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The American Surgeon Nov 1967
Topics: Dupuytren Contracture; Fasciotomy; Hand Deformities, Acquired; Humans; Male; Postoperative Care; Postoperative Complications; Splints; Wound Healing
PubMed: 6061280
DOI: No ID Found -
Physiotherapy Oct 1983
Topics: Aged; Dupuytren Contracture; Female; Humans; Male; Postoperative Care
PubMed: 6647594
DOI: No ID Found -
Lancet (London, England) Sep 1972
Topics: Dupuytren Contracture; History, 18th Century; United Kingdom
PubMed: 4115854
DOI: 10.1016/s0140-6736(72)92127-7 -
Lancet (London, England) Sep 1972
Topics: Alkaline Phosphatase; Dupuytren Contracture; History, 19th Century; Humans
PubMed: 4116807
DOI: 10.1016/s0140-6736(72)93051-6 -
The Israel Medical Association Journal... Jun 2008Dupuytren's disease is a fibroproliferative disorder of the palmar fascia that can cause disabling digital contractures. The pathogensis of the disease is still unclear,...
BACKGROUND
Dupuytren's disease is a fibroproliferative disorder of the palmar fascia that can cause disabling digital contractures. The pathogensis of the disease is still unclear, and it afflicts predominantly white males of northern European origin. Gender-related differences of Dupuytren's disease and the distinctive characteristics of the disease in females are not yet well defined.
OBJECTIVES
To evaluate and illustrate the distinctive characteristics of Dupuytren's disease in females.
METHODS
A retrospective study was performed of all female patients with Dupuytren's disease seen and followed at our Hand Surgery Unit over a 20 year period. The study group consisted of 48 women (56 hands). The collected data included clinical and epidemiological features on admission, and outcome of surgical intervention.
RESULTS
Of the 48 women (56 hands) with Dupuytren's disease, 23 (26 hands) underwent limited fasciectomy. The average age at presentation was 60.1 years. A few of the patients originated from Asia and Africa. Manifestations and pattern of the disease were nearly comparable to those observed in the male group, except for a slightly higher incidence of proximal interphalangeal joint contracture in female patients. Generally, females expressed less severe contractures on presentation and a slower progression thereafter. A favorable functional postoperative outcome was observed. Seven patients had minor complications including local hematoma and painful scars. Two patients developed moderate signs of complex regional pain syndrome.
CONCLUSIONS
Further investigations are needed to assess the potential role of androgens in the pathogenesis of Dupuytren's disease, and a possible protective role of estrogenic hormones, rendering Dupuytren's contracture a postmenopausal affliction.
Topics: Adult; Aged; Dupuytren Contracture; Ethnicity; Female; Humans; Israel; Middle Aged; Retrospective Studies; Risk Factors; Time Factors; Treatment Outcome
PubMed: 18669144
DOI: No ID Found -
The Journal of the Arkansas Medical... Jan 2016
Topics: Aged; Dupuytren Contracture; Humans; Male
PubMed: 26817199
DOI: No ID Found -
Indian Journal of Dermatology,... 2010
Review
Topics: Adult; Dupuytren Contracture; Humans; Male; Radiography
PubMed: 20445309
DOI: 10.4103/0378-6323.62985 -
The Journal of Hand Surgery Sep 1996A case report of a 34-year-old black man with Dupuytren's contracture of his left small finger and review of the literature of Dupuytren's disease in the black... (Review)
Review
A case report of a 34-year-old black man with Dupuytren's contracture of his left small finger and review of the literature of Dupuytren's disease in the black population is presented. A high incidence of trauma (54%) was associated with these cases.
Topics: Adult; Black People; Dupuytren Contracture; Humans; Male; Risk Factors
PubMed: 8891992
DOI: 10.1016/s0363-5023(96)80211-5 -
Revista Medica de Chile Sep 2012Dupuytren disease (DD) is a connective tissue disorder that consists in fibromatosis of the palmar and digital fascia (in form of nodules or flanges) that leads to the... (Review)
Review
Dupuytren disease (DD) is a connective tissue disorder that consists in fibromatosis of the palmar and digital fascia (in form of nodules or flanges) that leads to the development of flexion contractures of the palm and fingers. The little and ring finger are particularly affected. The disease can limit hand function, reducing the quality of life. The disease can have a traumatic origin and is also associated with conditions such as diabetes mellitus, alcoholism, dyslipidemia, epilepsy and AIDS, among others. However, none of these conditions can fully explain the genesis of DD. A hereditary component is described in 40% of patients and is attributed to an autosomal dominant gene of variable penetrance, probably related to collagen synthesis. However there are also spontaneous and recessive inheritance cases. The diagnosis is clinical and based on physical examination. Treatment ranges from observation or use of injectable collagenase to the surgical option in cases with significant functional limitations.
Topics: Collagenases; Dupuytren Contracture; Fingers; Humans
PubMed: 23354642
DOI: 10.4067/S0034-98872012000900013 -
PloS One 2017One of the major determinants of Dupyutren disease (DD) treatment efficacy is recurrence of the contracture. Unfortunately, lack of agreement in the literature on what...
PURPOSE
One of the major determinants of Dupyutren disease (DD) treatment efficacy is recurrence of the contracture. Unfortunately, lack of agreement in the literature on what constitutes recurrence makes it nearly impossible to compare the multiple treatments alternatives available today. The aim of this study is to bring an unbiased pool of experts to agree upon what would be considered a recurrence of DD after treatment; and from that consensus establish a much-needed definition for DD recurrence.
METHODS
To reach an expert consensus on the definition of recurrence we used the Delphi method and invited 43 Dupuytren's research and treatment experts from 10 countries to participate by answering a series of questionnaire rounds. After each round the answers were analyzed and the experts received a feedback report with another questionnaire round to further hone in of the definition. We defined consensus when at least 70% of the experts agreed on a topic.
RESULTS
Twenty-one experts agreed to participate in this study. After four consensus rounds, we agreed that DD recurrence should be defined as "more than 20 degrees of contracture recurrence in any treated joint at one year post-treatment compared to six weeks post-treatment". In addition, "recurrence should be reported individually for every treated joint" and afterwards measurements should be repeated and reported yearly.
CONCLUSION
This study provides the most comprehensive to date definition of what should be considered recurrence of DD. These standardized criteria should allow us to better evaluate the many treatment alternatives.
Topics: Clinical Decision-Making; Disease Management; Dupuytren Contracture; Expert Testimony; Humans; Recurrence; Treatment Outcome
PubMed: 28505187
DOI: 10.1371/journal.pone.0164849