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Contact Dermatitis Oct 1992
Topics: Cefuroxime; Drug Eruptions; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delayed; Middle Aged
PubMed: 1451507
DOI: 10.1111/j.1600-0536.1992.tb03271.x -
Clinical Pediatrics Sep 1973
Review
Topics: B-Lymphocytes; Cell Migration Inhibition; Humans; Hypersensitivity, Delayed; Immunity, Cellular; Lymphocyte Activation; Macrophages; T-Lymphocytes; Viral Plaque Assay
PubMed: 4579892
DOI: No ID Found -
British Medical Bulletin Jan 1967
Review
Topics: Animals; Antibody Formation; Hypersensitivity, Delayed; Macrophages
PubMed: 5342380
DOI: 10.1093/oxfordjournals.bmb.a070516 -
Immunology and Allergy Clinics of North... Aug 2014In the last several years, intravenous therapy with iron products has been more widely used. Although it has been a standard procedure in dialysis-associated anemia... (Review)
Review
In the last several years, intravenous therapy with iron products has been more widely used. Although it has been a standard procedure in dialysis-associated anemia since the early 1990s, its use is expanding to a host of conditions associated with iron deficiency, especially young women with heavy uterine bleeding and pregnancy. Free iron is associated with unacceptable high toxicity inducing severe, hemodynamically significant symptoms. Subsequently, formulations that contain the iron as an iron carbohydrate nanoparticle have been designed. With newer formulations, including low-molecular-weight iron dextran, iron sucrose, ferric gluconate, ferumoxytol, iron isomaltoside, and ferric carboxymaltose, serious adverse events are rare.
Topics: Administration, Intravenous; Drug Hypersensitivity; Ferric Compounds; Ferrous Compounds; Humans; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Iron; Risk Factors
PubMed: 25017687
DOI: 10.1016/j.iac.2014.04.013 -
Allergologia Et Immunopathologia 2011
Topics: Administration, Oral; Aged; Anticoagulants; Cross Reactions; Eczema; Enoxaparin; Female; Fondaparinux; Heparin, Low-Molecular-Weight; Humans; Hypersensitivity, Delayed; Immunization; Injections, Subcutaneous; Orthopedic Procedures; Polysaccharides; Postoperative Complications; Pruritus; Skin Tests; Thrombosis
PubMed: 21129837
DOI: 10.1016/j.aller.2010.08.002 -
Journal of Investigational Allergology... Feb 2019
Topics: Adult; Antineoplastic Agents, Alkylating; Bendamustine Hydrochloride; Desensitization, Immunologic; Drug Hypersensitivity; Humans; Hypersensitivity, Delayed; Male; Skin Tests
PubMed: 30785109
DOI: 10.18176/jiaci.0335 -
Contact Dermatitis Oct 2022
Topics: Dermatitis, Allergic Contact; Exanthema; Humans; Hypersensitivity, Delayed; Patch Tests; Triiodobenzoic Acids
PubMed: 35687812
DOI: 10.1111/cod.14171 -
British Medical Bulletin Jan 1967
Review
Topics: Desensitization, Immunologic; Haptens; Hypersensitivity, Delayed; Species Specificity
PubMed: 5342373
DOI: 10.1093/oxfordjournals.bmb.a070509 -
Contact Dermatitis Sep 2021
Topics: Adult; Clavulanic Acid; Female; Humans; Hypersensitivity, Delayed; Male; Middle Aged; Patch Tests; beta-Lactamase Inhibitors
PubMed: 33837970
DOI: 10.1111/cod.13859 -
Aesthetic Surgery Journal Apr 2020Hyaluronic acid (HA) dermal filler injection is believed to be a safe procedure. However, with the increase in the number of performed procedures and indications, the...
A Systematic Review of the Literature of Delayed Inflammatory Reactions After Hyaluronic Acid Filler Injection to Estimate the Incidence of Delayed Type Hypersensitivity Reaction.
BACKGROUND
Hyaluronic acid (HA) dermal filler injection is believed to be a safe procedure. However, with the increase in the number of performed procedures and indications, the number of product-related complications, especially delayed inflammatory reactions, has also increased. Delayed-type hypersensitivity (DTH) reaction is one of these delayed inflammatory reactions, which is preventable by performing a pretreatment skin test.
OBJECTIVES
The authors sought to find the incidence of delayed inflammatory reactions and DTH reaction after HA injection and to determine whether a pretreatment skin test is worthwhile to be performed.
METHODS
The authors conducted a systematic literature review of all the relevant prospective studies, retrospective studies, and case reports on delayed inflammatory reactions and DTH reaction after HA filler injection.
RESULTS
The incidence of delayed inflammatory reactions calculated from the prospective studies was 1.1% per year, and that of possible DTH reaction was 0.06% per year. Most retrospective studies estimated a percentage of delayed inflammatory reactions of less than 1% in 1 to 5.5 years. The incidence of DTH reaction would be lower than that. Among all the DTH cases reported, only about 5% of them were proven to be genuine DTH reactions.
CONCLUSIONS
The incidence of both delayed inflammatory reactions and DTH reaction is low. There is evidence that genuine DTH reactions caused by HA fillers approved by the Food and Drug Administration do exist. This adverse event can be prevented by performing a pretreatment skin test. However, the incidence of DTH reaction is so low that the pretreatment skin test is not mandatory if Food and Drug Administration-approved HA fillers are used.
Topics: Humans; Hyaluronic Acid; Hypersensitivity, Delayed; Incidence; Prospective Studies; Retrospective Studies
PubMed: 31410442
DOI: 10.1093/asj/sjz222