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Chirurgia (Bucharest, Romania : 1990) 2011Ulcerative ischemic lesions of the small bowel represents a rare abdominal pathology. We present the case of a 68-year-old male who was admitted to our hospital for...
Ulcerative ischemic lesions of the small bowel represents a rare abdominal pathology. We present the case of a 68-year-old male who was admitted to our hospital for abdominal pain, nausea and vomiting. Ultrasound examination followed by upper endoscopy raised up the suspicion of a jejunal ulcerative perforated lesion. Surgery confirmed the diagnosis, revealing the jejunal ulcer, perforated and blocked by the adjacent enteral loops. Ischemic etiology of the ulceration was indicated by the mesenteric thrombus. The anatomopathologic finding together with the clinical and imagistic examinations lead us to the diagnosis of thromboangiitis obliterans, cause of the mesenteric ischemia; the future problems regarding this case are the long term follow up, in order to be able to recognise the visceral ischemic recurency that might occur.
Topics: Abdominal Pain; Aged; Follow-Up Studies; Humans; Hypertension; Intestinal Perforation; Ischemia; Jejunal Diseases; Jejunum; Male; Myocardial Ischemia; Nausea; Thromboangiitis Obliterans; Treatment Outcome; Ulcer; Vomiting
PubMed: 21698866
DOI: No ID Found -
Annals of Surgery Apr 1960
Topics: Disease; Humans; Jejunum; Ulcer
PubMed: 14417590
DOI: 10.1097/00000658-196004000-00022 -
Polski Przeglad Chirurgiczny Sep 2016Non-traumatic perforation of the digestive tract occurs most often in the duodenum and stomach (peptic ulcer), as well as the colon (diverticulitis, cancer or ischemic...
Non-traumatic perforation of the digestive tract occurs most often in the duodenum and stomach (peptic ulcer), as well as the colon (diverticulitis, cancer or ischemic lesions). Perforation of the small bowel is very rare. The Authors of the study presented a case of proximal jejunum perforation, which occurred in a patient with a history of duodenal peptic ulcer disease. Diagnosis posed no difficulties, and treatment included the excision of the ulceration and suturing of the bowel. The patient recovered without complications and the histological examination failed to reveal the nature of the ulcer. However, based on the medical history, one may suppose that it might be of peptic etiology, which makes this case exceptional.
Topics: Humans; Jejunum; Male; Middle Aged; Peptic Ulcer; Poland; Treatment Outcome
PubMed: 27648623
DOI: 10.1515/pjs-2016-0054 -
Surgery Mar 1951
Topics: Gastroenterostomy; Histamine; Humans; Jejunum; Peptic Ulcer; Protective Agents; Ulcer
PubMed: 14835131
DOI: No ID Found -
Clinical Gastroenterology and... Jun 2017
Topics: Anti-Inflammatory Agents, Non-Steroidal; Endoscopy; Female; Humans; Jejunal Diseases; Middle Aged; Ulcer
PubMed: 28235573
DOI: 10.1016/j.cgh.2017.02.013 -
Journal of Pediatric Surgery Sep 2018The purpose of this study is to review published reports and contribute new cases of umbilical cord ulceration (UCU) with perinatal hemorrhage into the amniotic cavity... (Observational Study)
Observational Study
PURPOSE
The purpose of this study is to review published reports and contribute new cases of umbilical cord ulceration (UCU) with perinatal hemorrhage into the amniotic cavity in the setting of duodenal or jejunal obstruction because knowledge of this sequence is poorly disseminated and could be lifesaving.
METHODS
Published reports of UCU with hemorrhage associated with congenital duodenal or jejunal obstruction were reviewed. Chart review was conducted for the cases encountered at our institutions between January 2008 and March 2017. We noted perinatal complications, method of delivery, gestational age, birth weight, gender, number, location, and pathologic description of umbilical cord ulcers, and outcome.
RESULTS
Thirty-one reports and 7 new cases were studied. Perinatal complications included: preterm labor or preterm premature rupture of membranes: 63%; fetal distress: 95%; mean gestational age: 33weeks; premature gestation: 95%; bloody amniotic fluid: 90%. Pathological analysis of UCUs revealed solitary, multifocal, helical and punched-out lesions. There were 12 neonatal deaths (32%), and 12 intrauterine deaths (32%). Survival rate was 37%.
