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Mesenchymoma of the lung (so called hamartoma): a review of 154 parenchymal and endobronchial cases.Thorax Oct 1987In a series of 154 patients (116 male and 38 female) with so called pulmonary hamartoma the peak incidence was in the sixth decade, with only three patients less than 20... (Review)
Review
In a series of 154 patients (116 male and 38 female) with so called pulmonary hamartoma the peak incidence was in the sixth decade, with only three patients less than 20 years of age. Sequential radiographs showed that in 55 patients the tumour first appeared in adult life and that in 53 it progressively increased in size. The age incidence and progressive growth leads to the conclusion that the tumour is a benign neoplasm rather than a hamartoma, consisting of various connective tissues intersected by clefts lined by respiratory epithelium. The epithelial elements are regarded as entrapped non-neoplastic inclusions and the tumour as a purely mesenchymal neoplasm: the name mesenchymoma therefore seems the most appropriate. There were two recurrences after simple enucleation, 10 and 12 years later. A total of 142 tumours were parenchymal, and only 12 were endobronchial. All lobes were affected but there was a slight preponderance in the left upper lobe. Four patients had two (synchronous) mesenchymomas. There was an associated bronchial carcinoma in 11 patients, synchronous in six and metachronous in five.
Topics: Adolescent; Aged; Female; Hamartoma; Humans; Lung Neoplasms; Male; Mesenchymoma; Middle Aged
PubMed: 3321538
DOI: 10.1136/thx.42.10.790 -
Journal of Surgical Oncology Feb 1984Although sarcoma occurring in the true retroperitoneum is not uncommon, sarcoma in the retrorectal space is unique. We report a patient with a malignant mesenchymoma, a... (Review)
Review
Although sarcoma occurring in the true retroperitoneum is not uncommon, sarcoma in the retrorectal space is unique. We report a patient with a malignant mesenchymoma, a rare soft tissue tumor, in the retrorectal space. Complete resection was accomplished through a combined Kraske's posterior and midline anterior approach. The rectum had not been invaded by the mass. Survival of patients with malignant mesenchymoma does not exceed 50% in most reports, and the role of adjuvant chemotherapy or radiation has yet to be defined. Its attendant morbidity must be weighed against an uncertain prognosis.
Topics: Adult; Humans; Male; Mesenchymoma; Methods; Neoplasm Recurrence, Local; Prognosis; Retroperitoneal Neoplasms
PubMed: 6363825
DOI: 10.1002/jso.2930250206 -
The American Journal of Surgical... Aug 1993We studied 12 cases of a rare primary bone neoplasm--fibrocartilaginous mesenchymoma--including five from the original report on this condition. The seven male and five...
We studied 12 cases of a rare primary bone neoplasm--fibrocartilaginous mesenchymoma--including five from the original report on this condition. The seven male and five female patients were 9 to 25 years old. The metaphyses of the long bones were the most common site, with the fibula accounting for a third of all cases. Histologically, the lesion contained spindle cells, bone trabeculae, and islands of cartilage. At least some of the cartilage was in the form of plates that resembled epiphyseal plates. Intralesional excision led to a high rate of recurrence, but no metastasis or death was related to the tumor. Our results indicate that the entity described by Dahlin and co-authors is histologically distinct and that its behavior does not merit the term malignant.
Topics: Adolescent; Adult; Bone Neoplasms; Cartilage; Child; Female; Follow-Up Studies; Humans; Male; Mesenchymoma; Tomography, X-Ray Computed
PubMed: 8338193
DOI: 10.1097/00000478-199308000-00008 -
Die Medizinische Welt Apr 1974
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; Diagnosis, Differential; Female; Humans; Infant; Male; Mesenchymoma; Middle Aged; Prognosis; Sex Factors; Thoracic Neoplasms
PubMed: 4832392
DOI: No ID Found -
Fibrocartilaginous mesenchymoma, a unique osseous lesion: case report with review of the literature.Skeletal Radiology Nov 2011Fibrocartilaginous mesenchymoma is a rare osseous tumor that primarily arises in the long bones of children and adolescents. This lesion can grow quickly and reach a... (Review)
Review
Fibrocartilaginous mesenchymoma is a rare osseous tumor that primarily arises in the long bones of children and adolescents. This lesion can grow quickly and reach a considerable size, despite its benign nature. It has proved challenging to diagnose and can be mistaken for a spectrum of benign and malignant bone tumors. The histological presentation of unique epiphyseal plate-like cartilage with destruction of the surrounding cortical bone and exhibition of dense fibrous stroma are important indicators for the diagnosis of fibrocartilaginous mesenchymoma. An 11-year-old boy presented with a left proximal humerus mass thought to be an aneurysmal bone cyst. The patient was lost to follow-up and came back 3 years later with massive growth of the lesion. Owing to the aggressive nature of the tumor, a left forequarter amputation was performed. Histological examination demonstrated numerous islands of cartilage with an exuberant spindle cell component characteristic of FCM. No distant metastases or local recurrences were identified at 2 years post-amputation. Because of the rapid growth of this lesion, it should be considered in the differential diagnosis of bone lesions in children and young adults.
