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Clinical Gastroenterology and... Dec 2016Symptomatic uncomplicated diverticular disease is considered to be a discreet clinical entity distinct from irritable bowel syndrome (IBS), but population-based data are...
BACKGROUND & AIMS
Symptomatic uncomplicated diverticular disease is considered to be a discreet clinical entity distinct from irritable bowel syndrome (IBS), but population-based data are unavailable. We aimed to investigate the prevalence and location of diverticulosis in the general population, and its association with colonic symptoms and mental health. We propose that individuals with diverticulosis would report more constipation and IBS.
METHODS
We performed a population-based study of randomly selected adults born in Sweden (age, 18-70 y; 57.2% women); 745 received a gastroenterology consultation, completed validated abdominal symptom and mental health questionnaires, and were examined by colonoscopy. Logistic regression was used to calculate the associations between diverticulosis and age, sex, gastrointestinal symptoms, anxiety, depression, and self-rated health.
RESULTS
Among the 742 participants (54.6% women), 130 (17.5%) had diverticulosis. Age was the strongest predictor of diverticulosis (P < .001), and diverticulosis was rare in participants younger than 40 years (0.7%). All participants with diverticulosis had sigmoid involvement. Participants with diverticulosis were more likely to report loose stools (odds ratio [OR], 1.88; 95% confidence interval [CI], 1.20-2.96), urgency (OR, 1.64; 95% CI, 1.02-2.63), passing mucus (OR, 2.26; 95% CI, 1.08-4.72), and a high stool frequency (OR, 2.02; 95% CI, 1.11-3.65). Diverticulosis was associated with abdominal pain (OR, 2.10; 95% CI, 1.01-4.36; P = .047) and diarrhea-predominant IBS (OR, 9.55; 95% CI, 1.08-84.08; P = .04) in participants older than 60 years. The presence of anxiety and depression and self-rated health were similar in participants with and without diverticulosis.
CONCLUSIONS
The prevalence of diverticulosis is age-dependent. Diverticulosis is associated with diarrhea in subjects across all age ranges. In subjects older than age 60, diverticulosis is associated with abdominal pain and diarrhea-predominant IBS.
Topics: Abdominal Pain; Adolescent; Adult; Age Factors; Aged; Diarrhea; Diverticulum; Female; Humans; Male; Middle Aged; Prevalence; Risk Factors; Surveys and Questionnaires; Sweden; Young Adult
PubMed: 27353142
DOI: 10.1016/j.cgh.2016.06.014 -
Gastroenterologia Y Hepatologia Mar 2022
Topics: Aged, 80 and over; Diverticulum; Duodenal Diseases; Female; Gastrointestinal Hemorrhage; Gastroscopy; Humans; Stomach Diseases
PubMed: 33272736
DOI: 10.1016/j.gastrohep.2020.07.029 -
ANZ Journal of Surgery Jul 2022
Topics: Diverticulum; Humans; Intestinal Obstruction; Intestine, Small
PubMed: 34859945
DOI: 10.1111/ans.17408 -
The Journal of the American Osteopathic... Apr 1988
Review
Topics: Diverticulum; Female; Humans; Jejunal Diseases; Middle Aged
PubMed: 3130345
DOI: No ID Found -
European Journal of Medical Research Aug 2005Although often incidentally found in the radiological examination of the small intestine, some patients with diverticula suffer from complications, that may lead to...
Although often incidentally found in the radiological examination of the small intestine, some patients with diverticula suffer from complications, that may lead to surgical intervention. Contrast study of the small intestine by enteroclysis is the method of choice to determine jejunal diverticula. We report a case of symptomatic proximal jejunal diverticulosis in a 74 year old patient who presented with diffuse abdominal pain. The clinical significance, diagnostic evaluation and treatment of jejunal diverticulosis are reviewed.
Topics: Aged; Anti-Bacterial Agents; Diverticulum; Humans; Jejunal Diseases; Jejunum; Male
PubMed: 16131478
DOI: No ID Found -
International Surgery Feb 1978Diverticulosis of the jejunum is an uncommon condition. We found four patients with such diverticula among 40,341 hospital admissions. All four patients presented with...
Diverticulosis of the jejunum is an uncommon condition. We found four patients with such diverticula among 40,341 hospital admissions. All four patients presented with acute volvulus of the small bowel. It is suggested that the diverticula bearing segment becomes heavier due to the diverticula and the semisolid jejunal contents consisting of roughage, millet and cereals in the staple diet of our patients. Both factors contribute to small bowel volvulus. Jejunal diverticula may be missed because they are buried between the leaves of mesentery or adherent loops of jejunum. With a patient has vague abdominal symptoms, the possibility of jejunal diverticula should be considered.
Topics: Adult; Diverticulum; Humans; Intestinal Obstruction; Jejunum; Male
PubMed: 415996
DOI: No ID Found -
Canadian Journal of Surgery. Journal... May 1980Jejunal diverticulosis is an uncommon condition, but it is often associated with a number of symptoms including postprandial abdominal pain, distension, flatulence,...
Jejunal diverticulosis is an uncommon condition, but it is often associated with a number of symptoms including postprandial abdominal pain, distension, flatulence, borborygmus, nausea, vomiting, diarrhea and constipation and with complications such as vomiting blood or coffee grounds material, melena and shock. The authors report such a condition in a 71-year-old man. Resection is the treatment of choice for relieving symptoms, and for preventing or treating complications.
Topics: Aged; Diverticulum; Humans; Jejunal Diseases; Male
PubMed: 6769577
DOI: No ID Found -
Polski Tygodnik Lekarski (Warsaw,... Jun 1980
Review
Topics: Aged; Colonic Neoplasms; Constipation; Diagnosis, Differential; Diverticulum, Colon; Humans; Intestinal Obstruction; Middle Aged
PubMed: 6997846
DOI: No ID Found -
British Medical Journal Jun 1979
Topics: Diverticulum; Humans; Music
PubMed: 111760
DOI: 10.1136/bmj.1.6179.1711 -
Gastroenterologia Y Hepatologia Feb 2023
Topics: Humans; Colitis; Diverticulum
PubMed: 34793896
DOI: 10.1016/j.gastrohep.2021.11.003