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Revista Espanola de Las Enfermedades... Aug 1987
Review
Topics: Adult; Aged; Appendix; Cecal Diseases; Diverticulitis; Diverticulum; Female; Humans; Male; Middle Aged
PubMed: 3116614
DOI: No ID Found -
The American Journal of Case Reports Oct 2021BACKGROUND Eosinophilic gastroenteritis is a broad classification of disease characterized by eosinophilic infiltration of the gastrointestinal tract in the absence of a...
BACKGROUND Eosinophilic gastroenteritis is a broad classification of disease characterized by eosinophilic infiltration of the gastrointestinal tract in the absence of a stimulatory cause. Given the ability of eosinophilic gastroenteritis to affect the entire gastrointestinal tract, it can present in a variety of ways, from chronic intermittent pain to mechanical obstruction. We present a rare case in which eosinophilic gastroenteritis of the jejunum led to small bowel diverticulosis and volvulus, requiring surgery. CASE REPORT An 83-year-old woman with a history of chronic abdominal pain, nausea, and early satiety presented to our clinic after a thorough gastrointestinal workup and radiologic diagnosis of partial midgut volvulus. She underwent an exploratory laparotomy and was found to have normal rotational anatomy with prominent small bowel diverticulosis. A section of 70 cm of proximal jejunum was resected, encompassing all visible diverticula, and a primary anastomosis was performed. The patient recovered without complication. She was seen at follow-up with complete resolution of her presenting symptoms. CONCLUSIONS We propose that this patient's pathology was caused by chronic intermittent obstructions related to eosinophilic gastroenteritis, leading to repeated periods of increased intraluminal pressure and severe small bowel diverticulosis. This case highlights the importance of maintaining an index of suspicion for small bowel diverticulosis in the setting of chronic eosinophilic gastroenteritis.
Topics: Aged, 80 and over; Diverticulum; Enteritis; Eosinophilia; Female; Gastritis; Humans; Intestinal Volvulus
PubMed: 34608111
DOI: 10.12659/AJCR.933180 -
The American Journal of Roentgenology,... Oct 1968
Topics: Diverticulum; Humans; Male; Middle Aged; Ureteral Diseases; Urography
PubMed: 4971873
DOI: 10.2214/ajr.104.2.364 -
Southern Medical Journal Jul 1981
Topics: Aged; Diverticulum; Female; Humans; Ileal Diseases; Jejunal Diseases; Male; Middle Aged
PubMed: 6789452
DOI: 10.1097/00007611-198107000-00007 -
Clinical Radiology Oct 1974
Topics: Black People; Diverticulum; England; Fallopian Tubes; Female; Genital Diseases, Female; Humans; Hysterosalpingography; Infertility, Female; Jamaica; Pregnancy; Pregnancy, Ectopic; Tuberculosis, Female Genital; White People
PubMed: 4216440
DOI: 10.1016/s0009-9260(74)80148-0 -
European Journal of Gastroenterology &... Dec 2021Diverticulosis affects approximately 60% of population after 60th year of age. Diverticular disease is symptomatic diverticulosis characterized by abdominal pain,...
INTRODUCTION
Diverticulosis affects approximately 60% of population after 60th year of age. Diverticular disease is symptomatic diverticulosis characterized by abdominal pain, flatulence and bloating, and bowel habits change. Age and lifestyle are risk factors for diverticulosis, additionally genetic predisposition is postulated. The aim of the study was to assess whether tissue inhibitors of matrix metalloproteinase (TIMP) 1 rs4898 and TIMP2 rs8179090 genetic variants are related to colonic diverticulosis.
METHODS
The study included 220 patients, 100 with colon diverticulosis diagnosed on colonoscopy and 120 controls. TIMP1 rs4898 and TIMP2 rs8179090 variants were examined using PCR-restriction fragments length polymorphism from a blood sample.
