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Annales de Chirurgie Mar 1961
Topics: Diuresis
PubMed: 13731096
DOI: No ID Found -
The American Journal of Physiology Sep 1956
Topics: Animals; Diuresis; Epinephrine; Hypoxia; Rats
PubMed: 13362585
DOI: 10.1152/ajplegacy.1956.187.1.32 -
Surgical Forum 1957
Topics: Chlorpromazine; Diuresis; Hemorrhage; Hypotension
PubMed: 13433306
DOI: No ID Found -
Journal of the American Society of... Jan 2015The sodium glucose co-transporter 2 (SGLT2) inhibitors represent a promising treatment option for diabetes and its common comorbidity, hypertension. Emerging data... (Review)
Review
The sodium glucose co-transporter 2 (SGLT2) inhibitors represent a promising treatment option for diabetes and its common comorbidity, hypertension. Emerging data suggests that the SGLT2 inhibitors provide a meaningful reduction in blood pressure, although the precise mechanism of the blood pressure drop remains incompletely elucidated. Based on current data, the blood pressure reduction is partially due to a combination of diuresis, nephron remodeling, reduction in arterial stiffness, and weight loss. While current trials are underway focusing on cardiovascular endpoints, the SGLT2 inhibitors present a novel treatment modality for diabetes and its associated hypertension as well as an opportunity to elucidate the pathophysiology of hypertension in diabetes.
Topics: Blood Pressure; Diabetic Angiopathies; Diuresis; Humans; Hypertension; Kidney; Natriuresis; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Vascular Stiffness
PubMed: 25537461
DOI: 10.1016/j.jash.2014.11.001 -
Hypertension (Dallas, Tex. : 1979) Nov 2013
Topics: Animals; Diuresis; Gastrins; Kidney; Natriuresis; Receptors, Dopamine D1
PubMed: 24019398
DOI: 10.1161/HYPERTENSIONAHA.113.01799 -
Nature Oct 1978
Topics: Animals; Diuresis; Kidney Tubules, Proximal; Natriuresis; Rats; Stimulation, Chemical; Vanadium
PubMed: 703847
DOI: 10.1038/275768a0 -
Hormone Research 1998The maintenance of hydromineral homeostasis depends on the coordinated action of arginine vasopressin (AVP), atrial natriuretic peptide (ANP), the... (Review)
Review
The maintenance of hydromineral homeostasis depends on the coordinated action of arginine vasopressin (AVP), atrial natriuretic peptide (ANP), the renin-angiotensin-aldosterone system and other recently identified endocrine or paracrine hormones. Several reports have pointed out the changes in urinary excretion and osmolality during the sleep-wake cycle and the rapid eye movement (REM)-non(N)REM sleep cycles. No such changes occur for ANP levels which have a flat profile over 24 h. The pulsatile fluctuations of AVP are described as random. The ultradian rhythm of plasma renin activity (PRA) depends on the regularity of the REM-NREM sleep cycles and the nocturnal curves reflect all disturbances in the internal sleep structure. A study with a shift in the normal sleep time clearly demonstrated that both PRA and aldosterone oscillations are sleep-stage dependent. These hormones could account for the ultradian variations in renal function. The nocturnal oscillations in sympathovagal balance may play an additional role. It is suggested that a central generator synchronizes endocrine, renal, autonomic and sleep processes.
Topics: Activity Cycles; Diuresis; Hormones; Humans; Natriuresis; Renin-Angiotensin System; Sympathetic Nervous System; Water-Electrolyte Balance
PubMed: 9550113
DOI: 10.1159/000023159 -
Neuroscience Letters Dec 1989The role of oropharyngeal mechanisms in body water regulation was studied in 12 human males by measuring urine output and osmolality before and after drinking a very...
The role of oropharyngeal mechanisms in body water regulation was studied in 12 human males by measuring urine output and osmolality before and after drinking a very small volume of distilled water (0.15 ml/kg b.w.t.). Hypotonic diuresis was resulted only in the subjects (n = 6) who drank only sufficient water to keep their oropharynx moist continually over a 20 min period but not in those who (n = 6) drank the same volume of water within several seconds. Sham verbal instructions on drinking induced no changes in subjects examined. These results suggest that oropharyngeal afferents alone, and neither gastric afferents nor psychosomatic effects, may account for hypotonic diuresis following water intake in man.
Topics: Adult; Diuresis; Drinking Behavior; Humans; Male; Oropharynx; Water
PubMed: 2616050
DOI: 10.1016/0304-3940(89)90792-1 -
American Journal of Physiology. Renal... Jan 2012
Topics: Diuresis; Female; Humans; Male; Natriuresis; Renin-Angiotensin System; Sleep Deprivation
PubMed: 22071245
DOI: 10.1152/ajprenal.00602.2011 -
Journal of Magnetic Resonance Imaging :... Jun 2003To refine and evaluate methods for analysis of renal blood oxygenation level dependent (BOLD) MRI data.
PURPOSE
To refine and evaluate methods for analysis of renal blood oxygenation level dependent (BOLD) MRI data.
MATERIALS AND METHODS
Color R2* maps and regions-of-interest (ROIs) on the borderline between cortex and medulla were applied to renal BOLD MRI data of a group of 13 young female subjects.
RESULTS
The distribution of R2* within the kidneys was heterogeneous and the response of human kidneys to water diuresis was patchy. R2* values at the cortico-medullary border region have a smaller variation than in wider cortical or medullary regions and are sensitive to physiological changes produced by water diuresis.
CONCLUSION
These methods provide improved visualization of the regional distribution of R2* and its variations and more precise quantification of the changes in renal R2* produced by water diuresis.
Topics: Adult; Body Water; Diuresis; Female; Humans; Kidney; Magnetic Resonance Imaging; Reference Values
PubMed: 12766897
DOI: 10.1002/jmri.10314