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The Journal of Thoracic and... Mar 1993
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Meningocele; Middle Aged; Thoracic Diseases
PubMed: 8445940
DOI: No ID Found -
Neurosurgical Review 1995We report two cases of ventrolateral thoracic and lumbar meningoceles associated with neurofibromatosis type 1, and present a review of the literature. Thoracic and... (Review)
Review
We report two cases of ventrolateral thoracic and lumbar meningoceles associated with neurofibromatosis type 1, and present a review of the literature. Thoracic and lumbar meningoceles are rare lesions which are associated with neurofibromatosis in 60% to 85% of cases. Large meningoceles may cause pain, neurological signs, or respiratory complaints when located intrathoracically. Surgery is indicated in such cases, as well as when small meningoceles enlarge with time. The etiology of meningoceles in neurofibromatosis remains controversial. The authors postulate that ventrolateral lesions of the thoracic and lumbar spine are secondary to congenital mesodermal dysplasia and hypoplastic bone changes. MRI is the diagnostic method of choice, since it most adequately visualizes the pathological anatomy of the spinal cord, meninges, and adjacent structures in every sectional plane. CT scans are particularly useful in assessing the spinal bony changes.
Topics: Adult; Female; Humans; Laminectomy; Lumbar Vertebrae; Magnetic Resonance Imaging; Male; Meningocele; Middle Aged; Myelography; Neurofibromatosis 1; Neurologic Examination; Postoperative Complications; Spinal Neoplasms; Thoracic Vertebrae; Tomography, X-Ray Computed
PubMed: 7478016
DOI: 10.1007/BF00417670 -
Neurofibromatosis 1989We report a case of an adult male with neurofibromatosis and chronic low back pain. Evaluation revealed an anterior sacral meningocele, pulmonary tuberculosis, and later... (Review)
Review
We report a case of an adult male with neurofibromatosis and chronic low back pain. Evaluation revealed an anterior sacral meningocele, pulmonary tuberculosis, and later in the course of his illness, an osteolytic tuberculous mass in the sacrum. The patient was treated medically with a good outcome. The nature of anterior sacral meningoceles and tuberculosis spondylitis, the differential diagnoses, and relevant treatment options are discussed.
Topics: Adult; Humans; Magnetic Resonance Imaging; Male; Meningocele; Neurofibromatosis 1; Sacrum; Spondylitis; Tomography, X-Ray Computed
PubMed: 2518511
DOI: No ID Found -
Child's Nervous System : ChNS :... Nov 2013A peculiar case of intrasacral meningocele and spinal cord tethering is reported. Contents of the intrasacral meningocele and importance of CSF flow analyses with MRI...
A peculiar case of intrasacral meningocele and spinal cord tethering is reported. Contents of the intrasacral meningocele and importance of CSF flow analyses with MRI are discussed. Demonstration of CSF flow from the thecal sac to meningocele in the CSF flow MR imaging may be helpful for determining the possibility of meningocele growth. In this report, we have presented the determination of CSF flow as a new surgical indication in this type of cases.
Topics: Adolescent; Female; Humans; Laminectomy; Magnetic Resonance Imaging; Meningocele; Neurosurgical Procedures; Sacrum; Spinal Cord Diseases; Treatment Outcome
PubMed: 23686388
DOI: 10.1007/s00381-013-2141-5 -
International Journal of Pediatric... Feb 2020A case of a 31-day-old infant patient with a Tessier 0-14 deformity related to multiple midline deformities is presented. Although Transnasal endoscopic surgery is the...
A case of a 31-day-old infant patient with a Tessier 0-14 deformity related to multiple midline deformities is presented. Although Transnasal endoscopic surgery is the mainstay for the treatment of anterior and middle skull base meningoceles, there are complex cases in which a combined and multidisciplinary approach is necessary. The surgical decisions and techniques are described. To date, this is the first patient reported with Tessier 0-14 deformity treated with a combined endoscopic and external surgical approach.