Topics: Adolescent; Bone Neoplasms; Humans; Humerus; Male; Mesenchymoma; Radiography
PubMed: 21560005
DOI: 10.1007/s00256-011-1189-0 -
Anales Otorrinolaringologicos... 1999Mesenchymoma are growths made up for two or more mesenchyme derivatives that normally not joint in the same tumor, with the exception of the connective tissue which... (Review)
Review
Mesenchymoma are growths made up for two or more mesenchyme derivatives that normally not joint in the same tumor, with the exception of the connective tissue which appears in all tumors of mesenchymal lineage. Benign mesenchymoma is a rare tumor more frequent in extremities and peri-renal area or, very rarely in head and neck territories, being the oropharynx the most encountered sitting in the latter place. The paper reports a clinical case of benign cervical mesenchymoma of a long course, more than 20 years, and big size, asymptomatic and diagnosed through fine needle biopsy. After total removal the histological examination showed a composite growth of extended areas of fibrous tissue associated to vessels and other zones of ripe fat tissue.
Topics: Aged; Biopsy, Needle; Chronic Disease; Head and Neck Neoplasms; Humans; Male; Mesenchymoma; Neck; Tomography, X-Ray Computed
PubMed: 10568299
DOI: No ID Found -
Radiographics : a Review Publication of... Jan 2023
Topics: Humans; Mesenchymoma; Soft Tissue Neoplasms
PubMed: 36367823
DOI: 10.1148/rg.220185 -
Pediatric Pathology 1990Primary lung tumors are uncommon in children, and malignant mesenchymal tumors form only a small proportion of these. Leiomyosarcomas occur more commonly than... (Review)
Review
Primary lung tumors are uncommon in children, and malignant mesenchymal tumors form only a small proportion of these. Leiomyosarcomas occur more commonly than rhabdomyosarcomas, whereas malignant mesenchymomas are exceedingly rare. Of the total number of primary pulmonary rhabdomyosarcomas and malignant mesenchymomas of lung reported in children, 50% have occurred in association with congenital lung cysts. The relationship between abnormal morphogenesis and neoplasia is well documented in the kidney. A similar relationship may exist in the lung between cystic parenchymal maldevelopment and embryonal mesenchymal tumors. We report a 4-year-old boy with a malignant mesenchymoma of lung arising within a congenital lung cyst; one similar case has previously been reported to our knowledge.
Topics: Child, Preschool; Cysts; Humans; Immunohistochemistry; Lung; Lung Diseases; Lung Neoplasms; Male; Mesenchymoma; Radiography, Thoracic
PubMed: 2235763
DOI: 10.3109/15513819009064712 -
Journal of Cancer Research and... 2018Benign mesenchymomas, exceptionally rare tumors, composed of two or more nonepithelial mesenchymal elements are not usually found together in a tumor. We report herein a...
Benign mesenchymomas, exceptionally rare tumors, composed of two or more nonepithelial mesenchymal elements are not usually found together in a tumor. We report herein a rare case of benign mesenchymoma in the lower end of tibia in a 36-year-old female showing fibrous, fatty, and osseous elements.
Topics: Adult; Bone Neoplasms; Female; Humans; Mesenchymoma; Prognosis; Rare Diseases
PubMed: 29893345
DOI: 10.4103/0973-1482.172578 -
Hinyokika Kiyo. Acta Urologica Japonica Jan 1991This is a case report of a malignant mesenchymoma of the retroperitoneum. On December 1988, a 60-year-old man was hospitalized with complaints of painless and increasing... (Review)
Review
This is a case report of a malignant mesenchymoma of the retroperitoneum. On December 1988, a 60-year-old man was hospitalized with complaints of painless and increasing swelling in the left side of the abdomen. The tumor was resected on March 1, 1989; tumor weight was 4,780 g. Histologically, the lesion contained liposarcomatous, chondrosarcomatous, fibrohistiocytic and fibrosarcomatous components. After the tumor resection, he received chemotherapy according to the CYVADIC regimen, and he has been doing well without any evidence of recurrence or metastasis.
Topics: Humans; Magnetic Resonance Imaging; Male; Mesenchymoma; Middle Aged; Prognosis; Retroperitoneal Neoplasms; Tomography, X-Ray Computed
PubMed: 2011965
DOI: No ID Found