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Pediatrics in Review Jan 2021
Topics: Diagnosis, Differential; Diaper Rash; Humans; Infant
PubMed: 33386307
DOI: 10.1542/pir.2020-0128 -
Pediatric Dermatology Mar 2018Diaper dermatitis (DD) is one of the most common skin conditions that infants suffer from and their caregivers manage in the first months post-birth. As such, questions...
Diaper dermatitis (DD) is one of the most common skin conditions that infants suffer from and their caregivers manage in the first months post-birth. As such, questions of effective prevention and treatment of the condition often arise. Nonmedical skincare practices that support healthy skin barrier function can prevent DD manifestation or alleviate the condition in many cases. The usage of barrier emollients and improved diaper technology contributes to keeping moisture and irritants away from an infant's delicate skin. This paper addresses facts behind commonly asked questions from caregivers regarding DD and discusses effective measures to prevent and treat the condition.
Topics: Caregivers; Diaper Rash; Diapers, Infant; Emollients; Humans; Infant; Infant Care; Infant, Newborn; Skin Care
PubMed: 29596731
DOI: 10.1111/pde.13495 -
Pediatric Nursing 2004
Review
Topics: Diaper Rash; Humans; Infant; Infant Care; Nurse's Role; Nursing Assessment; Ointments; Pediatric Nursing; Petrolatum; Primary Prevention; Skin Care; Zinc Oxide
PubMed: 15704594
DOI: No ID Found -
Journal of Cosmetic Dermatology Apr 2021Diaper dermatitis (DD) is an acute inflammatory reaction, regardless of the cause, of the diaper-covered area. Topical skin barrier repair cosmetic products are the... (Clinical Trial)
Clinical Trial
BACKGROUND
Diaper dermatitis (DD) is an acute inflammatory reaction, regardless of the cause, of the diaper-covered area. Topical skin barrier repair cosmetic products are the mainstay treatment to cure and/or prevent DD.
AIMS
To assess the efficacy/tolerability of a zinc gluconate-taurine/zinc oxide and panthenol/ glycerin/ Butyrospermum parkii butter barrier cream using clinical evaluation.
METHODS
In this prospective, open-label trial, 20 patients (10 infants/10 adults), with mild/moderate DD enrolled at the Dermatology University Clinic of Catania (Italy) were instructed to apply the cream twice daily for 30 days. Degree of erythema was performed clinically by a 5-point severity scale (from 0 = no erythema to 4 = severe erythema), at baseline, at 15 and 30 days. An Investigator Global Assessment (IGA) using a 6-point scale (from -1 = worsening to 4 = complete response/clear) along with product tolerability was also performed at 15 and 30 days. Statistical analysis was performed using SAS version 9.
RESULTS
At 15 days, a reduction of clinical erythema assessment (CEA) from baseline was observed (mean from 3.2 ± 0.8 to 2.5 ± 0.3; p < 0.06), that although nonsignificant, showed a significant progressive improvement at 30 days (mean from 3.2 ± 0.8 to 1.1 ± 0.9; p < 0.0001) without any age differences.
CONCLUSIONS
Our preliminary results indicate that the tested barrier cream may represent a promising approach in DD rash. It may be used in mild-to-moderate forms in monotherapy without significant side effects or, where required, in association with pharmacological agents. Its long-term use is likely safe.
Topics: Adult; Diaper Rash; Emollients; Humans; Infant; Prospective Studies; Skin; Treatment Outcome; Zinc Oxide
PubMed: 33934478
DOI: 10.1111/jocd.14091 -
The Journal of Pediatrics Mar 2019
Topics: Biotinidase Deficiency; Diaper Rash; Female; Humans; Infant; Seizures
PubMed: 30392870
DOI: 10.1016/j.jpeds.2018.09.042 -
Pediatric Dermatology Jan 2019Understanding the importance of the barrier function of the skin of preterm and term neonates is crucial in effective neonatal skin and diaper care. This literature... (Review)
Review
BACKGROUND
Understanding the importance of the barrier function of the skin of preterm and term neonates is crucial in effective neonatal skin and diaper care. This literature search aimed to review the development of different practices in neonatal care to maintain skin barrier function, in turn preventing diaper dermatitis.
METHODS
We performed two quantitative literature searches of English language studies: an initial literature search of studies published in the last 5 years was conducted using Cinahl, Medline, Embase, British Nursing Index, and DelphiS, followed by a second search of publications from 1990 to 2017 using the National Institute of Clinical Excellence Health Databases Advanced Search using key words, synonyms, and Boolean phrasing. Titles and abstracts were reviewed for relevance.
RESULTS
One hundred ten studies were analyzed for the purpose of this review; however, data are of variable quality. Guidance can be drawn from the existing literature relating to best practice options for diaper area cleansing methods, diaper type selection, and use of barrier creams. More research is required into the benefit or otherwise of diaper-free time.
CONCLUSIONS
Super-absorbent diapers reduce moisture at skin level and reduce diaper dermatitis. Barrier creams carry benefit both in prevention and cure but do not provide a substitute for frequent diaper changes. The literature does not demonstrate superiority of one cleansing method over another, but neither the use of wipes nor water increases diaper dermatitis prevalence. Further studies are required to explore the potential benefit of diaper-free time, taking due consideration of the practicalities, particularly for vulnerable neonates within the Intensive Care setting.
Topics: Diaper Rash; Diapers, Infant; Humans; Infant; Infant Care; Infant, Newborn; Skin; Skin Care; Skin Physiological Phenomena
PubMed: 30506880
DOI: 10.1111/pde.13714 -
Pediatrics in Review Jan 2021
Topics: Diaper Rash; Female; Humans; Infant
PubMed: 33386309
DOI: 10.1542/pir.2018-0141 -
Pediatric Annals Jan 2000
Review
Topics: Administration, Topical; Candidiasis; Diagnosis, Differential; Diaper Rash; Humans; Infant; Infant Care; Infant, Newborn; Vitamin A; Zinc Oxide
PubMed: 10941767
DOI: 10.3928/0090-4481-20000101-09 -
Journal of Paediatrics and Child Health Oct 2022
Topics: Diagnosis, Differential; Diaper Rash; Humans; Infant
PubMed: 36181438
DOI: 10.1111/jpc.1_15794 -
Journal of Paediatrics and Child Health Oct 2022
Topics: Diagnosis, Differential; Diaper Rash; Humans; Infant
PubMed: 34697847
DOI: 10.1111/jpc.15794