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Journal de Mycologie Medicale Mar 2015Dermatomycosis is characterized by both superficial and subcutaneous infections of keratinous tissues and mucous membranes caused by a variety of fungal agents, the two... (Review)
Review
Dermatomycosis is characterized by both superficial and subcutaneous infections of keratinous tissues and mucous membranes caused by a variety of fungal agents, the two most common classes being dermatophytes and yeasts. Overall, the stepwise process of host infection is similar among the main dermatomycotic species; however, the species-specific ability to elicit a host reaction upon infection is distinct. Yeasts such as Candida albicans elicit a relatively low level of host tissue damage and inflammation during pathogenic infection, while dermatophytes may induce a higher level of tissue damage and inflammatory reaction. Both pathogens can, however, manipulate the host's immune response, ensuring survival and prolonging chronic infection. One common element of most dermatomycotic infections is the disease burden caused by inflammation and associated signs and symptoms, such as erythema, burning and pruritus. There is a strong clinical rationale for the addition of a topical corticosteroid agent to an effective antimycotic therapy, especially in patients who present with inflammatory dermatomycoses (e.g., tinea inguinalis). In this review, we aim to compare the pathogenesis of common dermatomycotic species, including Candida yeasts (Candida albicans), dermatophytes (Trichophyton, Epidermophyton or Microsporum species), and other pathogenic yeasts (Malassezia), with a special focus on unique species-specific aspects of the respective infection processes, the interaction between essential aspects of pathogenic infection, the different roles of the host inflammatory response, and the clinical consequences of the infection-related tissue damage and inflammation. We hope that a broader understanding of the various mechanisms of dermatomycoses may contribute to more effective management of affected patients.
Topics: Adaptation, Physiological; Antifungal Agents; Arthrodermataceae; Dermatitis; Dermatomycoses; Host-Pathogen Interactions; Humans; Inflammation; Skin
PubMed: 25662199
DOI: 10.1016/j.mycmed.2014.11.002 -
JAMA Aug 1960
Topics: Dermatomycoses; Griseofulvin
PubMed: 13793599
DOI: 10.1001/jama.1960.03020320022006 -
Mycopathologia Et Mycologia Applicata Dec 1962
Review
Topics: Actinomycosis; Arthrodermataceae; Aspergillosis; Blastomycosis; Brazil; Candidiasis; Chromoblastomycosis; Cryptococcosis; Dermatomycoses; Histoplasmosis; Humans; Lung Diseases; Lung Diseases, Fungal; Mucormycosis; Mycetoma; Mycology; Mycoses; Nocardia Infections; Rhinosporidiosis; Sporotrichosis
PubMed: 14059712
DOI: 10.1007/BF02051452 -
Current Therapeutic Research, Clinical... Jan 1974
Clinical Trial
Topics: Adolescent; Adult; Aged; Antifungal Agents; Candida; Candida albicans; Child; Clinical Trials as Topic; Dermatomycoses; Epidermophyton; Female; Humans; Imidazoles; Male; Middle Aged; Time Factors; Trichophyton; Trityl Compounds
PubMed: 4203845
DOI: No ID Found -
Revista Medica de Chile Apr 1974
Comparative Study
Topics: Adult; Child; Chile; Dermatomycoses; Female; Fungi; Hair; Humans; Male; Nails; Skin
PubMed: 4157407
DOI: No ID Found -
Iryo Feb 1970
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Dermatomycoses; Female; Humans; Humidity; Infant; Japan; Male; Middle Aged; Sex Factors; Temperature
PubMed: 5443808
DOI: No ID Found -
Zeitschrift Fur Haut- Und... Jul 1954
Topics: Dermatomycoses; Nail Diseases; Nails; Skin Diseases; Tinea
PubMed: 14374817
DOI: No ID Found -
Revista Da Sociedade Brasileira de... 2009This study had the aim of isolating and identifying keratinophilic fungi from soil and correlating them with dermatomycosis agents. According to our results, the...
This study had the aim of isolating and identifying keratinophilic fungi from soil and correlating them with dermatomycosis agents. According to our results, the predominance of Trichophyton tonsurans as a dermatomycosis agent among children in the city of Recife, PE, is probably due to children's greater contact with soil.
Topics: Brazil; Child; Dermatomycoses; Humans; Mitosporic Fungi; Prevalence; Public Facilities; Soil Microbiology
PubMed: 19802490
DOI: 10.1590/s0037-86822009000400023 -
Journal of Wildlife Diseases Jan 1974
Topics: Alberta; Animals; Deer; Dermatomycoses; Female
PubMed: 4810221
DOI: 10.7589/0090-3558-10.1.74 -
Medical Mycology Journal 2013
Topics: Candidiasis, Cutaneous; Dermatomycoses; Humans; Imidazoles; Ointments
PubMed: 23760070
DOI: 10.3314/mmj.54.101