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Parasitology Feb 1981The in vitro interaction between rat peritoneal macrophages and Dipetalonema viteae microfilariae in the presence of amicrofilaraemic rat immune serum was studied by...
The in vitro interaction between rat peritoneal macrophages and Dipetalonema viteae microfilariae in the presence of amicrofilaraemic rat immune serum was studied by transmission electron microscopy. The probable sequence of events leading to the killing of D. viteae microfilaria by macrophages is as follows. (a) Rat peritoneal macrophages in the presence of amicrofilaraemic rat immune serum adhere to the parasite surface, (b) the macrophages extend their pseudopodia around the parasite, (c) the 'lysosome-like' granules discharge their contents on to the parasite surface, (d) the lytic activity of these products begins at the parasite surface and (e) subsequent breaking of the microfilarial cuticle occurs, exposing the parasite intracellular material.
Topics: Animals; Dipetalonema; Immunoglobulin E; Macrophages; Male; Microfilariae; Organoids; Rats; Rats, Inbred Strains
PubMed: 7193841
DOI: 10.1017/s003118200004186x -
Acta Tropica Sep 1981The development of Dipetalonema viteae third stage larvae was attempted in vitro. A monophasic culture system consisting of BHK-21 medium supplemented with 10%...
The development of Dipetalonema viteae third stage larvae was attempted in vitro. A monophasic culture system consisting of BHK-21 medium supplemented with 10% tryptose-phosphate broth and 15% fresh jird serum allowed the growth of previously in vivo triggered larvae, but not of those isolated from ticks. The larvae could complete their third moult and grew on a fourth stage larvae up to 5 mm. This development was comparable to that observed in vivo. The presence of an irradiated hamster kidney cell feeder layer could replace an in vivo trigger. The development of the infective larvae took place up to the third moult. Some larvae completed the moult to the fourth stage and reached a maximum length of 3 mm after 14 days. These culture systems offer the possibility to study in vitro the complete development of the infective larvae to fourth stage larvae.
Topics: Animals; Blood; Cricetinae; Culture Media; Dipetalonema; Gerbillinae; Larva; Male; Mesocricetus; Ticks
PubMed: 6118032
DOI: No ID Found -
Zhongguo Xue Xi Chong Bing Fang Zhi Za... Nov 2021ES-62 is a phosphorylcholine-containing, 62 kDa glycoprotein derived from the excretory-secretory product of , which is effective for the prevention and treatment of... (Review)
Review
ES-62 is a phosphorylcholine-containing, 62 kDa glycoprotein derived from the excretory-secretory product of , which is effective for the prevention and treatment of immune dysregulation diseases through triggering activation of immune cells, such as dendritic cells, mononuclear macrophages and regulatory B cells and mediating immune responses. Recently, the role of the ES-62 protein in the management of allergic, autoimmune and metabolic diseases has been paid much attention. This review summarizes the regulatory role of the ES-62 protein in immune dysregulation diseases and the underlying mechanisms, so as to provide insights into future experimental studies.
Topics: Acanthocheilonema; Animals; Dipetalonema; Glycoproteins; Helminth Proteins; Phosphorylcholine
PubMed: 35537846
DOI: 10.16250/j.32.1374.2021141 -
The American Journal of Tropical... Mar 1975Morphologic features of the adult female Dipetalonema streptocerca and microfilariae are described and illustrated from serial paraffin sections of biopsied skin from...
Morphologic features of the adult female Dipetalonema streptocerca and microfilariae are described and illustrated from serial paraffin sections of biopsied skin from eight Africans. Characteristic features include a maximum diameter of 85 microns, a thin, smooth cuticle, and uteri that fill the body cavity. D. streptocerca is briefly compared to Onchocerca volvulus.
Topics: Animals; Dipetalonema; Female; Skin
PubMed: 1168032
DOI: 10.4269/ajtmh.1975.24.264 -
Journal of the American Veterinary... Mar 1971
Topics: Acid Phosphatase; Animals; Diagnosis, Differential; Dipetalonema; Dirofilariasis; Dog Diseases; Dogs; Female; Filarioidea; Histocytochemistry; Male; Nematode Infections
PubMed: 5101887
DOI: No ID Found -
Journal of Medical Primatology Aug 2023We report two cases of disseminated hyperinfection by filariae in free-living primates Saimiri sciureus and Saguinus niger from eastern Amazon. Histopathological...
We report two cases of disseminated hyperinfection by filariae in free-living primates Saimiri sciureus and Saguinus niger from eastern Amazon. Histopathological examination showed the presence of Dipetalonema gracile microfilariae in blood, liver, lungs, spleen, small intestine, kidney, brain, liver, and adults in peritoneal thoracic cavity.
Topics: Animals; Saimiri; Dipetalonema
PubMed: 37329235
DOI: 10.1111/jmp.12658 -
Acta Tropica Sep 1981
Topics: Animals; Cytotoxicity, Immunologic; Dipetalonema; Gerbillinae; Immune Sera; In Vitro Techniques; Larva
PubMed: 6118041
DOI: No ID Found -
The Journal of Parasitology Feb 1984
Comparative Study
Topics: Animals; Cats; Dipetalonema; Dipetalonema Infections; Dogs; Female; Filariasis; Gerbillinae; Male; Microfilariae
PubMed: 6539822
DOI: No ID Found -
Experimental Parasitology Jun 1975
Topics: Animals; Blood; Cricetinae; Dipetalonema; Dipetalonema Infections; Female; Filariasis; Injections, Subcutaneous; Larva; Male; Ticks
PubMed: 1168583
DOI: 10.1016/0014-4894(75)90005-3 -
The Journal of Small Animal Practice Apr 1981
Topics: Animals; Blood; Dipetalonema; Dipetalonema Infections; Dog Diseases; Dogs; Filariasis; Male; Microfilariae; Nigeria
PubMed: 7194948
DOI: 10.1111/j.1748-5827.1981.tb01406.x