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Lancet (London, England) Nov 1959
Topics: Hypophysectomy
PubMed: 13857519
DOI: No ID Found -
Clinical Otolaryngology and Allied... May 1978
Topics: Acromegaly; Adrenal Cortex Hormones; Anesthesia; Anti-Bacterial Agents; Breast Neoplasms; History, 20th Century; Humans; Hypophysectomy; Microsurgery; Pituitary Gland; Pituitary Neoplasms; Postoperative Complications
PubMed: 352581
DOI: 10.1111/j.1365-2273.1978.tb00685.x -
Archives of Otolaryngology (Chicago,... Jul 1961
Topics: Hypophysectomy
PubMed: 13710960
DOI: 10.1001/archotol.1961.00740030005002 -
Journal of Neurosurgery Jun 2004
Topics: Breast Neoplasms; Carcinoma; History, 20th Century; Humans; Hypophysectomy; Pain; Pituitary Gland; Quality of Life; Radiosurgery; Sweden
PubMed: 15200139
DOI: 10.3171/jns.2004.100.6.1133 -
The Veterinary Quarterly Oct 1999
Review
Topics: Animals; Cushing Syndrome; Dog Diseases; Dogs; Hypophysectomy
PubMed: 10568003
DOI: 10.1080/01652176.1999.9695008 -
Journal of Neurosurgery Aug 2007
Topics: History, 20th Century; Humans; Hypophysectomy
PubMed: 17695407
DOI: 10.3171/JNS-07/08/0458 -
AORN Journal Feb 1981
Topics: Breast Neoplasms; Diabetes Insipidus; Female; Humans; Hypophysectomy; Male; Pain, Intractable; Palliative Care; Postoperative Complications; Prostatic Neoplasms
PubMed: 6162421
DOI: 10.1016/s0001-2092(07)62183-8 -
Journal of Veterinary Internal Medicine Mar 2021Successful treatment of cats with hypersomatotropism by transsphenoidal hypophysectomy is described in small numbers of cats.
BACKGROUND
Successful treatment of cats with hypersomatotropism by transsphenoidal hypophysectomy is described in small numbers of cats.
OBJECTIVES
To describe the endocrine profile, survival, and remission rates of hypersomatotropism and diabetes mellitus in a cohort of cats with hypersomatotropism that underwent hypophysectomy between 2008 and 2020.
ANIMALS
Twenty-five client-owned cats with spontaneous hypersomatotropism.
METHODS
Retrospective study. Diagnosis of hypersomatotropism was based on clinical signs, plasma insulin-like growth factor-1 (IGF-1) concentration, and imaging of the pituitary gland. Growth hormone (GH) and IGF-1 concentrations were measured repeatedly after surgery. Survival times were calculated based on follow-up information from owners and referring veterinarians.
RESULTS
Median postoperative hospital stay was 7 days (range, 3-18 days). One cat died within 4 weeks of surgery. Median plasma GH concentration decreased significantly from 51.0 ng/mL (range, 5.0-101.0 ng/mL) before surgery to 3.8 ng/mL (range, 0.6-13.0 ng/mL) at 5 hours after surgery. Remission of hypersomatotropism, defined as normalization of plasma IGF-1 concentration, occurred in 23/24 cats (median, 34 ng/mL; range, 14-240 ng/mL) and 22/24 cats entered diabetic remission. Median survival time was 1347 days (95% confidence interval, 900-1794 days; range, 11-3180 days) and the overall 1-, 2-, and 3-year all-cause survival rates were 76%, 76%, and 52%, respectively.
CONCLUSIONS AND CLINICAL IMPORTANCE
This study shows the beneficial outcome of hypophysectomy in cats with hypersomatotropism, marked by low death rate and a high percentage of diabetic remission and definitive cure.
Topics: Acromegaly; Animals; Cat Diseases; Cats; Diabetes Mellitus; Growth Hormone; Hypophysectomy; Insulin-Like Growth Factor I; Retrospective Studies
PubMed: 33621385
DOI: 10.1111/jvim.16047 -
Otolaryngologic Clinics of North America Feb 1971
Review
Topics: Humans; Hypophysectomy; Postoperative Complications; Sphenoid Sinus
PubMed: 5006515
DOI: No ID Found -
Journal of Neurosurgical Nursing Oct 1969
Topics: Craniotomy; Hypophysectomy; Nursing; Stereotaxic Techniques
PubMed: 4933812
DOI: 10.1097/01376517-196910000-00007