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Tropical Medicine and Parasitology :... Mar 1988The susceptibility of hosts to filarial infection during pregnancy and lactation was studied using Dipetalonema viteae in Mastomys natalensis as working model. Though no...
The susceptibility of hosts to filarial infection during pregnancy and lactation was studied using Dipetalonema viteae in Mastomys natalensis as working model. Though no difference in prepatency could be observed yet significantly higher density of microfilaraemia than controls was detected in both pregnant and lactating groups. Extended duration of patency was also found in both pregnant and lactating animals. On autopsy, animals exposed at the time of pregnancy or lactation revealed significantly higher recovery of adult worms as compared to normal controls. Thus pregnancy and/or lactation may lead to higher density and duration of microfilaraemia and enhanced establishment of adult worms in female mastomys which are otherwise less susceptible to filarial infection.
Topics: Animals; Dipetalonema; Dipetalonema Infections; Disease Models, Animal; Disease Susceptibility; Female; Filariasis; Lactation; Muridae; Pregnancy; Pregnancy Complications, Infectious
PubMed: 3387824
DOI: No ID Found -
The Southeast Asian Journal of Tropical... Mar 1980
Topics: Animals; Dipetalonema; Dipetalonema Infections; Female; Filariasis; Haplorhini; Malaysia; Male; Monkey Diseases; Species Specificity
PubMed: 6773151
DOI: No ID Found -
Tropical Diseases Bulletin Dec 1971
Review
Topics: Adolescent; Adult; Animals; Ascariasis; Ascaridia; Cats; Child; Child, Preschool; Dipetalonema; Dogs; Dracunculiasis; Enterobius; Female; Filariasis; Filarioidea; Helminthiasis; Hookworm Infections; Humans; Loa; Male; Mansonella; Nematode Infections; Oesophagostomiasis; Onchocerciasis; Oxyuriasis; Spiruroidea; Strongyloidiasis; Wuchereria
PubMed: 4260297
DOI: No ID Found -
American Journal of Veterinary Research Nov 1983Six male and 6 female Beagles, 6 to 7 months old, were allotted to 2 groups: group I--inoculated subcutaneously with 30 Dipetalonema reconditum infective larvae/dog, and...
Six male and 6 female Beagles, 6 to 7 months old, were allotted to 2 groups: group I--inoculated subcutaneously with 30 Dipetalonema reconditum infective larvae/dog, and group II--noninoculated controls. Group comparisons were made in regard to hematologic values, Knott test results, body weights, blood urea nitrogen, total serum protein, serum albumin and alanine aminotransferase and creatine kinase activities. Routine urinalysis data were compared at 1 week before and at 28 weeks after the inoculations. Mean total leukocyte counts were significantly (P less than 0.05) greater in group I dogs than in group II dogs at postinoculation weeks (PIW) 4, 5, and 7 to 12, and mean eosinophil counts were significantly greater in group I dogs at PIW 3 to 11, 13 to 15, 20, and 23 to 24. Microfilariae were detected as early as the 10th week and sporadically thereafter. Only 1 D reconditum adult worm was recovered from all of the inoculated dogs. Five other dogs (group III) with chronic, patient experimentally induced dipetalonemiasis, were evaluated with the same tests at PIW 70 to 89. Eosinophilia (greater than 750 cells/microliter) was present in 4 of 5 dogs; lymphocytosis (greater than 4,800 cells/microliter) was evident in 1 dog. Proteinuria (greater than or equal to 30 mg/dl) was detected in 3 of 4 dogs with chronic dipetalonemiasis.
Topics: Animals; Dipetalonema; Dipetalonema Infections; Dog Diseases; Dogs; Eosinophilia; Female; Filariasis; Glomerulonephritis; Male; Proteinuria
PubMed: 6685983
DOI: No ID Found -
Systematic Parasitology Mar 2019Although little studied, infections with nematodes of the Onchocercidae Leiper, 1911, predominated by the genera Dipetalonema Diesing, 1861 and Mansonella Faust, 1929,...
Although little studied, infections with nematodes of the Onchocercidae Leiper, 1911, predominated by the genera Dipetalonema Diesing, 1861 and Mansonella Faust, 1929, are frequent in wild primates and human populations in the Neotropical forest areas. This study reports natural infections with Dipetalonema freitasi Bain, Diagne & Muller, 1987 and D. gracile (Rudolphi, 1809) in two free-living species of pitheciid primates, extending the known geographical distribution of these species to the forest of the Peruvian Amazon. Adult worms were recovered from the thoracic and abdominal cavities of two species of monkeys, Pithecia monachus monachus (É. Geoffroy Saint-Hilaire) and Cacajao calvus ucayalii (Thomas) (Primates: Pitheciidae), collected along the Yavari-Mirin River basin and analysed via light and scanning electron microscopy. Both host species represent new host records for D. freitasi and D. gracile. Morphometric data are also presented for the sampled filarial worms in addition to morphological details obtained through light and electron microscopy examination of D. freitasi specimens.
