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International Journal of Clinical and... 2012The synchronous or metachronous development of Langerhans cell histiocytosis and non-Langerhans cell histiocytosis in the same patient is rare. To date, only seven cases... (Review)
Review
The synchronous or metachronous development of Langerhans cell histiocytosis and non-Langerhans cell histiocytosis in the same patient is rare. To date, only seven cases of xanthogranulomas developing in young patients with a history of Langerhans cell histiocytosis and systemic therapy have been reported in the literature. As of yet, the pathogenesis and the clinical significance of this phenomenon are unclear. We report the case of a 3 year old boy who developed juvenile Xanthogranulomas on the forehead and right upper eye lid 1.5 years after systemic therapy for monosystemic Langerhans cell histiocytosis of the bone and complete disease remission.
Topics: Antineoplastic Agents, Phytogenic; Child, Preschool; Eyelid Diseases; Forehead; Glucocorticoids; Histiocytosis, Langerhans-Cell; Humans; Male; Prednisone; Treatment Outcome; Vinblastine; Xanthogranuloma, Juvenile
PubMed: 22977671
DOI: No ID Found -
Archives of Dermatology Nov 1988
Topics: Biopsy; Female; Humans; Infant; Xanthogranuloma, Juvenile
PubMed: 3140735
DOI: No ID Found -
Pediatric Dermatology 2004
Topics: Child, Preschool; Female; Humans; Xanthogranuloma, Juvenile
PubMed: 15283809
DOI: 10.1111/j.0736-8046.2004.21427.x -
Pediatric Pathology & Laboratory... 1995
Topics: Humans; Infant; Male; Occipital Bone; Xanthogranuloma, Juvenile
PubMed: 8736607
DOI: 10.3109/15513819509026950 -
Dermatology Nursing Feb 2006
Topics: Age of Onset; Child, Preschool; Diagnosis, Differential; Humans; Male; Mass Screening; Nursing Assessment; Patient Education as Topic; Physical Examination; Prognosis; Remission, Spontaneous; Xanthogranuloma, Juvenile
PubMed: 16550899
DOI: No ID Found -
Archives of Dermatology Feb 1973
Topics: Female; Humans; Infant; Male; Neurofibromatosis 1; Xanthogranuloma, Juvenile
PubMed: 4631111
DOI: No ID Found -
Cutis May 1992Juvenile xanthogranuloma is a benign cutaneous growth presenting as papules or nodules. It is characterized by an intradermal collection of lipid-laden macrophages and...
Juvenile xanthogranuloma is a benign cutaneous growth presenting as papules or nodules. It is characterized by an intradermal collection of lipid-laden macrophages and varying degrees of fibroblastic proliferation. We have recently observed two patients with xanthogranulomas: one was found to have a papular type and the second patient had multiple nodular growths. We present these cases, which should be considered in the differential diagnosis of skin nodules.
Topics: Diagnosis, Differential; Humans; Infant; Male; Xanthogranuloma, Juvenile
PubMed: 1521494
DOI: No ID Found -
Journal of Ophthalmic Nursing &... 1995
Topics: Diagnosis, Differential; Female; Humans; Infant; Ophthalmoscopy; Xanthogranuloma, Juvenile
PubMed: 7616589
DOI: No ID Found -
Journal of the Indian Medical... Oct 1984
Topics: Eye Diseases; Female; Humans; Infant; Xanthogranuloma, Juvenile
PubMed: 6441825
DOI: No ID Found -
Pediatric Dermatology 2009A 2-year-old boy had hundreds of discrete, small, flat yellow to brown colored papules distributed over the face, neck, and trunk. Biopsy revealed a well-demarcated...
A 2-year-old boy had hundreds of discrete, small, flat yellow to brown colored papules distributed over the face, neck, and trunk. Biopsy revealed a well-demarcated infiltrate within the papillary dermis composed of histiocytes and some Touton giant cells and eosinophils. The cells were negative for protein S-100 and CD1a but positive for CD68 staining. No systemic lesions of juvenile xanthogranuloma were identified. Lichenoid juvenile xanthogranuloma is a very infrequent variant of juvenile xanthogranuloma.
Topics: Child, Preschool; Humans; Male; Xanthogranuloma, Juvenile
PubMed: 19419490
DOI: 10.1111/j.1525-1470.2009.00896.x