intake. Arcus was negatively associated with obesity. All other correlations proved negative. The link between precocious arcus senilis and coronary heart disease is discussed. This investigation failed to show any relation between the acknowledged high-grade coronary heart disease risk factors and arcus senilis. It is suggested that the relation between arcus and alcohol intake merits further investigation.
Topics: Adult; Age Factors; Aged; Alcohol Drinking; Arcus Senilis; Blood Pressure; Cornea; Coronary Disease; Glucose Tolerance Test; Humans; Lipids; Male; Middle Aged; Obesity; Skinfold Thickness; Smoking
PubMed: 5433305
DOI: 10.1136/hrt.32.4.449 -
Journal of Biomedical Physics &... Aug 2020Arcus Senilis (AS) appears as a white, grey or blue ring or arc in front of the periphery of the iris, and is a symptom of abnormally high cholesterol in patients under...
BACKGROUND
Arcus Senilis (AS) appears as a white, grey or blue ring or arc in front of the periphery of the iris, and is a symptom of abnormally high cholesterol in patients under 50 years old.
OBJECTIVE
This work proposes a deep learning approach to automatic recognition of AS in eye images.
MATERIAL AND METHODS
In this analytical study, a dataset of 191 eye images (130 normal, 61 with AS) was employed where ¾ of the data were used for training the proposed model and ¼ of the data were used for test, using a 4-fold cross-validation. Due to the limited amount of training data, transfer learning was conducted with AlexNet as the pretrained network.
RESULTS
The proposed model achieved an accuracy of 100% in classifying the eye images into normal and AS categories.
CONCLUSION
The excellent performance of the proposed model despite limited training set, demonstrate the efficacy of deep transfer learning in AS recognition in eye images. The proposed approach is preferred to previous methods for AS recognition, as it eliminates cumbersome segmentation and feature engineering processes.
PubMed: 32802798
DOI: 10.31661/jbpe.v0i0.2003-1080