Topics: Abdominal Cavity; Animals; Microscopy, Electron, Scanning; Nematoda; Pitheciidae; Species Specificity; Thoracic Cavity
PubMed: 30747402
DOI: 10.1007/s11230-019-09838-y -
Clinical and Experimental Immunology Jan 1981Infective larvae of did not reach maturity in inbred Fischer rats. However, female adults of when transplanted surgically into Fischer rats established and the...
Dipetalonema viteae infective larvae reach reproductive maturity in rats immunodepressed by prior exposure to Schistosoma mansoni or its products and in congenitally athymic rats.
Infective larvae of did not reach maturity in inbred Fischer rats. However, female adults of when transplanted surgically into Fischer rats established and the resulting microfilaraemia from the transplanted worms persisted for about 120 days after infection. Sequential dissections showed that some of the female worms transplanted remained viable in rats for about 35 days after infection. After inoculation of infective larvae into rats a varying number transformed into stage-4 larvae but they did not develop into adult worms and were killed. However, when the rats were immunodepressed non-specifically by a pre-existing infection or by treatment with -derived substance(s), a number of stage-4 larvae renewed their development and reached sexual maturity. These worms produced microfilariae which were observed in the peripheral blood for about 40 days. The effect of previous infection with on the survival and growth of in Fischer rats depends greatly on the relative timing of infection because infective larvae of reached maturity only when rats were inoculated with infective larvae after 15 days of infection but not after 21 or 28 days of infection. will also develop to maturity in congenitally athymic rats. In congenitally athymic rats (Nu/Nu) each given 75 infective larvae, both the microfilaraemia and adult worm recovery at post-mortem were higher than those which resulted in Nu/Nu rats given an infection of 200 larvae. These experiments show that in rats innate immunity to this filarial nematode reflects a very rapidly induced acquired immunity which kills the parasite before it reaches maturity.
Topics: Animals; Dipetalonema; Dipetalonema Infections; Filariasis; Immune Tolerance; Larva; Male; Rats; Rats, Inbred Strains; Schistosoma mansoni; Schistosomiasis; T-Lymphocytes; Time Factors
PubMed: 6972836
DOI: No ID Found -
The Journal of Parasitology Feb 1974
Topics: Adipose Tissue; Animals; Ataxia; Brain; Central Nervous System Diseases; Dipetalonema; Female; Gerbillinae; Hemiplegia; Injections, Subcutaneous; Larva; Male; Muscles; Myocardium; Nematode Infections; Omentum; Paraplegia; Rodent Diseases; Spinal Cord; Spleen; Ticks; Time Factors
PubMed: 4856033
DOI: No ID Found -
The American Journal of Tropical... Mar 1979Native LVG strain hamsters were infected with Dipetalonema viteae by the surgical implantation of adult worms. Groups of hamsters received either 50 male, 50 female, 50...
Native LVG strain hamsters were infected with Dipetalonema viteae by the surgical implantation of adult worms. Groups of hamsters received either 50 male, 50 female, 50 male plus 50 female or 25 male plus 25 female worms per hamster. Approximately 50% of the transferred worms became established in the recipient hosts regardless of the number or sex of the worms implanted. Microfilaremia occurred in recipient hamsters within 1 week after the transfer of female or male plus female worms. This microfilaremia became negative on week 9 post-transfer and no microfilaremia developed in these hamsters following a secondary challenge infection of male plus female worms. Hamsters whose primary infection consisted solely of male worms developed a microfilaremia when challenged with male plus female worms.
Topics: Animals; Cricetinae; Dipetalonema; Dipetalonema Infections; Female; Filariasis; Immunity; Male; Mesocricetus; Rodent Diseases; Sex Factors
PubMed: 572146
DOI: 10.4269/ajtmh.1979.28.216 -
Australian Veterinary Journal Jan 1973
Review
Topics: Acid Phosphatase; Animals; Blood; Centrifugation; Diagnosis, Differential; Dipetalonema; Dirofilariasis; Dog Diseases; Dogs; Female; Filarioidea; Filtration; Hematocrit; Histocytochemistry; Male; Methylene Blue; Nematode Infections; Saponins
PubMed: 4571749
DOI: 10.1111/j.1751-0813.1973.tb14671.x -
International Journal For Parasitology Apr 1985
Topics: Animals; Cytochrome P-450 Enzyme System; Dipetalonema; Dipetalonema Infections; Filariasis; Microsomes, Liver; Mixed Function Oxygenases; Muridae
PubMed: 4039707
DOI: 10.1016/0020-7519(85)90083-9