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Journal of the American Academy of... Dec 2023In 2020, Beck et al described a novel adult autoinflammatory syndrome entitled VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic), a newly-discovered... (Review)
Review
In 2020, Beck et al described a novel adult autoinflammatory syndrome entitled VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic), a newly-discovered disorder that connected previously unrelated inflammatory syndromes and a prototype for a new class of hematoinflammatory diseases. Eighty-nine percent of published cases have documented skin involvement, but despite the high incidence and diagnostic accessibility of skin manifestations, there has been little focus on the dermatological features of VEXAS syndrome thus far. A PubMed search of all published case reports of VEXAS syndrome to date was performed, with inclusion of all cases confirmed by genetic sequencing, and this review summarizes the reported dermatological signs. There have already been 141 confirmed published cases since original publication, 126 of which had documented cutaneous signs. A wide range of skin presentations are reported, including Sweet-like urticated and tender erythematous nodules, cartilaginous involvement with chondritis, cutaneous vasculitis, and periorbital angiodema. Many patients had been diagnosed with Sweet syndrome, relapsing polychondritis, polyarteritis nodosa, or erythema nodosum. Hallmarks of skin histopathology are a neutrophilic dermatosis with coexisting or exclusive leukocytoclastic vasculitis. The new classification therefore helps link previously disparate inflammatory skin conditions into a unifying pathophysiological pathway.
Topics: Adult; Humans; Vacuoles; Dermatologists; Skin; Dermatitis; Mutation
PubMed: 35121074
DOI: 10.1016/j.jaad.2022.01.042 -
Clinics in Dermatology 2023Dermatology is a specialty reliant on presenting detailed and accurate visual observations. Digital photography is a highly prevalent and accessible technology that can... (Review)
Review
Dermatology is a specialty reliant on presenting detailed and accurate visual observations. Digital photography is a highly prevalent and accessible technology that can be easily incorporated into a dermatology practice to facilitate documentation and communication of clinical findings. Dermatologists will benefit from being comfortable with digital photography and techniques to improve their photography skills. This review presents the fundamentals of photography and techniques helpful in capturing an adequate image. We explore the application of photography in the setting of microscopy, dermatopathology, dermatoscopy, and Wood's lamp. Lastly, new imaging technologies, such as multispectral and infrared imaging, are discussed.
Topics: Humans; Skin Diseases; Dermatology; Dermatologists; Photography; Medicine
PubMed: 36252727
DOI: 10.1016/j.clindermatol.2022.10.001 -
Dermatologic Clinics Oct 2023The practice of medicine is governed by legislation and regulation at the state and national level. It is crucial, therefore, that dermatologists become and remain... (Review)
Review
The practice of medicine is governed by legislation and regulation at the state and national level. It is crucial, therefore, that dermatologists become and remain involved in the process to advocate for their patients, their practices, and the specialty itself. Maintaining a relationship with one's state and federal senators and representatives is critical for physicians to have a voice in the shaping of health care policy. Local, state, and national medical and specialty societies are a tremendous resource for physicians to remain abreast of policies affecting the practice of medicine.
Topics: Humans; Political Activism; Dermatologists; Health Policy
PubMed: 37718023
DOI: 10.1016/j.det.2023.05.004 -
International Journal of Pharmaceutical... 2023Topical treatment is mainstay for a variety of dermatologic conditions. There are several different types of topical vehicles, and choosing the most appropriate one... (Review)
Review
Topical treatment is mainstay for a variety of dermatologic conditions. There are several different types of topical vehicles, and choosing the most appropriate one is an essential part of treatment. Selection can vary depending on factors such as patient preference and anatomical location. Each topical vehicle has unique advantages and disadvantages that are important to consider. This article reviews some of the most common topical vehicles used in dermatology.
Topics: Humans; Dermatologists; Administration, Topical
PubMed: 37595171
DOI: No ID Found -
Revue Medicale Suisse Apr 2020Recent progress in molecular engineering, digital imaging and artificial intelligence improve human modern medicine to levels never seen before. Digital pathology... (Review)
Review
Recent progress in molecular engineering, digital imaging and artificial intelligence improve human modern medicine to levels never seen before. Digital pathology becomes the new standard of patient care in dermatology and personalized medicine. It is increasingly used for digital exchange of histological slides, personalized consultations, tumor boards, quantitative image analysis for research purposes and in education. Digital pathology allows automatization and quantification with greater consistency and accuracy than light microscopy. Personalized dermatology is focusing on tailoring therapy to the individual characteristics of each patient and allow to use genetic information in order to develop a treatment plan, uniquely suited to each patient, which in turn leads to improved quality of care and management of each individual.
