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The Israel Medical Association Journal... Oct 2017Dupuytren's disease is a common benign fibromatosis of the palmar and digital fascia. The exact pathophysiology and epidemiology of this condition have not been entirely... (Review)
Review
Dupuytren's disease is a common benign fibromatosis of the palmar and digital fascia. The exact pathophysiology and epidemiology of this condition have not been entirely identified. Pathologic fibrous bands cause a flexion contracture of the metacarpal phalangeal joints and proximal interphalangeal joint. Treatment includes fasciectomy, needle fasciotomy, and enzymatic fasciectomy.
Topics: Dupuytren Contracture; Fasciotomy; Humans; Treatment Outcome
PubMed: 29103246
DOI: No ID Found -
Hand Clinics Aug 2023Dupuytren disease is a common pathologic condition that can be especially challenging to hand surgeons in recurrent or severe contractures. Recurrence risk may be... (Review)
Review
Dupuytren disease is a common pathologic condition that can be especially challenging to hand surgeons in recurrent or severe contractures. Recurrence risk may be reduced with a variety of techniques, including skin grafting, external fixator application, radiation, and many others described in this article. Management of recurrence requires special attention to anatomy at risk. Adjuvant therapy may help to prevent the progression or recurrence of severe disease.
Topics: Humans; Dupuytren Contracture; Skin Transplantation; Skin; Treatment Outcome
PubMed: 37453772
DOI: 10.1016/j.hcl.2023.03.006 -
MMW Fortschritte Der Medizin Oct 2022
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Workplace Health & Safety Mar 2017Dupuytren's disorder is considered a genetic disorder and therefore not covered under workers' compensation. Personal risk factors include workers of Northern European... (Review)
Review
Dupuytren's disorder is considered a genetic disorder and therefore not covered under workers' compensation. Personal risk factors include workers of Northern European descent and workers that are older than 50 years. However, new evidence has shown that certain occupational activities may increase the risk of developing this disorder. This article is a review of the literature with a case study. Work-related and personal risk factors are explored, as well as interventions and return to work recommendations.
Topics: Dupuytren Contracture; Female; Humans; Male; Middle Aged; Occupational Diseases; Risk Factors; Vibration; Workers' Compensation
PubMed: 28068478
DOI: 10.1177/2165079916680215 -
Southern Medical Journal Aug 1991Dupuytren's contracture is a disease of the palmar and digital fascia that results in a flexion deformity of the fingers. Although the first case was reported more than... (Review)
Review
Dupuytren's contracture is a disease of the palmar and digital fascia that results in a flexion deformity of the fingers. Although the first case was reported more than 350 years ago, many questions remain unanswered. With our present state of knowledge, treatment remains empiric and operative intervention is the only successful mode of treatment. Controversies continue over the type of procedure used, as well as its timing. In light of the high rate of recurrence of flexion contractures after apparently successful operations, current research is being directed toward identifying a biochemical or histologic marker to indicate the probability of recurrence.
Topics: Dupuytren Contracture; Humans
PubMed: 1882276
DOI: 10.1097/00007611-199108000-00011 -
Hand Clinics Aug 2018This article discusses limited fasciectomy for Dupuytren contracture, reviews the literature to list common complications, addresses the observations that need to be... (Review)
Review
This article discusses limited fasciectomy for Dupuytren contracture, reviews the literature to list common complications, addresses the observations that need to be made after surgery, and systematically reviews the literature for 2 clinical questions: (1) regarding leaving wounds open and (2) the use of postoperative splintage.