RESULTS
Allele T of TIMP1 rs4898 was more frequent in male patients with diverticulosis than in controls (P < 0.01), whereas in women there were no differences in its distribution, both in heterozygotes and homozygotes or in homozygotes separately, proving a recessive effect. TIMP2 s8179090 allele G frequency was 0.95 in cases and controls, there were no CC homozygotes identified, and no associations with diverticulosis showed.
CONCLUSION
TIMP1 rs4898 allele T may be a genetic determinant of the risk of diverticulosis in men.
Topics: Alleles; Diverticulum; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Male; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2
PubMed: 33731593
DOI: 10.1097/MEG.0000000000002122 -
A Small Colonic Pedunculated Polypoid Lesion in the Context of Diverticulosis: The Ring-a-bell Sign.Journal of Gastrointestinal and Liver... Mar 2022
Topics: Colonic Diseases; Diverticulosis, Colonic; Diverticulum; Humans; Polyps
PubMed: 35306552
DOI: 10.15403/jgld-4010 -
Khirurgiia Mar 1988
Review
Topics: Diverticulum; Diverticulum, Colon; Female; Humans; Intestinal Diseases; Intestine, Large; Male
PubMed: 3133520
DOI: No ID Found -
Minerva Chirurgica May 1995The jejunal diverticula are a rare pathology, they are verifiable with an incidence from 0.06 to 1.3% autoptical reports. Furthermore, only 10-40% of them are... (Review)
Review
The jejunal diverticula are a rare pathology, they are verifiable with an incidence from 0.06 to 1.3% autoptical reports. Furthermore, only 10-40% of them are symptomatic. Nevertheless, in this case the beginning is often acute because of a perforation or a hemorrhage. In both cases the medical therapy is associated with a mortality rate which is too high to be acceptable, so therefore, emergency surgery is the only possible choice. The authors present a clinical case resulting from their observation with an acute beginning, this case is used as a starting point for an accurate review of the international literature on the subject. The purpose of this study is to contribute to a correct understanding and approach to the problem, above all through an exact preoperative diagnosis so that unnecessary delays in surgery may be avoided when a patient's life is at risk.
Topics: Diverticulum; Female; Humans; Jejunal Diseases; Middle Aged
PubMed: 7478063
DOI: No ID Found -
Digestive Diseases and Sciences Sep 2016Diverticulosis and its complications are important healthcare problems in the USA and throughout the Western world. While mechanisms as to how diverticulosis occurs have...
BACKGROUND
Diverticulosis and its complications are important healthcare problems in the USA and throughout the Western world. While mechanisms as to how diverticulosis occurs have partially been explored, few studies examined the relationship between colonic gases such as methane and diverticulosis in humans.
AIM
This study aimed to demonstrate a significant relationship between methanogenic Archaea and development of diverticulosis.
METHODS
Subjects who consecutively underwent hydrogen breath test at Rush University Medical Center between 2003 and 2010 were identified retrospectively through a database. Medical records were reviewed for presence of a colonoscopy report. Two hundred and sixty-four subjects were identified who had both a breath methane level measurement and a colonoscopy result. Additional demographic and clinical data were obtained with chart review.
RESULTS
Mean breath methane levels were higher in subjects with diverticulosis compared to those without diverticulosis (7.89 vs. 4.94 ppm, p = 0.04). Methane producers (defined as those with baseline fasting breath methane level >5 ppm) were more frequent among subjects with diverticulosis compared to those without diverticulosis (50.9 vs. 34 %, p = 0.0025). When adjusted for confounders, breath methane levels and age were the two independent predictors of diverticulosis on colonoscopy with logistic regression modeling.
CONCLUSIONS
Methanogenesis is associated with the presence of diverticulosis. Further studies are needed to confirm our findings and prospectively evaluate a possible etiological role of methanogenesis and methanogenic archaea in diverticulosis.
Topics: Age Factors; Antihypertensive Agents; Breath Tests; Case-Control Studies; Celiac Disease; Colonoscopy; Constipation; Diverticulum; Female; Humans; Hypertension; Logistic Models; Male; Methane; Middle Aged; Retrospective Studies; Rheumatic Diseases
PubMed: 27129485
DOI: 10.1007/s10620-016-4174-6