Topics: Artificial Intelligence; Computers; Dermatologists; Dermatology; Humans; Pathology
PubMed: 32239834
DOI: No ID Found -
The Journal of Dermatology Jul 2021As cancer treatment advances, the need for dermatologists in the treatment process is increasing. Cancer patients often experience cutaneous manifestations of internal... (Review)
Review
As cancer treatment advances, the need for dermatologists in the treatment process is increasing. Cancer patients often experience cutaneous manifestations of internal diseases and dermatological adverse events from chemotherapy, radiation, surgery, and stem cell transplants. These diminish patients' health-related quality of life and negatively affect cancer treatment adherence. To identify the dermatologist's role, we analyzed 893 cases of in-hospital dermatology consultations at the Niigata Cancer Center Hospital during 2019. The number of dermatology consultations was the second highest among all hospital departments. Malignant tumors accounted for 91.7% of the underlying diseases, including hematological, gastrointestinal, and lung cancer as the top three primary cancers. The most common consultation category was inflammatory skin disorders (29.2%), followed by chemotherapy-related skin disorders (23.5%), cutaneous infections (11.5%), skin tumors (9.5%), and continued treatment of pre-existing skin disorders (8.8%). The average intervention time was the longest for continued treatment of existing skin disorders (229 ± 60.6 days), followed by malignant wound management (126 ± 60.6 days) and chemotherapy-related skin disorders (122 ± 60.6 days). The median overall survival time of the 27 patients in the malignant wound management group was 5 months (95% confidence interval, 1.8-8.2 months) from the initial dermatology consultation. Our results show an increasing demand for dermatologists in cancer management. However, the number of full-time dermatologists is insufficient in some Japanese cancer hospitals. There is a need to consider increasing the number of adequately trained dermatologists in cancer medical settings.
Topics: Cancer Care Facilities; Dermatologists; Dermatology; Humans; Neoplasms; Quality of Life; Referral and Consultation; Skin Diseases
PubMed: 33829529
DOI: 10.1111/1346-8138.15876 -
Indian Journal of Dermatology,...
Topics: Humans; Dermatology; Dermatologists; Social Media
PubMed: 38595020
DOI: 10.25259/IJDVL_178_2024 -
Journal of Cosmetic Dermatology Jan 2023Cosmetic gynecology is an expanding field with a steep rise in awareness and demand for procedures to enhance the aesthetic appearance of female genitalia. (Review)
Review
INTRODUCTION
Cosmetic gynecology is an expanding field with a steep rise in awareness and demand for procedures to enhance the aesthetic appearance of female genitalia.
AIM
This article aims to provide an overview of aesthetic gynecology for a practicing dermatologist.
METHODS
A study conducted in India showed a rising trend in the demand of aesthetic vaginal procedures from 3.9% in 2012 to 28.97% in 2015.
CONCLUSION
Several aesthetic modalities such as peels, platelet rich plasma, and energy-based devices and surgical modalities have been in use, though serious evidence for efficacy of many of these procedures is lacking.
Topics: Female; Humans; Gynecology; Dermatologists; Rejuvenation; Vagina; Cosmetics; Cosmetic Techniques
PubMed: 36335587
DOI: 10.1111/jocd.15484 -
Primary Care Mar 2022
Topics: Dermatologists; Humans
PubMed: 35125162
DOI: 10.1016/j.pop.2021.12.003 -
Clinical and Experimental Dermatology Oct 2023Facial hair is a commonly desired feature for many individuals. Despite a breadth of dermatology literature covering strategies for removing facial hair, there are no... (Review)
Review
Facial hair is a commonly desired feature for many individuals. Despite a breadth of dermatology literature covering strategies for removing facial hair, there are no known articles summarizing strategies for facial hair growth or reviewing common facial hair pathologies. Here, we assess Google Trends to describe significant increases in search terms related to facial hair growth and maintenance over the last decade, suggesting an increased public interest in this topic. Next, we review ethnic differences that may affect facial hair distribution, growth, and predisposition to certain facial hair pathologies. Lastly, we review studies on agents used for facial hair growth and review common facial hair pathologies.
Topics: Humans; Dermatologists; Hair; Face; Hair Removal; Scalp
PubMed: 37310915
DOI: 10.1093/ced/llad201