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Lancet (London, England) Mar 1955
Topics: Burns; Diabetes Mellitus; Dimercaprol; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin
PubMed: 13234426
DOI: 10.1016/s0140-6736(55)90270-1 -
Archives of Environmental Health Dec 1960
Topics: Cadmium; Cadmium Compounds; Cadmium Poisoning; Dimercaprol; Oxides
PubMed: 13764772
DOI: 10.1080/00039896.1960.10662723 -
Intensive Care Medicine 1992In massive arsenic poisoning, the use of hemodialysis and dimercaprol (BAL) therapy is still controversial. Hemodialysis is thought of value only for supportive care....
In massive arsenic poisoning, the use of hemodialysis and dimercaprol (BAL) therapy is still controversial. Hemodialysis is thought of value only for supportive care. BAL therapy has been criticized because of its delayed action, its own toxicity and its possible influence on arsenic clearance during hemodialysis. We studied arsenic kinetics during an acute suicidal intoxication (10 g of sodium arsenate). Treatment included gastric lavage, oral charcoal and supportive measures. Hemodialysis was performed immediately and repeated the next day. BAL therapy was prescribed only on the second day. Cardiovascular collapse, anuria and hepatic disturbance recovered in a few days and the patient could be discharged on the 15th day. Instantaneous serum arsenic hemodialysis clearance was 85 +/- 75 ml/min without previous BAL injection and 87.5 +/- 75 ml/min with a previous 250 mg BAL injection (difference not significant) indicating that BAL did not impede arsenic dialysis. The calculated total hemodialysis clearance of arsenic was higher than mean serum hemodialysis clearance indicating that erythrocyte bound arsenic is also eliminated during dialysis. We propose to consider early hemodialysis as an elimination measure in massive arsenic poisoning and to choose BAL as a chelator when dialysis is required.
Topics: Adult; Arsenic; Arsenic Poisoning; Dimercaprol; Humans; Male; Metabolic Clearance Rate; Poisoning; Renal Dialysis; Suicide, Attempted
PubMed: 1578049
DOI: 10.1007/BF01706427 -
Journal of the American Pharmaceutical... Jul 1958
Topics: Chromatography, Liquid; Dimercaprol; Retinal Degeneration; Sulfhydryl Compounds
PubMed: 13563260
DOI: 10.1002/jps.3030470717 -
Bulletin of the World Health... 1965
Topics: Animals; Antimony; Dimercaprol; Mice; Schistosomiasis
PubMed: 5295004
DOI: No ID Found -
British Medical Journal (Clinical... Apr 1985
Topics: Dimercaprol; Hepatolenticular Degeneration; Humans; Male; Unithiol; Zinc
PubMed: 3921157
DOI: 10.1136/bmj.290.6476.1213-a -
Medical Bulletin (Ann Arbor, Mich.) Nov 1953
Topics: Copper; Dimercaprol; Hepatolenticular Degeneration; Law Enforcement
PubMed: 13122933
DOI: No ID Found -
Late onset of gold-induced thrombocytopenia. With a practical note on the injections of dimercaprol.JAMA Jan 1978
Topics: Aged; Arthritis, Rheumatoid; Dimercaprol; Gold; Humans; Injections, Intramuscular; Male; Thrombocytopenia; Time Factors
PubMed: 579236
DOI: No ID Found -
Clinical Toxicology 1979An unusual method of introducing arsenic to water with homicidal intentions, where five members of the same family were poisoned, is reported. The obvious initial...
An unusual method of introducing arsenic to water with homicidal intentions, where five members of the same family were poisoned, is reported. The obvious initial diagnosis of food poisoning or food allergy was reviewed when the story of noticing an unusual substance in the well was revealed. The patients recovered fully after conventional intramuscular dimercaprol.
Topics: Adult; Arsenic Poisoning; Digestive System; Dimercaprol; Female; Homicide; Humans; Male; Nervous System; Sri Lanka
PubMed: 498726
DOI: 10.3109/15563657908992467 -
Pediatrics May 1988
Topics: Clothing; Dimercaprol; Environmental Exposure; Humans; Infant; Male; Mercury Poisoning
PubMed: 3357743
DOI: No ID Found