Topics: Bandages; Clinical Decision-Making; Dupuytren Contracture; Fasciotomy; Humans; Postoperative Care; Postoperative Complications; Recurrence; Splints
PubMed: 30012295
DOI: 10.1016/j.hcl.2018.04.002 -
The Journal of the American Academy of... 1998Dupuytren's contracture is a fibroproliferative disorder of autosomal dominant inheritance that most commonly affects men over age 60 who are of Scandinavian, Irish, or... (Review)
Review
Dupuytren's contracture is a fibroproliferative disorder of autosomal dominant inheritance that most commonly affects men over age 60 who are of Scandinavian, Irish, or eastern European descent. Local microvessel ischemia in the hand and specific platelet-derived and fibroblast growth factors act at the cellular level to promote the dense myofibroblast population and altered collagen profiles seen in affected tissue. Surgical treatment depends to some degree on patient preference and a clear understanding of the possible complications and considerable postoperative therapy commitment. Operative management is appropriate when metacarpophalangeal or proximal interphalangeal joint contracture exceeds 30 degrees. A volar zigzag Brunner incision in the digit and palm provides reliable exposure and leads to predictable healing in most cases. The mainstay of postoperative hand therapy is early active-flexion range-of-motion exercises to restore grip strength. A nighttime extension splint is often used for several months postoperatively to maintain the correction achieved in the operating room. Early recurrence of disease is most common in individuals with Dupuytren's diathesis; use of full-thickness skin grafts may be helped for these patients.
Topics: Dupuytren Contracture; Humans; Male; Middle Aged; Recurrence; Treatment Outcome
PubMed: 9692938
DOI: 10.5435/00124635-199801000-00003 -
British Medical Journal Sep 1976
Topics: Aged; Dupuytren Contracture; Europe; Humans; Male
PubMed: 974566
DOI: No ID Found -
European Journal of Pediatric Surgery :... Apr 2015Dupuytren contracture of the palm is a relatively common benign fibroproliferative disease of the palmar fascia typically affecting the adult population. There have... (Review)
Review
Dupuytren contracture of the palm is a relatively common benign fibroproliferative disease of the palmar fascia typically affecting the adult population. There have however been several reported cases of Dupuytren contracture in children. We sought to review the literature for Dupuytren contracture and highlight the main clinical features and management of the disease in children.
Topics: Child; Dupuytren Contracture; Hand; Humans
PubMed: 24163199
DOI: 10.1055/s-0033-1357756 -
Deutsches Arzteblatt International Nov 2021The worldwide prevalence of Dupuytren's disease (DD) is 8%. DD is a chronic disease for which there is no cure. Various treatments are available. (Review)
Review
BACKGROUND
The worldwide prevalence of Dupuytren's disease (DD) is 8%. DD is a chronic disease for which there is no cure. Various treatments are available.
METHODS
This review is based on pertinent publications retrieved by a selective search in PubMed and Embase.
RESULTS
Genetic factors account for 80% of the factors involved in causing this disease. Diabetes mellitus, hepatic diseases, epilepsy, and chronic occupational use of vibrating tools are also associated with it. Limited fasciectomy is the most common treatment and is considered the reference standard. Possible complications include persistent numbness in areas where the skin has been elevated, cold sensitivity, and stiffness, with a cumulative risk of 3.6 -39.1% for all complications taken together. The recurrence rate at 5 years is 12-73%. Percutaneous needle fasciotomy is the least invasive method, with more rapid recovery and a lower complication rate than with limited fasciectomy. 85% of patients have a recurrence after an average of 2.3 years. Radiotherapy can be given before contractures arise in patients with high familial risk, or postoperatively in selected patients with a very high individual risk of recurrence.
CONCLUSION
Although DD is not curable, good treatments are available. Recurrences reflect the pathophysiology of the disease and should not be considered complications of treatment. When counseling patients about the available treatment options, particularly the modalities and timing of surgery, the physician must take the patient's degree of suffering into account. Nowadays, fast recovery from surgery and less postoperative pain are a priority for many patients. Different surgical methods can be used in combination. It remains difficult to predict the natural course and the time to postoperative recurrence in individual patients; these matters should be addressed in future studies.
Topics: Dupuytren Contracture; Fasciotomy; Humans; Needles; Orthopedic Procedures; Research Design
PubMed: 34702442
DOI: 10.3238/arztebl.m2021.0325