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Alimentary Pharmacology & Therapeutics Apr 2023
PubMed: 36952266
DOI: 10.1111/apt.17444 -
Arthroscopy : the Journal of... Feb 2019Regardless of the technique utilized, tunnel expansion following anterior cruciate ligament reconstruction remains a mystery and a clinical challenge. No procedure seems...
Regardless of the technique utilized, tunnel expansion following anterior cruciate ligament reconstruction remains a mystery and a clinical challenge. No procedure seems to be immune to this, even anatomic double-bundle reconstruction. This technique was introduced more than 20 years ago and showed great promise while also contributing significantly to our current knowledge of anterior cruciate ligament anatomy and biomechanics. However, we must remember that new techniques do carry with them new side effects that we must document and acknowledge if we hope to improve our surgical outcomes.
Topics: Absorbable Implants; Anterior Cruciate Ligament Injuries; Anterior Cruciate Ligament Reconstruction; Biomechanical Phenomena; Bone Screws; Deja Vu; Follow-Up Studies; Humans; Knee Joint; Prospective Studies
PubMed: 30712630
DOI: 10.1016/j.arthro.2018.10.112 -
British Dental Journal Aug 2009
Topics: Environment; Humans; Malocclusion; Mandible; Maxillofacial Development
PubMed: 19662038
DOI: 10.1038/sj.bdj.2009.677 -
Cardiovascular Research Mar 2011This brief review looks back to the major theoretical, experimental, and clinical work on the dynamics and mechanisms of atrial fibrillation (AF). Its goal is to... (Review)
Review
This brief review looks back to the major theoretical, experimental, and clinical work on the dynamics and mechanisms of atrial fibrillation (AF). Its goal is to highlight the most important issues, controversies, and advances that have driven the field of investigation into AF mechanisms at any given time during the last ∼100 years. It emphasizes that while the history of AF research has been full of controversies from the start, such controversies have led to new information, and individual scientists have learned from those that have preceded them. However, in the face of the most common sustained cardiac arrhythmia seen in clinical practice, we are yet to fully understand its fundamental mechanisms and learn how to treat it effectively. Future research into AF dynamics and mechanisms should focus on the development and validation of new numerical and animal models. Such models should be relevant to and accurately reproduce the important substrates associated with ageing and with diseases such as hypertension, heart failure, and ischaemic heart disease which cause AF in the vast majority of patients. Knowledge derived from such models may help to greatly advance the field and hopefully lead to more effective prevention and therapy.
Topics: Animals; Atrial Fibrillation; Deja Vu; History, 20th Century; Humans
PubMed: 21097807
DOI: 10.1093/cvr/cvq364 -
Memory (Hove, England) Jan 2017
Topics: Deja Vu; Dissociative Disorders; Humans; Memory
PubMed: 27905254
DOI: 10.1080/09658211.2017.1244881 -
The British Journal of General Practice... 2021
Topics: Health Status Disparities; Humans
PubMed: 33632678
DOI: 10.3399/bjgp21X714941 -
The Behavioral and Brain Sciences Nov 2023Rather than a natural product, a computational analysis leads us to characterize déjà vu as a failure of memory retrieval, linked to the activation in neocortex of...
Rather than a natural product, a computational analysis leads us to characterize déjà vu as a failure of memory retrieval, linked to the activation in neocortex of familiar items from a compositional memory in the absence of hippocampal input, and to a misappropriation by the self of what is of others.
Topics: Humans; Memory; Hippocampus
PubMed: 37961795
DOI: 10.1017/S0140525X2300016X -
Psychological Science Apr 2018Déjà vu is beginning to be scientifically understood as a memory phenomenon. Despite recent scientific advances, a remaining puzzle is the purported association...
Déjà vu is beginning to be scientifically understood as a memory phenomenon. Despite recent scientific advances, a remaining puzzle is the purported association between déjà vu and feelings of premonition. Building on research showing that déjà vu can be driven by an unrecalled memory of a past experience that relates to the current situation, we sought evidence of memory-based predictive ability during déjà vu states. Déjà vu did not lead to above-chance ability to predict the next turn in a navigational path resembling a previously experienced but unrecalled path (although such resemblance increased reports of déjà vu). However, déjà vu states were accompanied by increased feelings of knowing the direction of the next turn. The results suggest that feelings of premonition during déjà vu occur and can be illusory. Metacognitive bias brought on by the state itself may explain the peculiar association between déjà vu and the feeling of premonition.
Topics: Computer Simulation; Deja Vu; Humans; Illusions; Recognition, Psychology
PubMed: 29494276
DOI: 10.1177/0956797617743018 -
Annals of the Royal College of Surgeons... Mar 2008
Topics: Humans; Laparoscopy; Surgical Instruments; Sutures; Umbilicus
PubMed: 18325229
DOI: 10.1308/003588408X261807 -
Memory (Hove, England) Aug 2021Past research has demonstrated a relationship between déjà vu and the entorhinal cortex in patients with wider medial temporal lobe damage. The aim of the present...
Past research has demonstrated a relationship between déjà vu and the entorhinal cortex in patients with wider medial temporal lobe damage. The aim of the present research was to investigate this crucial link in a patient (MR) with a selective lesion to the left lateral entorhinal cortex to provide a more direct exploration of this relationship. Two experiments investigated the experiences of déjà vécu (using the IDEA questionnaire) and déjà vu (using an adapted DRM paradigm) in MR and a set of matched controls. The results demonstrated that MR had quantitatively more and qualitatively richer recollective experiences of déjà vécu. In addition, under laboratory-based déjà vu conditions designed to elicit both false recollection (critical lures) and false familiarity (weakly-associated lures), MR only revealed greater memory impairments for the latter. The present results are therefore the first to demonstrate a direct relationship between the entorhinal cortex and the experience of both déjà vu and déjà vécu. They furthermore suggest that the entorhinal cortex is involved in both weakly-associative false memory as well as strongly-associative memory under conditions that promote familiarity-based processing.
Topics: Entorhinal Cortex; Humans; Memory Disorders; Mental Recall; Recognition, Psychology; Temporal Lobe
PubMed: 30403917
DOI: 10.1080/09658211.2018.1543436