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Contact Dermatitis Nov 2019
Topics: Adult; Female; Humans; Hypersensitivity, Delayed; Irritants; Latex Hypersensitivity; Nickel; Thiram
PubMed: 31290999
DOI: 10.1111/cod.13353 -
British Medical Bulletin Jan 1967
Review
Topics: Autoimmune Diseases; Humans; Hypersensitivity, Delayed; In Vitro Techniques
PubMed: 5342383
DOI: 10.1093/oxfordjournals.bmb.a070519 -
Journal of Investigational Allergology... Jun 2018
Topics: Administration, Oral; Dimethyl Fumarate; Female; Humans; Hypersensitivity, Delayed; Middle Aged
PubMed: 29939143
DOI: 10.18176/jiaci.0239 -
Journal of Psychiatric Practice Mar 2022Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a rare but severe cutaneous drug hypersensitivity reaction. Delays in making a diagnosis of DRESS...
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a rare but severe cutaneous drug hypersensitivity reaction. Delays in making a diagnosis of DRESS syndrome and lack of timely treatment may result in morbidity and mortality. However, the presentation can be misinterpreted as other pathologies because of a broad spectrum of clinical presentations, delayed reactions, and prolonged course. Despite the discontinuation of the medication that is the culprit, relapses of drug reactions frequently occur weeks to months later. Several drugs that are associated with DRESS syndrome are prescribed as psychotropic medications. This report describes the case of a patient with DRESS syndrome who was evaluated with the RegiSCAR scoring system as a "definite case," which was possibly induced by carbamazepine prescribed to treat bipolar I disorder. The young female patient was successfully treated with steroid medication after carbamazepine was discontinued. She was prescribed aripiprazole for mood stabilization without a subsequent recurrence of DRESS syndrome. We recommend that, in cases such as described here, clinicians take DRESS syndrome into consideration and provide proper timely management, particularly for patients receiving psychotropic drugs. A brief review of the literature concerning DRESS syndrome associated with psychotropic drugs and its pathogenesis are outlined and discussed.
Topics: Aripiprazole; Benzodiazepines; Carbamazepine; Drug Hypersensitivity Syndrome; Female; Humans; Hypersensitivity, Delayed
PubMed: 35238828
DOI: 10.1097/PRA.0000000000000619 -
Triangle; the Sandoz Journal of Medical... 1966
Review
Topics: Animals; Guinea Pigs; History, 18th Century; History, 19th Century; History, 20th Century; Humans; Hypersensitivity, Delayed
PubMed: 5339211
DOI: No ID Found -
Advances in Experimental Medicine and... 2017Polymorphous light eruption (PLE) is the commonest immuno-mediated photodermatosis. It occurs after solar or artificial UV-light exposure and affects only the... (Review)
Review
Polymorphous light eruption (PLE) is the commonest immuno-mediated photodermatosis. It occurs after solar or artificial UV-light exposure and affects only the sun-exposed areas with preference of the V-area of the chest, of arms and forearms, legs, upper part of the back, and rarely the face. The lesions are itching or burning, and vary morphologically from erythema to papules, vesico-papules and occasionally blisters, plaques, sometimes erythema multiforme-like, insect bite-like wheals and purpura. The clinical manifestations befall within a few hours to days from light exposure, last a few days, and subside in about a week without sequelae. Its diagnosis is based on history, morphology and phototests. PLE is considered as a delayed hypersensitivity response to newly UV induced, but still unidentified, antigen(s). Usually, MED is normal, but the provocative phototests with UVA or UVB reproduce the spontaneous lesions in about 50% of the patients. Broad spectrum sunscreens and antioxidants, photohardening with PUVA or narrow band UVB may be beneficial to prevent the disease. Therapy is based mainly on topical or systemic corticosteroids.
Topics: Adrenal Cortex Hormones; Animals; Antioxidants; Humans; Hypersensitivity, Delayed; PUVA Therapy; Photosensitivity Disorders; Risk Factors; Skin; Sunlight; Sunscreening Agents; Treatment Outcome; Ultraviolet Rays
PubMed: 29124691
DOI: 10.1007/978-3-319-56017-5_6 -
Annals of Internal Medicine May 2004
Topics: Drug Administration Schedule; Drug Hypersensitivity; Humans; Hypersensitivity, Delayed
PubMed: 15126275
DOI: 10.7326/0003-4819-140-9-200405040-00028-w1 -
Journal of Investigational Allergology... Aug 2019
Topics: Aged; Drug Hypersensitivity; Humans; Hypersensitivity, Delayed; Immunologic Factors; Lenalidomide; Male; Phenotype; Skin Tests
PubMed: 31478529
DOI: 10.18176/jiaci.0386 -
Clinical Reviews in Allergy & Immunology 1995
Review
Topics: Allergens; Animals; Antigens, Dermatophagoides; Dermatitis, Atopic; Glycoproteins; Humans; Hypersensitivity, Delayed; Mites; Skin Tests
PubMed: 7489262
DOI: 10.1007/BF02758100 -
Allergy Feb 1996
Topics: Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed; Intradermal Tests; Middle Aged; Penicillins
PubMed: 8738523
DOI: 10.1111/j.1398-9995.1996.tb04573.x