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Case Reports in Pediatrics 2016Empedobacter brevis is gram-negative bacilli that belongs to Flavobacteriaceae family. It was previously known with name of Flavobacterium breve. The reservoir of these...
Empedobacter brevis is gram-negative bacilli that belongs to Flavobacteriaceae family. It was previously known with name of Flavobacterium breve. The reservoir of these bacteria is soil, plants, water, food, hospital water sources, including incubators, sinks, faucets, tap water, hemodialysis systems, saline solutions, and other pharmaceutical solutions. We report a case of term female newborn, admitted with complaint of respiratory distress developing soon after birth and developed clinical features of sepsis at age of 92 hours of postnatal life. The sepsis screen was positive and blood culture and cerebrospinal fluid showed growth of Empedobacter brevis that was resistant to multiple antibiotics. The neonate was treated with appropriate antibiotics and was discharged successfully. The novelty of the case report is that this is the first case report of neonatal sepsis caused by Empedobacter brevis.
PubMed: 27648334
DOI: 10.1155/2016/7609602 -
Journal of Investigative Medicine High... 2015Introduction. In December 2014, the Food and Drug Administration issued a recall of all Wallcur simulation products due to reports of their use in clinical practice. We...
Introduction. In December 2014, the Food and Drug Administration issued a recall of all Wallcur simulation products due to reports of their use in clinical practice. We present a case of septic shock and multiorgan failure after the accidental intravenous infusion of a nonsterile Wallcur simulation product. Case. The patient presented with symptoms of rigors and dyspnea occurring immediately after infusion of Wallcur Practi-0.9% saline. Initial laboratory evidence was consistent with severe septic shock and multiorgan dysfunction. His initial lactic acid level was 9 mmol/L (reference range = 0.5-2.2), and he had evidence of acute kidney injury and markers of disseminated intravascular coagulation. All 4 blood culture bottles isolated multidrug-resistant Empedobacter brevis. The patient recovered from his illness and was discharged with ciprofloxacin therapy per susceptibilities. Discussion. This patient represents the first described case of severe septic shock associated with the infusion of a Wallcur simulation product. Intravenous inoculation of a nonsterile fluid is rare and exposes the patient to unusual environmental organisms, toxins, or unsafe fluid characteristics such as tonicity. During course of treatment, we identified the possible culprit to be a multidrug-resistant isolate of Empedobacter brevis. We also discuss the systemic failures that led to this outbreak.
PubMed: 26668812
DOI: 10.1177/2324709615618980 -
Empedobacter brevis Bacteremia in a Patient Infected with HIV: Case Report and Review of Literature.Case Reports in Infectious Diseases 2015Clinical disease caused by Empedobacter brevis (E. brevis) is very rare. We report the first case of E. brevis bacteremia in a patient with HIV and review the current...
Clinical disease caused by Empedobacter brevis (E. brevis) is very rare. We report the first case of E. brevis bacteremia in a patient with HIV and review the current literature. A 69-year-old man with human immunodeficiency virus (HIV) and CD4 count of 319 presented with chief complaints of black tarry stools, nausea and vomiting for 2 days. Physical exam was significant for abdominal pain on palpation with no rebound or guarding. His total leukocyte count was 32,000 cells/μL with 82% neutrophils and 9% bands. Emergent colonoscopy and endoscopic esophagogastroduodenoscopy showed esophageal candidiasis, a nonbleeding gastric ulcer, and diverticulosis. Blood cultures drawn on days 1, 2, and 3 of hospitalization grew E. brevis. Patient improved with intravenous antibiotics. This case is unusual, raising the possibility of gastrointestinal colonization as a source of the patient's bacteremia. In conclusion, E. brevis is an emerging pathogen that can cause serious health care associated infections.
PubMed: 26550499
DOI: 10.1155/2015/813528 -
Therapeutic Apheresis and Dialysis :... Feb 2022
Topics: Aged; Anti-Bacterial Agents; Flavobacteriaceae; Flavobacteriaceae Infections; Humans; Kidney Failure, Chronic; Male; Peritoneal Dialysis; Peritonitis
PubMed: 34272824
DOI: 10.1111/1744-9987.13709 -
Journal of Drugs in Dermatology : JDD Feb 2022Empedobacter brevis (E. brevis) is a gram-negative, nonmotile, aerobic bacteria that is part of the Flavobacteriaceae family. It is mostly found in water sources,...
Empedobacter brevis (E. brevis) is a gram-negative, nonmotile, aerobic bacteria that is part of the Flavobacteriaceae family. It is mostly found in water sources, plants, soils, and more recently, hospital environments. There have been emerging cases of human infections, although still rare.
Topics: Cellulitis; Flavobacteriaceae; Flavobacterium; Humans; Tetracyclines
PubMed: 35133115
DOI: 10.36849/jdd.6628 -
Antimicrobial Agents and Chemotherapy Sep 2019Emerging novel resistance mechanisms pose a great public health concern.….
Emerging novel resistance mechanisms pose a great public health concern.….
PubMed: 31570401
DOI: 10.1128/AAC.01636-19 -
International Journal of Systematic and... Sep 2019A Gram-stain-negative, aerobic, non-motile and ovoid or rod-shaped bacterial strain, MRS2, was isolated from an intestine of Nile tilapia () collected from the Republic...
