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Teratology Dec 1975
Topics: Female; Food Contamination; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Mercury Poisoning; Methylmercury Compounds; Pregnancy
PubMed: 1198338
DOI: 10.1002/tera.1420120314 -
Tropical Doctor Jan 2020A 17-year-old boy was referred after jumping from a ladder onto the ground, crushing a medical thermometer with his right foot. Some days later, he complained of loss of...
A 17-year-old boy was referred after jumping from a ladder onto the ground, crushing a medical thermometer with his right foot. Some days later, he complained of loss of appetite and weakness. A radiograph of the affected foot demonstrated radiopaque densities. Blood and 24-h urine assays for mercury demonstrated toxic levels. Chelation therapy cured the patient dramatically.
Topics: Adolescent; Chelating Agents; Foot Injuries; Humans; Male; Mercury; Mercury Poisoning; Radiography; Thermometers; Treatment Outcome
PubMed: 31694474
DOI: 10.1177/0049475519884419 -
Anales Del Sistema Sanitario de Navarra 2003Metals are amongst the oldest toxic substances known to man. In today's industrialized world the sources of exposure to metals are ubiquitous both in the field of work... (Review)
Review
Metals are amongst the oldest toxic substances known to man. In today's industrialized world the sources of exposure to metals are ubiquitous both in the field of work and from polluted water, foodstuffs and the environment. Their toxicity is characterized by the metallic element in question, but this is modified by the type of compound, whether organic or inorganic, and its characteristics of hydrosolubility and liposolubility, which determines its toxicokinetics and thus the possibilities of it reaching its targets. The biomolecules most affected by metals are the proteins with enzymatic activity, which is why their pathology is multisystemic. The principal systems affected are the gastrointestinal, central and peripheral neurological, haematic and renal. Some metallic compounds are carcinogenic. Metals's treatment is conditioned by their chemical reactivity. They can be deactivated and eliminated by the administering of chelating agents that produce complex molecules, which are non-toxic and can be excreted. The principal chelating agents are: BAL (British Anti-Lewisite or dimercaprol) DMPS (2,3-Dimercapto-1-propanesulfonic Acid) and DMSA (meso-2,3-Dimercaptosuccinic or Succimer), EDTA, Penicilamine (b,b-dimethylcysteine) and Deferoxamine. Toxicokinetic characteristics, mechanism of action, clinical picture and treatment of some of the most relevant metals and metalloids: lead, mercury and arsenic, are considered.
Topics: Acute Disease; Arsenic Poisoning; Humans; Lead Poisoning; Mercury Poisoning; Metals
PubMed: 12813482
DOI: No ID Found -
Recenti Progressi in Medicina Apr 1983
Topics: Acrodynia; Humans; Mercury; Mercury Poisoning; Neurotic Disorders; Quadriplegia
PubMed: 6878859
DOI: No ID Found -
British Journal of Industrial Medicine Apr 1972225-228. The case history is presented of a man intoxicated by mercury during his employment as a filler of thermometers. The mean daily urinary excretion of mercury...
225-228. The case history is presented of a man intoxicated by mercury during his employment as a filler of thermometers. The mean daily urinary excretion of mercury was 661 μg for five estimations before treatment. The mean excretion was 875 μg for the first 10 days after beginning N-acetyl-D-penicillamine, 600 mg/day. This difference is not significant (P <0·1). The literature of the treatment of mercury poisoning is briefly reviewed.
Topics: Adult; Humans; Male; Mercury; Mercury Poisoning; Occupational Diseases; Penicillamine; Thermometers
PubMed: 5022002
DOI: 10.1136/oem.29.2.225 -
Rheumatology International Aug 2020Mercury is the only metal that remains in liquid form at the room temperature. It is a very toxic metal and even short-term exposure can lead to poisoning. Mercury... (Review)
Review
Mercury is the only metal that remains in liquid form at the room temperature. It is a very toxic metal and even short-term exposure can lead to poisoning. Mercury intoxication can affect many systems such as skin, cardiovascular, genitourinary, central and peripheral nervous, respiratory, and musculoskeletal system. Consequently, the diagnosis of mercury intoxication can be challenging due to its non-specific and multisystemic presentation. Herein, we report five pediatric cases with mercury intoxication from two families that were initially misdiagnosed as rheumatic disorders. We also performed a literature review about pediatric cases with mercury intoxication to investigate the clinical findings in children, the source of intoxication, and the current treatment preferences. As in our cases, reported patients were previously misdiagnosed as various infectious and/or rheumatic diseases before the diagnosis of mercury intoxication was established. A delay in diagnosis and treatment can cause serious morbidities and even mortality. We report this case series to emphasize the multisystemic presentation of mercury intoxication, and to remind and provide clues for physicians to recognize this rare toxicologic syndrome.