CONCLUSIONS
UCU with perinatal hemorrhage is associated with duodenal and jejunal obstruction. Knowing the typical clinical signs of this potential catastrophic complication could prompt lifesaving delivery.
TYPE OF STUDY
Prognostic LEVEL OF EVIDENCE: IV.
Topics: Duodenal Diseases; Female; Hemorrhage; Humans; Infant, Newborn; Intestinal Obstruction; Jejunal Diseases; Male; Pregnancy; Pregnancy Complications; Prenatal Diagnosis; Prognosis; Retrospective Studies; Ulcer; Umbilical Cord
PubMed: 29241965
DOI: 10.1016/j.jpedsurg.2017.11.045 -
Advances in Experimental Medicine and... 1991
Topics: Animals; Capsaicin; Denervation; Ethanol; Gastric Mucosa; Indomethacin; Jejunum; Male; Microscopy, Electron; Rats; Rats, Inbred Strains; Stomach; Stomach Ulcer
PubMed: 1950793
DOI: 10.1007/978-1-4899-0744-8_8 -
Clinical Science (London, England :... May 1985By use of a radiometric assay transglutaminase activity was demonstrated for the first time in human jejunal mucosa. The activity is similar to that in other tissues,...
By use of a radiometric assay transglutaminase activity was demonstrated for the first time in human jejunal mucosa. The activity is similar to that in other tissues, with a pH optimum of 9.0, an absolute requirement for Ca2+ and an apparent Km for putrescine of 0.15 mmol/l. Assay of jejunal transglutaminase activity with a variety of dietary proteins as acceptors showed high activity with gliadin, comparable with that of the standard substrate, dimethylcasein. Deamidation of the gliadin markedly reduced its acceptor activity. Collagen, ovalbumin, elastin and zein exhibited very low acceptor activities. Increased transglutaminase activity was demonstrated in jejunal biopsies from four patients with untreated coeliac disease compared with 14 control subjects and eight patients with inflammatory bowel disease. Eight patients with coeliac disease in remission, with normal levels of brush border alpha-glucosidase, showed elevated transglutaminase activities compared with those of controls. It is postulated that intestinal transglutaminase activity may be important in gliadin binding to tissues and thus in the pathogenesis of coeliac disease.
Topics: Acyltransferases; Celiac Disease; Colitis, Ulcerative; Crohn Disease; Dietary Proteins; Gliadin; Humans; Hydrogen-Ion Concentration; Jejunum; Kinetics; Plant Proteins; Substrate Specificity; Transglutaminases
PubMed: 2858282
DOI: 10.1042/cs0680573 -
Pediatric and Developmental Pathology :... 2016Apple peel deformity is a rare form of upper intestinal atresia of unknown etiology. Umbilical cord ulcers can occur secondary to reflux of gastric juice and bile as a...
Apple peel deformity is a rare form of upper intestinal atresia of unknown etiology. Umbilical cord ulcers can occur secondary to reflux of gastric juice and bile as a result of the atresia and can cause lethal intrauterine hemorrhage. The authors report 3 instances of congenital apple peel jejunal atresia with helical umbilical cord ulcers afflicting all female offspring in consecutive pregnancies in a single nonconsanguineous family. There was no hemorrhage from the cord ulcers, but all 3 pregnancies resulted in perinatal death. Although familial occurrence is known, our case series is probably the 1st from the Indian subcontinent and warrants further research into the genetic mechanisms and possible ethnic differences of congenital upper intestinal atresia. The causation of sudden fetal demise in the absence of antecedent cord hemorrhage remains elusive.
Topics: Abnormalities, Multiple; Adult; Autopsy; Biopsy; Cause of Death; Fatal Outcome; Female; Fetal Death; Genetic Predisposition to Disease; Genetic Testing; Heredity; Humans; India; Intestinal Atresia; Jejunum; Pedigree; Phenotype; Placenta; Predictive Value of Tests; Pregnancy; Prenatal Diagnosis; Risk Factors; Siblings; Ulcer; Umbilical Cord
PubMed: 26213797
DOI: 10.2350/15-04-1623-CR.1 -
Gut Oct 1975
Topics: Acids; Duodenal Ulcer; Humans; Jejunum
PubMed: 1205296
DOI: No ID Found