A Gram-stain-negative, aerobic, non-motile and ovoid or rod-shaped bacterial strain, MRS2, was isolated from an intestine of Nile tilapia () collected from the Republic of Korea. Strain MRS2 grew optimally at 30 °C and in the presence of 0-2.0 % (w/v) NaCl. A neighbour-joining phylogenetic tree of 16S rRNA gene sequences showed that strain MRS2 clustered with the type strains of species. It exhibited the highest 16S rRNA gene sequence similarity (98.5 %) to the type strain of and sequence similarities of 97.4-97.6 % to the type strains of two other species. Strain MRS2 contained MK-6 as the predominant ubiquinone and summed feature 3 (Cω7 and/or Cω6), iso-C 3-OH and iso-C as the major fatty acids. The major polar lipids of strain MRS2 were phosphatidylethanolamine, one unidentified lipid and one unidentified aminolipid. The DNA G+C contents of strain MRS2 were 32.2 mol% or 30.65 mol%. Strain MRS2 exhibited DNA-DNA relatedness values of 12-20 % to the type strains of , and . The average nucleotide identity values between strain MRS2 and five strains of and were 84.8-91.0 %. The phylogenetic, genetic and differential phenotypic properties indicated that strain MRS2 is separated from species. On the basis of the data presented here, strain MRS2 is considered to represent a novel species of the genus , for which the name sp. nov. is proposed. The type strain is MRS2 (=KCTC 62904=NBRC 113550).
Topics: Animals; Bacterial Typing Techniques; Base Composition; Cichlids; DNA, Bacterial; Fatty Acids; Flavobacteriaceae; Flavobacterium; Intestines; Phosphatidylethanolamines; Phylogeny; RNA, Ribosomal, 16S; Republic of Korea; Sequence Analysis, DNA; Vitamin K 2
PubMed: 31246165
DOI: 10.1099/ijsem.0.003558 -
Graefe's Archive For Clinical and... Apr 2002We present a series of patients who were operated upon on the same day by the same surgeon. All of those patients developed postoperative endophthalmitis due to...
BACKGROUND
We present a series of patients who were operated upon on the same day by the same surgeon. All of those patients developed postoperative endophthalmitis due to Empedobacter brevis - a bacterium hitherto unknown in ophthalmologic literature.
METHODS
Twelve patients were referred because of endophthalmitis after cataract extraction. The patients' files were studied and the intraoperative and postoperative outcome was analysed.
RESULTS
Twelve patients (five male, seven female, mean age 75 years) presented 1-6 days after uncomplicated cataract extraction. Although some suffered from medical or ophthalmological diseases there was no association with the severity of the endophthalmitis. Eleven patients required vitrectomy, seven as primary procedure, one primary with extraction of the lens and three secondary after anterior chamber lavage and intravitreal antibiotics. In three cases vitrectomy had to be repeated together with extraction of the intraocular lens. There were two postoperative retinal detachments that required silicon oil and in one case an encircling band. Mean visual acuity rose from 0.02 to 0.47 by 9 months after operation. Empedobacter brevis was found in the anterior chamber and in the vitreous in all except one patient.
CONCLUSION
In high-volume cataract surgery endemic endophthalmitis is always possible. Sources of infection may be anything from the lens to the sterilisation process, the latter being the primary suspect in our series. Prompt, adequate and (if necessary) aggressive treatment by vitreous surgery may lead to favourable results.
Topics: Aged; Aged, 80 and over; Anterior Chamber; Anti-Bacterial Agents; Cataract Extraction; Combined Modality Therapy; Disease Outbreaks; Endophthalmitis; Eye Infections, Bacterial; Female; Flavobacterium; Germany; Gram-Negative Bacterial Infections; Humans; Male; Middle Aged; Postoperative Complications; Reoperation; Vitrectomy; Vitreous Body
PubMed: 11981643
DOI: 10.1007/s00417-002-0435-5 -
Journal of Global Infectious Diseases Apr 2012
PubMed: 22754253
DOI: 10.4103/0974-777X.96783 -
International Journal of Systematic and... Oct 2015Two Gram-stain-negative, rod-shaped bacteria, strains 990B6_12ER2AT and 994B6_12ER2A, were isolated during microbiological analysis of a mixed manure sample which was...
Two Gram-stain-negative, rod-shaped bacteria, strains 990B6_12ER2AT and 994B6_12ER2A, were isolated during microbiological analysis of a mixed manure sample which was used as input material for a German biogas plant. Phylogenetic identification based on nearly full-length 16S rRNA gene sequences placed the isolates into the family Flavobacteriaceae within the phylum Bacteroidetes. Strains 990B6_12ER2AT and 994B6_12ER2A shared identical 16S rRNA gene sequences and showed highest 16S rRNA gene sequence similarity to the type strains of Empedobacter falsenii (97.3 %) and Empedobacter brevis (96.8 %).The major cellular fatty acids of strains 990B6_12ER2AT and 994B6_12ER2A were iso-C15 : 0, summed feature 3 (C16 : 1ω7c and/or C16 : 1ω6c) and iso-C17 : 0 3-OH.The polyamine pattern contained predominantly sym-homospermidine and the quinone system was menaquinone MK-6. Major polar lipids were phosphatidylethanolamine, one unidentified aminolipid and one unidentified polar lipid not containing an amino residue, a phosphate residue or a sugar moiety. In addition, moderate to minor amounts of several unidentified lipids were detected. The DNA G+C content was 31.7 and 29.0 mol%, for strains 990B6_12ER2AT and 994B6_12ER2A, respectively. On the basis of phylogenetic, chemotaxonomic and physiological analysis we propose a novel species of the genus Empedobacter, Empedobacter stercoris sp. nov. (type strain 990B6_12ER2AT = CIP 110833T = LMG 28501T).
Topics: Animals; Bacterial Typing Techniques; Base Composition; Biofuels; Cattle; DNA, Bacterial; Fatty Acids; Flavobacteriaceae; Germany; Manure; Molecular Sequence Data; Phosphatidylethanolamines; Phylogeny; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Spermidine; Swine; Vitamin K 2
PubMed: 26228269
DOI: 10.1099/ijsem.0.000486