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Acta Dermatovenerologica Croatica : ADC Jun 2018Bowen's disease, named after John Templeton Bowen, also known as squamous cell carcinoma in situ is a type of non-melanocytic intraepidermal malignancy. It is estimated... (Review)
Review
Bowen's disease, named after John Templeton Bowen, also known as squamous cell carcinoma in situ is a type of non-melanocytic intraepidermal malignancy. It is estimated that in general population around 3% to 5% of Bowen's disease transform into invasive squamous cell cancer. Dermoscopy aims in the identification of the Bowen's disease. The most typical dermoscopic features of Bowen's disease include glomerular vessels and scaly surface. Although dermoscopy of Bowen's disease has been well established other skin lesions may present similar or identical structures in dermoscpic images leading to differential diagnosis dilemmas. Histopathological confirmation should be obtained prior the treatment of suspected cases of Bowen's disease in order to avoid a misdiagnosis.
Topics: Bowen's Disease; Dermoscopy; Humans; Skin Neoplasms
PubMed: 29989873
DOI: No ID Found -
BMJ (Clinical Research Ed.) Mar 2020
Topics: Aged; Bowen's Disease; Cautery; Cryotherapy; Curettage; Disease Management; Female; Fluorouracil; Humans; Practice Guidelines as Topic
PubMed: 32198148
DOI: 10.1136/bmj.m813 -
CA: a Cancer Journal For Clinicians 1990
Review
Topics: Bowen's Disease; Carcinoma, Squamous Cell; Humans; Skin Neoplasms
PubMed: 2114203
DOI: 10.3322/canjclin.40.4.237 -
Diseases of the Colon and Rectum Jun 1988Thirty-three patients with perianal Bowen's disease were treated at the Cleveland Clinic Foundation from 1954 to 1986. Twenty-one patients were women and 12 were men,... (Review)
Review
Thirty-three patients with perianal Bowen's disease were treated at the Cleveland Clinic Foundation from 1954 to 1986. Twenty-one patients were women and 12 were men, ranging in age from 30 to 69 years (mean, 48 years). Twenty patients (61 percent) presented with symptomatic perianal disease, while 13 patients (39 percent) were noted as having perianal Bowen's disease upon pathologic examination of routine hemorrhoidectomy specimens. Ten of the patients (30 percent) had prior histories of unrelated cancer. Twenty-seven patients were managed by wide local excision, three patients by simple excision, three patients by fulguration, and one patient by an abdominoperineal resection. During a follow-up period averaging 3.7 years (range, 0.3 to 10 years), one patient developed a new invasive skin cancer while a second patient experienced a recurrence of perianal Bowen's disease. The characteristic gross appearance of this lesion and its failure to respond to conventional therapy should prompt the performance of a biopsy, which readily establishes the diagnosis. This experience confirms that wide local excision is adequate therapy for perianal Bowen's disease and that close clinical follow-up is necessary to identify disease recurrence or the development of a malignancy.
Topics: Adult; Aged; Anal Canal; Bowen's Disease; Carcinoma, Squamous Cell; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Perineum; Skin Neoplasms
PubMed: 3288448
DOI: 10.1007/BF02552608 -
British Journal of Hospital Medicine... Jul 2022
Topics: Bowen's Disease; Carcinoma, Squamous Cell; Hand; Humans; Skin Neoplasms
PubMed: 35938755
DOI: 10.12968/hmed.2021.0613 -
Wiener Medizinische Wochenschrift (1946) Oct 2015Bowen's disease of the nail apparatus is uncommon. Since often characteristic clinical features are missing, diagnosis and treatment are delayed. We have analyzed our... (Review)
Review
Bowen's disease of the nail apparatus is uncommon. Since often characteristic clinical features are missing, diagnosis and treatment are delayed. We have analyzed our patients' files from January 2001 to July 2015 for this disorder. We identified eight patients with Bowen's disease of the nail apparatus, six male and two female individuals. Fingers were more often affected than toes. The disease does not respect the anatomical borders of the nail apparatus. Therefore, we performed delayed Mohs surgery with skin grafts in seven patients and with second intention healing in one patient. Two relapses were noted but only one ate the same digit. Since relapses occurred after 2-3 years, a follow-up of such patients seems justified.
Topics: Adult; Aged; Aged, 80 and over; Bowen's Disease; Combined Modality Therapy; Female; Humans; Male; Middle Aged; Mohs Surgery; Nail Diseases; Skin Neoplasms; Skin Transplantation
PubMed: 26376982
DOI: 10.1007/s10354-015-0383-4 -
Giornale Italiano Di Dermatologia E... Oct 2016
Topics: Bowen's Disease; Female; Fingers; Humans; Middle Aged; Skin Neoplasms
PubMed: 27595211
DOI: No ID Found -
The Breast Journal Jun 2020Bowen's disease or squamous cell carcinoma in situ is a precursor malignant neoplasm restricted to the epidermis. Clinically and histologically, Bowen's disease of the... (Review)
Review
INTRODUCTION
Bowen's disease or squamous cell carcinoma in situ is a precursor malignant neoplasm restricted to the epidermis. Clinically and histologically, Bowen's disease of the nipple can resemble Paget's disease. It is crucial to differentiate between the two with immunohistological staining in order to provide the appropriate treatment. This review of Bowen's disease of the nipple will examine the diagnostic and treatment modalities previously used. We also present our own case of Bowen's disease of the nipple and propose a clinical pathway for this rare disease process.
METHODS
A review of published literature using MEDLINE, PubMed, and Google Scholar revealed seven articles were identified with a total of eight cases of Bowen's disease of the nipple.
RESULTS
Treatment modalities varied within the literature. This ranged from photodynamic therapy to simple mastectomy and sentinel lymph node biopsy. Standard surgical margins are inadequate for Bowen's disease of the nipple, as it has been shown to spread along the lactiferous ducts. Our case is of a 57-year-old female with Bowen's disease of her right nipple, confirmed through immunohistological staining. Wide local excision with immediate full-thickness skin graft reconstruction was performed and is now disease-free with a healed graft.
CONCLUSION
There is no accepted management pathway for Bowen's disease of the nipple. We propose a treatment algorithm that involves immunohistological staining to diagnose Bowen's disease of the nipple. This would then be followed by a wide local excision, complete nipple excision including underlying lactiferous ducts and glandular tissue and subsequent reconstruction.
Topics: Bowen's Disease; Breast Neoplasms; Female; Humans; Mastectomy; Middle Aged; Nipples; Skin Neoplasms
PubMed: 32212188
DOI: 10.1111/tbj.13824 -
Journal of the American Podiatric... Mar 1986
Topics: Bowen's Disease; Carcinoma, Squamous Cell; Foot Diseases; Humans; Male; Skin Neoplasms
PubMed: 3958940
DOI: 10.7547/87507315-76-3-153 -
CA: a Cancer Journal For Clinicians 1977
Topics: Arsenic Poisoning; Bowen's Disease; Carcinoma, Squamous Cell; Female; Humans; Male; Middle Aged; Neoplasms, Multiple Primary; Skin Neoplasms
PubMed: 406015
DOI: 10.3322/canjclin.27.3.160