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Current Problems in Diagnostic Radiology 2015Asbestos exposure can lead to a variety of adverse effects in the thorax. Although currently in the western world, levels of exposure are kept in check by strict... (Review)
Review
Asbestos exposure can lead to a variety of adverse effects in the thorax. Although currently in the western world, levels of exposure are kept in check by strict regulations, history of previous asbestos exposure continues to have an effect on many, owing to the latent nature of the pathophysiological response of the body to the inhaled fibers. The adverse effects of asbestos generally fall under 3 categories: pleural disease, lung parenchymal disease, and neoplastic disease. Effects on the pleura include pleural effusions, plaques, and diffuse pleural thickening. In the parenchyma, rounded atelectasis, fibrotic bands, and asbestosis are observed. Differentiating asbestosis from other forms of interstitial lung diseases, such as idiopathic pulmonary fibrosis, usual interstitial pneumonia, smoking-related lung disease, and mixed interstitial lung diseases, is important because the prognosis, course of disease, and management of the patient should be tailored based on the specific etiology of the disease. In this review, imaging findings specific to asbestosis are discussed. Finally, exposure to asbestos can lead to neoplastic disease such as pleural mesothelioma, peritoneal mesothelioma, and bronchogenic carcinoma. The purpose of this article is to review the effects of asbestos exposure in the thorax, pathophysiology of these responses, and disease course. Particular emphasis is placed on the radiographic appearance of the disease, discussion of various imaging modalities and their utility, and the role of imaging in the management of patients with previous asbestos exposure and asbestos-related pulmonary disease.
Topics: Asbestosis; Diagnostic Imaging; Disease Progression; Humans; Prognosis
PubMed: 25444537
DOI: 10.1067/j.cpradiol.2014.10.002 -
Annals of the New York Academy of... Dec 1991
Review
Topics: Animals; Asbestos; Asbestosis; Bronchoalveolar Lavage Fluid; Gallium Radioisotopes; Humans; Models, Biological; Radionuclide Imaging; Sheep
PubMed: 1809135
DOI: 10.1111/j.1749-6632.1991.tb24467.x -
RoFo : Fortschritte Auf Dem Gebiete Der... Sep 1984Thirty patients (27 men and 3 women) with an average industrial asbestos exposure of 19 years have been examined. The results of conventional radiography and CT have... (Comparative Study)
Comparative Study
Thirty patients (27 men and 3 women) with an average industrial asbestos exposure of 19 years have been examined. The results of conventional radiography and CT have been analysed and compared with pulmonary function studies. The advantages of CT depend on a better demonstration of the pleura and lung periphery. In 24% of cases plaques were diagnosed by chest x-rays which could, however, be excluded by computed tomography. Correct prediction of restricted ventilation was possible in 84% patients by means of CT. On the other hand, this prediction by means of conventional radiographs could be made reliably only if there was extensive fibrosis.
Topics: Adult; Asbestosis; Construction Materials; Female; Humans; Male; Middle Aged; Textile Industry; Tomography, X-Ray Computed
PubMed: 6435193
DOI: 10.1055/s-2008-1053133 -
Gaceta Sanitaria 2017
Topics: Asbestosis; Humans
PubMed: 28595991
DOI: 10.1016/j.gaceta.2017.02.011 -
Polski Przeglad Radiologii 1987
Review
Topics: Asbestos; Asbestosis; Humans; Lung Diseases; Pleura; Respiratory Function Tests; Sputum; Tomography, X-Ray Computed
PubMed: 3333606
DOI: No ID Found -
Chest Jun 1998
Topics: Asbestosis; Humans; Lung; Pneumoconiosis; Radiography; Respiratory Function Tests
PubMed: 9631773
DOI: 10.1378/chest.113.6.1439 -
Polski Przeglad Radiologii 1987
Review
Topics: Asbestos; Asbestosis; Dust; Humans; Pulmonary Fibrosis
PubMed: 3333605
DOI: No ID Found -
JAMA Jul 1974
Topics: Asbestosis; Environmental Exposure; Humans; Male; Middle Aged; Occupational Diseases; Pleural Effusion; Radiography
PubMed: 4406728
DOI: 10.1001/jama.229.1.23b -
Archives of Internal Medicine Feb 1992The profusion of irregular opacities on chest roentgenograms by International Labour Organisation pneumoconiosis criteria was used to assess the severity of asbestosis... (Comparative Study)
Comparative Study
Severity of pulmonary asbestosis as classified by International Labour Organisation profusion of irregular opacities in 8749 asbestos-exposed American workers. Those who never smoked compared with those who ever smoked.
The profusion of irregular opacities on chest roentgenograms by International Labour Organisation pneumoconiosis criteria was used to assess the severity of asbestosis in 8749 asbestos-exposed active and retired American workers. Seventy-eight percent had no asbestosis (category 0/0 or 0/1), 18.6% had slight asbestosis (1/0 to 1/2), 3% had moderate asbestosis (2/1 to 2/3), and 0.3% had advanced disease (3/2 or greater). Significantly more current smokers had asbestosis than did those who had never smoked, and their average profusion of opacities was higher. The mean age of current smokers with asbestosis was 60 years, whereas subjects with the disease who had never smoked had a mean age of 64 years, a significant difference. Cigarette smoking and asbestosis appear to act synergistically to produce irregular opacities on chest roentgenograms of asbestos-exposed American workers.
Topics: Asbestosis; Humans; Lung; Male; Middle Aged; Occupational Exposure; Radiography; Smoking
PubMed: 1739361
DOI: No ID Found -
Godisen Zbornik Na Medicinskiot... 1974
Topics: Aged; Asbestosis; Female; Humans; Male; Middle Aged; Radiography
PubMed: 4465248
DOI: No ID Found