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Journal Francais D'ophtalmologie Oct 2021
Topics: Angioid Streaks; Humans; Hypertension; Hypertension, Malignant
PubMed: 34253393
DOI: 10.1016/j.jfo.2021.01.012 -
Nefrologia : Publicacion Oficial de La... 2002
Topics: Humans; Hypertension, Malignant
PubMed: 12516296
DOI: No ID Found -
Presse Medicale (Paris, France : 1983) Apr 2021Scleroderma renal crisis (SRC) is a rare but life-threatening complication of systemic sclerosis (SSc) characterized by malignant hypertension and acute kidney injury.... (Review)
Review
Scleroderma renal crisis (SRC) is a rare but life-threatening complication of systemic sclerosis (SSc) characterized by malignant hypertension and acute kidney injury. Historically, SRC was the leading cause of death in SSc. However, with the advent of angiotensin converting enzyme (ACE) inhibitors, mortality rates have decreased significantly. Nevertheless, one-year outcomes remain poor, with over 30% mortality and 25% of patients remaining dialysis-dependent. There is an urgent need to improve early recognition and treatment, and to identify novel treatments to improve outcomes of SRC. In this chapter, the clinical features, classification, pathophysiology, differential diagnosis, management and outcomes of SRC are presented. Specific issues relating to pregnancy, prophylactic ACE inhibition and management of essential hypertension are also discussed.
Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Diagnosis, Differential; Female; Humans; Hypertension, Malignant; Pregnancy; Pregnancy Complications; Renal Dialysis; Scleroderma, Systemic
PubMed: 33548376
DOI: 10.1016/j.lpm.2021.104063 -
Journal of the Tennessee Medical... Dec 1973
Topics: Humans; Hypertension, Malignant; Methods
PubMed: 4776033
DOI: No ID Found -
The Journal of the Kansas Medical... Nov 1979
Topics: Antihypertensive Agents; Humans; Hypertension, Malignant
PubMed: 533822
DOI: No ID Found -
Saudi Journal of Kidney Diseases and... Jan 2016Cocaine is one of the most commonly used illicit drugs with distribution and consumption throughout the world. Acute renal failure associated with rhabdomyolysis, direct...
Cocaine is one of the most commonly used illicit drugs with distribution and consumption throughout the world. Acute renal failure associated with rhabdomyolysis, direct vasoconstriction and hemodynamic alteration is well described in patients with cocaine intoxication. Cocaine use is associated with high blood pressure and may rarely induce malignant hypertension associated with thrombotic microangiopathy. We report the case of a patient who developed malignant hypertension associated with thrombotic microangiopathy after chronic consumption of cocaine. A kidney biopsy revealed thrombotic microangiopathy with fibrinoid necrosis of arterioles and glomerular tufts. He required dialysis sessions. Cocaine-mediated endothelial injury and platelet activation may play important pathogenetic roles in cocaine abusers who develop malignant hypertension associated with thrombotic microangiopathy. Clinicians need to be aware of this rare feature of cocaine intoxication.
Topics: Acute Kidney Injury; Adult; Biopsy; Blood Pressure; Cocaine-Related Disorders; Humans; Hypertension, Malignant; Kidney; Male; Renal Dialysis
PubMed: 26787585
DOI: 10.4103/1319-2442.174195 -
BMJ Case Reports Aug 2020
Topics: Antihypertensive Agents; Fundus Oculi; Humans; Hypertension, Malignant; Hypertensive Retinopathy; Male; Middle Aged; Ophthalmoscopy; Visual Acuity
PubMed: 32843463
DOI: 10.1136/bcr-2020-236617 -
La Revue de Medecine Interne Jun 2016Vasoconstrictors, widely prescribed in the congestive states during acute rhinitis, are responsible for many cases of drug-related iatrogenic disease. (Review)
Review
INTRODUCTION
Vasoconstrictors, widely prescribed in the congestive states during acute rhinitis, are responsible for many cases of drug-related iatrogenic disease.
CASE REPORT
We report the case of a 40-year-old man, who presented with an episode of malignant hypertensive crisis associated with life-threatening congestive heart decompensation. The patient interview revealed consumption to supra-therapeutic dosage of an association of naphazoline and prednisolone nasal sprays. The diagnostic work-up allowed to rule out disease-related causes of secondary hypertension. The drug-related disease was thus retained.
CONCLUSION
The results of the literature review showed many cases of vasoconstrictor poisoning responsible for central nervous system and cardiovascular involvement, especially in young children. This first case of heart failure related to nasal decongestant administration increases the scope of potentially serious risks of these drugs and demonstrates the outreach needs for health professionals and patients about their proper use.
Topics: Adult; Heart Failure; Humans; Hypertension, Malignant; Male; Naphazoline; Nasal Decongestants; Prednisolone; Prescription Drug Overuse
PubMed: 26526778
DOI: 10.1016/j.revmed.2015.09.010 -
The Journal of the Royal College of... Oct 1985A diagnosis of malignant hypertension was recorded for 165 patients in the national morbidity study between 1970 and 1973. Three patients with benign hypertension were...
A diagnosis of malignant hypertension was recorded for 165 patients in the national morbidity study between 1970 and 1973. Three patients with benign hypertension were selected as age- and sex-matched controls for each case. The general practitioners in the study were asked to complete a further questionnaire about the patients and 66% of the practices agreed to take part. Information about the retinal findings for the patients was requested and less than half of those in the national morbidity study proved to have a strict diagnosis of accelerated or malignant hypertension although they were originally recorded as patients with malignant hypertension. Of those patients originally classified as having benign hypertension 5% had the retinal appearance of accelerated or malignant hypertension.Patients had been diagnosed as having hypertension for a mean of more than five years prior to entry into the national morbidity study and the survival of patients with both benign and accelerated or malignant hypertension was good. Thirtyfour per cent of those with confirmed benign hypertension and 62% of those with definite accelerated or malignant hypertension died in the follow-up period which was on average 10 years from entry into the national morbidity study.The survival of patients registered with doctors who did not collaborate and of patients whose clinical details were missing was similar to the survival of patients for whom full details were provided.Blood pressure control was only fair with a mean of 172/101 mmHg for the group with benign hypertension and 177/107 mmHg for the group with accelerated or malignant hypertension. Blood pressure control was the poorest for those who died from a stroke. A high proportion (78%) of deaths in association with accelerated or malignant hypertension were from cardiovascular or renal causes.
Topics: Aged; England; Female; Follow-Up Studies; Humans; Hypertension; Hypertension, Malignant; Male; Middle Aged; Wales
PubMed: 4078797
DOI: No ID Found -
The Israel Medical Association Journal... Oct 2000
Topics: Diagnostic Errors; Humans; Hypertension, Malignant; Hypotension
PubMed: 11344746
DOI: No ID Found