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The American Journal of Digestive... Sep 1977
Topics: Animals; Colchicine; DNA; Dexamethasone; Enteritis; Female; Ileum; Indomethacin; Intestinal Mucosa; Jejunum; Macromolecular Substances; Male; Prednisolone; Prostaglandins E; Prostaglandins, Synthetic; Proteins; RNA; Rats; Ulcer
PubMed: 900091
DOI: 10.1007/BF01694504 -
JAMA Jan 1967
Topics: Aged; Gluconates; Humans; Hydrochlorothiazide; Intestinal Diseases; Intestinal Obstruction; Jejunum; Potassium; Ulcer
PubMed: 6071175
DOI: 10.1001/jama.199.3.217 -
Journal of Clinical Gastroenterology Jun 1988
Topics: Humans; Jejunal Diseases; Jejunum; Male; Middle Aged; Ulcer
PubMed: 2980778
DOI: No ID Found -
Current Topics in Pathology. Ergebnisse... 1976
Review
Topics: Adult; Autopsy; Biopsy; Celiac Disease; Cell Count; Child; Humans; Intestinal Mucosa; Intestinal Neoplasms; Intestinal Obstruction; Jejunum; Lymphoma; Ulcer
PubMed: 795616
DOI: 10.1007/978-3-642-66481-6_2 -
Zentralblatt Fur Chirurgie Jul 1968
Topics: Diagnosis, Differential; Diverticulum; Female; Humans; Jejunum; Laparotomy; Middle Aged; Peptic Ulcer
PubMed: 4969943
DOI: No ID Found -
Zentralblatt Fur Chirurgie 1951
Topics: Intestinal Diseases; Jejunum; Peptic Ulcer; Ulcer
PubMed: 14902040
DOI: No ID Found -
The American Journal of Surgical... Jun 2012Since first described in the mid 1990s, there has been burgeoning literature on IgG4-related sclerosing disease. The number of sites that may be involved is ever...
Since first described in the mid 1990s, there has been burgeoning literature on IgG4-related sclerosing disease. The number of sites that may be involved is ever increasing, with the pancreas, salivary glands, and lymph nodes being the most commonly affected organs. There are no well-documented cases arising in the gastrointestinal tract. In this report, we present the first case to our knowledge of IgG4-related sclerosing disease involving the small bowel with a distinctly unusual clinicopathologic presentation. A previously well 46-year-old woman presented with a 2-year history of intermittent abdominal pain with recent worsening due to small bowel obstruction. Following imaging, which showed jejunitis with surrounding mesenteric inflammatory changes, she proceeded to a segmental small bowel resection. The resected jejunum revealed an isolated, stenosing chronic ulcer associated with a necrotizing mesenteric arteritis. A transmural inflammatory infiltrate rich in IgG4 plasma cells was seen in the wall of the bowel and mesenteric artery. Abundant IgG4 interfollicular plasma cells were also identified in a mesenteric lymph node. The serum IgG4 level was elevated at >800 mg/dL (reference range 8 to 140 mg/dL). Although phlebitis is an almost constant feature of this disease, arteritis is not described other than in the lung and aorta. In this report, we also discuss the diagnostic pitfalls and the differential diagnoses that should be considered when this condition arises in the gastrointestinal tract.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Autoimmune Diseases; Biomarkers; Chronic Disease; Diagnosis, Differential; Female; Humans; Immunoglobulin G; Intestinal Obstruction; Jejunal Diseases; Jejunum; Mesenteric Arteries; Middle Aged; Mycophenolic Acid; Plasma Cells; Polyarteritis Nodosa; Prednisolone; Sclerosis; Treatment Outcome; Ulcer
PubMed: 22367294
DOI: 10.1097/PAS.0b013e3182495c96 -
The American Journal of Gastroenterology Jul 1971
Topics: Adrenocorticotropic Hormone; Autopsy; Chronic Disease; Colon; Diarrhea; Diet Therapy; Feces; Female; Humans; Hydrocortisone; Ileitis; Ileum; Intestinal Diseases; Jejunum; Malabsorption Syndromes; Middle Aged; Prednisone; Radiography; Stomach; Ulcer
PubMed: 4327633
DOI: No ID Found -
Zhonghua Wai Ke Za Zhi [Chinese Journal... Aug 1983
Topics: Adult; Female; Humans; Jejunum; Male; Middle Aged; Peptic Ulcer; Postoperative Complications; Stomach; Ulcer
PubMed: 6653250
DOI: No ID Found -
Journal of Radiation Research Jul 2008Polaprezinc, an anti-ulcer drug, is a chelate compound consisting of zinc and L-carnosine. Polaprezinc has been shown to prevent gastric mucosal injury. The anti ulcer...
Polaprezinc, an anti-ulcer drug, is a chelate compound consisting of zinc and L-carnosine. Polaprezinc has been shown to prevent gastric mucosal injury. The anti ulcer effects of polaprezinc have been ascribed to its antioxidative property. The effect of polaprezinc on ionizing radiation-induced apoptosis was studied in the jejunal epithelial crypt cells of rats. Seven-to eight week-old Wistar rats, which were treated with 100 mg/kg of polaprezinc orally 1h before irradiation or 2% carboxymethyl cellulose sodium in controls, were exposed to whole body X-ray irradiation at 2 Gy. The number of apoptotic cells per jejunum crypt was counted in haematoxylin and eosin stained sections at 0-6 h after irradiation. TUNEL positive cells and immunopositive cells for active caspase-3 per crypt were also counted. Accumulation of p53, p21(WAF1/CIP1) and Bax expression in the jejunum after irradiation were examined by Western blot analyses. Polaprezinc treatment given prior to radiation resulted in a significant reduction in numbers of apoptotic cells, TUNEL positive cells and active caspase-3 immunopositive cells in jejunal crypt cells. Polaprezinc treatment resulted in decreases of p53 accumulation, p21(WAF1/CIP1) and Bax expression after irradiation. Polaprezinc has a protective effect against ionizing radiation induced apoptosis in rat jejunal crypt cells.
Topics: Animals; Apoptosis; Carnosine; Cells, Cultured; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Jejunum; Male; Organometallic Compounds; Radiation Dosage; Radiation-Protective Agents; Rats; Rats, Wistar; Zinc Compounds
PubMed: 18413982
DOI: 10.1269/jrr.07114