Topics: Abnormalities, Multiple; Agenesis of Corpus Callosum; Cleft Lip; Craniofacial Abnormalities; Female; Humans; Infant; Meningocele
PubMed: 31706112
DOI: 10.1016/j.ijporl.2019.109764 -
The New England Journal of Medicine Jul 2015
Topics: Cervical Vertebrae; Female; Humans; Meningocele; Young Adult
PubMed: 26200992
DOI: 10.1056/NEJMicm1408098 -
American Journal of Medical Genetics.... Apr 2016Lateral meningocele syndrome (LMS), or Lehman syndrome, is a rare disorder characterized by multiple lateral spinal meningoceles, distinctive facial features, joint...
Lateral meningocele syndrome (LMS), or Lehman syndrome, is a rare disorder characterized by multiple lateral spinal meningoceles, distinctive facial features, joint hypermobility and hypotonia, along with skeletal, cardiac, and urogenital anomalies. Heterozygous NOTCH3 mutations affecting the terminal exon 33 were recently reported as causative in six families with LMS. We report a boy with LMS, the fourteenth reported case, with a de novo 80 base pair deletion in exon 33 of NOTCH3. Our patient's prenatal findings, complex cardiac anomalies, and severe feeding difficulties further expand our understanding of this rare condition.
Topics: Abnormalities, Multiple; Brain; Child, Preschool; DNA Mutational Analysis; Exons; Facies; Humans; Magnetic Resonance Imaging; Male; Meningocele; Mutation; Neuroimaging; Phenotype; Receptor, Notch3
PubMed: 26754023
DOI: 10.1002/ajmg.a.37541 -
Journal of the College of Physicians... May 2010Anterior sacral meningocele is a rare condition presenting as a lower abdominal mass. One such case was seen in a baby girl aged 2 months, who was admitted with...
Anterior sacral meningocele is a rare condition presenting as a lower abdominal mass. One such case was seen in a baby girl aged 2 months, who was admitted with abdominal distension and urinary difficulty for one week. She had a lower abdominal mass which investigated by MRI, turned out to be an anterior sacral meningocele causing her symptoms. The meningocele was excised successfully via an open abdominal approach. Postoperative recovery and follow-ups remained uneventful. Presentation, various diagnostic modalities and treatment options for an anterior sacral meningocele are briefly discussed.
Topics: Female; Humans; Infant; Meningocele; Sacrum
PubMed: 20642929
DOI: No ID Found -
Headache Jul 2017
Topics: Encephalocele; Female; Humans; Meningocele; Middle Aged; Sphenoid Sinus
PubMed: 28508543
DOI: 10.1111/head.13128 -
Neurosurgery Dec 2002Many theories have been proposed regarding potential causative factors for Chiari malformations. An unusual case is described in which regression of a congenital Chiari... (Review)
Review
OBJECTIVE AND IMPORTANCE
Many theories have been proposed regarding potential causative factors for Chiari malformations. An unusual case is described in which regression of a congenital Chiari malformation was observed after repair of a thoracic meningocele without direct surgical intervention to decompress the craniocervical junction. This supports the importance of an in utero craniospinal pressure gradient as a potential cause for congenital, but reversible, cerebellar herniation.
CLINICAL PRESENTATION
A newborn baby was observed to have a thoracic meningocele. Magnetic resonance imaging scan revealed a concomitant Chiari malformation. No neurological deficits were present at initial examination.
INTERVENTION
The patient underwent surgical closure of the thoracic meningocele and untethering of the spinal cord at the site of the dural defect. A postoperative magnetic resonance imaging scan obtained 3 months after the operation revealed complete resolution of the cerebellar herniation.
CONCLUSION
The resolution of the Chiari malformation in this child may have resulted from restoration of normal cerebrospinal fluid flow and elimination of the meningocele-related cerebrospinal fluid pressure gradient between the intracranial and intraspinal compartments.
Topics: Arnold-Chiari Malformation; Female; Humans; Infant, Newborn; Magnetic Resonance Imaging; Meningocele; Neurosurgical Procedures; Thoracic Diseases
PubMed: 12445356
DOI: No ID Found