Topics: Adolescent; Child; Child, Preschool; Diagnostic Errors; Exanthema; Female; Humans; Hypertension; Male; Mercury Poisoning; Rheumatic Diseases; Tachycardia
PubMed: 32342181
DOI: 10.1007/s00296-020-04589-2 -
The Journal of the Association of... Sep 2019
Topics: Humans; Mercury Poisoning
PubMed: 31561695
DOI: No ID Found -
Journal of the American Academy of... Mar 1992Mercury and its compounds are toxic substances that are widely used in industry and agriculture. Mercury poisoning is an uncommon but important clinical entity that...
Mercury and its compounds are toxic substances that are widely used in industry and agriculture. Mercury poisoning is an uncommon but important clinical entity that often presents with psychiatric disturbances as a prominent part of the clinical picture. In this paper, a case of mercury poisoning in a 12-year-old girl with prominent psychiatric manifestations is presented. Relevant literature concerning the psychiatric manifestations of mercury poisoning is discussed. The importance of considering mercury poisoning, and toxic conditions in general, in the differential diagnosis of psychiatric disorders is emphasized.
Topics: Child; Diagnosis, Differential; Female; Humans; Mercury; Mercury Poisoning; Substance-Related Disorders
PubMed: 1564033
DOI: 10.1097/00004583-199203000-00019 -
European Journal of Pediatrics Mar 2011Mercury has a number of unique and fascinating properties. It is present in the environment in several forms, both organic and inorganic. Each of these forms has...
Mercury has a number of unique and fascinating properties. It is present in the environment in several forms, both organic and inorganic. Each of these forms has somewhat unique properties that differentiate them from the other forms, but all are toxic to humans in one way or the others. Mercury has been proven to be a potential source of poisoning in children as a result of the inappropriate handling of a liquid mercury. The cases of metallic mercury vapor intoxication not associated with occupational exposure may occur in school science laboratories, from mercury dust and powders, from latex paint containing a mercury-based fungicide, and from normal wear or installation of dental amalgam fillings. Another source of toxic mercury exposure can be broken thermometers, barometers, or sphygmomanometers that may occur in the home, and children are often victims of environmental exposure. In this paper, we present three members of a family who were exposed to mercury brought home from school by a family member. Since the mercury exposure was not known, the initial presentation and clinical picture suggested a misdiagnosis, a contagious infectious disease, because the onset of symptoms occurred at different times in the same family members. A subsequent change to a diagnosis of mercury intoxication and chelation therapy with meso-2,3-dimercaptosuccinic acid was started.
Topics: Adolescent; Chelation Therapy; Child; Female; Humans; Male; Mercury Poisoning; Siblings
PubMed: 20924603
DOI: 10.1007/s00431-010-1317-1 -
Journal of the American Academy of... Dec 2003Chronic mercury poisoning is becoming a health concern because of extensive pollution of water and fish, and the increasing consumption of fish in the human diet....
Chronic mercury poisoning is becoming a health concern because of extensive pollution of water and fish, and the increasing consumption of fish in the human diet. Mercury is extremely toxic to the body, especially the central nervous system, but diagnosis is difficult because of the lack of specific signs. A total of 11 patients were observed to have a nonpruritic or mildly pruritic discreet papular and papulovesicular eruption that correlated with high blood mercury levels. The mercury evidently came from increased seafood consumption. All of the patients improved when they were placed on either a seafood-free diet or chelation therapy. Physicians should suspect mercury poisoning in patients who eat a high-seafood diet who present with an asymptomatic or mildly pruritic papular or papulovesicular eruption.
Topics: Adult; Aged; Food Contamination; Humans; Mercury Poisoning; Middle Aged; Seafood; Skin
PubMed: 14639393
DOI: 10.1016/s0190-9622(03)02485-x