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Panminerva Medica Sep 2022
Topics: Humans; Metabolic Syndrome; Surveys and Questionnaires; Urologic Diseases
PubMed: 34931510
DOI: 10.23736/S0031-0808.21.04638-3 -
Clinics in Liver Disease Feb 2007Clinical and epidemiologic studies have associated non-alcoholic fatty liver with the metabolic syndrome, with insulin resistance as the pivotal pathogenic factor.... (Review)
Review
Clinical and epidemiologic studies have associated non-alcoholic fatty liver with the metabolic syndrome, with insulin resistance as the pivotal pathogenic factor. Obesity, type 2 diabetes mellitus, dyslipidemia, and hypertension contribute to risk for liver disease and to disease progression. The presence of multiple metabolic abnormalities is associated with the severity of liver disease. Patients have a high risk for cardiovascular morbidity and mortality, mediated by early atherosclerosis. This evidence has precise therapeutic implications: only a behavioral approach to lifestyle correction will address all alterations characterizing the metabolic syndrome, including metabolic liver disease.
Topics: Fatty Liver; Hepatitis; Humans; Metabolic Syndrome; Risk Factors
PubMed: 17544974
DOI: 10.1016/j.cld.2007.02.013 -
Progress in Cardiovascular Diseases 2016Metabolic syndrome (MetS), a clustering of metabolic risk factors, identifies individuals at increased risk of diabetes and cardiovascular disease (CVD). Measurement of... (Review)
Review
Metabolic syndrome (MetS), a clustering of metabolic risk factors, identifies individuals at increased risk of diabetes and cardiovascular disease (CVD). Measurement of waist circumference, high-density lipoprotein-cholesterol, triglycerides, blood pressure and fasting blood glucose are easily obtained in the clinic. At any level of low-density lipoprotein-cholesterol, presence of MetS increases the risk of adverse CVD outcomes including bothatherosclerotic CVD and atrial fibrillation. The MetS construct should focus the clinician on recommending behavioral lifestyle modification as this improves all of its components. The challenge, however, has been the lack of a standardized approach to achieve effective and sustained lifestyle modification in clinical practice. We briefly review various approaches useful to the clinician in counseling such patients. These include group lifestyle programs and emerging mobile technology. Technology alone may not be sufficient, but as an adjunct has the promise to improve low rates of behavioral change currently seen with traditional programs.
Topics: Cardiovascular Diseases; Diabetes Mellitus; Health Promotion; Healthy Lifestyle; Humans; Inventions; Metabolic Syndrome; Risk Reduction Behavior
PubMed: 27497505
DOI: 10.1016/j.pcad.2016.07.012 -
Current Opinion in Cardiology Sep 2004Metabolic syndrome affects almost a quarter of the adult American population and its incidence is rising in the rest of the world. Its treatment involves both... (Review)
Review
PURPOSE OF REVIEW
Metabolic syndrome affects almost a quarter of the adult American population and its incidence is rising in the rest of the world. Its treatment involves both pharmacologic and nonpharmacologic interventions. In this review the authors focus on foods with potential benefits for this disease.
RECENT FINDINGS
Metabolic syndrome is associated with the risk of diabetes, and thus cardiovascular disease. In recent years, many scientific studies have evaluated the role of different foods and diets in the treatment of the components of metabolic syndrome, especially atherogenic dyslipidemia.
SUMMARY
It is imperative to identify strategies that favorably impact this deadly syndrome. Here the authors review how different nutrients in food can modify metabolic syndrome, potentially altering its natural history, and related consequences. Although there is no "all-inclusive" diet yet, it seems plausible that a Mediterranean-style diet exhibits most of the desired attributes.
Topics: Humans; Hyperlipidemias; Metabolic Syndrome; Risk Factors
PubMed: 15316456
DOI: 10.1097/01.hco.0000134610.68815.05 -
Minerva Medica Jun 2006Metabolic and non metabolic cardiovascular risk factors tend to cluster in the same individual. The association of the cardiovascular risk factors is referred as... (Review)
Review
Metabolic and non metabolic cardiovascular risk factors tend to cluster in the same individual. The association of the cardiovascular risk factors is referred as metabolic syndrome (MS). This syndrome is associated with an increased risk of accelerated atherosclerosis and cardiovascular events. The cluster of cardiovascular risk factors of the MS includes: insulin resistance with or without glucose intolerance or diabetes, abdominal obesity, atherogenic dyslipidemia, elevated blood pressure, a proinflammatory and prothrombotic state. MS is one of the major issues in the management of cardiovascular disease because of its epidemic proportion and its impact on increasing risk of developing both cardiovascular disease and type 2 diabetes. The main therapeutic goal in the management of patients with the MS is to reduce risk for clinical cardiovascular events and to prevent type 2 diabetes. In particular, for individuals with established diabetes, risk factors management must be intensified to reduce their higher cardiovascular risk. Lifestyle changes have a critical role in the clinical management of the risk factors predisposing to MS, such as overweight/obesity, physical inactivity. A large body of evidence suggests the use of Metformin and Acarbose for the treatment of the syndrome as these drugs have consistently shown to reduce cardiovascular events and mortality. Most anti-hypertensive drugs have unfavorable metabolic profile while b-blockers, centrally acting agents and drugs targeting the renin angiotensin system should always be considered for the treatment of hypertension in patients with MS.
Topics: Atherosclerosis; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Life Style; Metabolic Syndrome; Risk Factors
PubMed: 16855517
DOI: No ID Found -
Diabetes Research and Clinical Practice Sep 2018Metabolic syndrome (MetS) and cancer share many modifiable risk factors including age, genetic factors, obesity, physical inactivity, unhealthy diet, alcohol, smoking,... (Review)
Review
Metabolic syndrome (MetS) and cancer share many modifiable risk factors including age, genetic factors, obesity, physical inactivity, unhealthy diet, alcohol, smoking, endocrine disruptors exposure, circadian clock disturbances, and air pollution. MetS is closely linked to cancer, as it increases cancer risk and cancer-related mortality; moreover, cancer survivors have an increased risk of MetS. Elucidating the mechanisms linking MetS to cancer is important to prevent or delay these two conditions. Possible mechanisms explaining the relationship between MetS and cancer include hyperinsulinemia and alterations of insulin-like growth factor system, chronic subclinical inflammation, abnormalities in sex hormones metabolism and adipokines, hyperglicemia, alterations in both gene expression and hormonal profile by endocrine disruptors and air pollution, desynchronization of circadian clock. The common soil hypothesis claims that MetS may be considered a surrogate marker for dietary risk factors of cancer, and a warning sign for susceptible individuals exposed to an unhealthy diet. The common soil hypothesis and the clepsydra of foods represent a theoretical substrate to preventive intervention strategies against the pandemics of MetS and cancer: adherence to healthy dietary patterns is associated with a reduced risk of MetS, and improvement of the quality of diet is consistently associated with a reduction in cancer-related mortality.
Topics: Humans; Metabolic Syndrome; Neoplasms
PubMed: 29807099
DOI: 10.1016/j.diabres.2018.05.024 -
BMJ (Clinical Research Ed.) Nov 2005
Topics: Cardiovascular Diseases; Early Diagnosis; Humans; Metabolic Syndrome; Risk Factors
PubMed: 16293811
DOI: 10.1136/bmj.331.7526.1153 -
Journal of Continuing Education in... 2006
Review
Topics: Coronary Disease; Diabetes Mellitus, Type 1; Exercise; Feeding Behavior; Humans; Life Style; Metabolic Syndrome; Nurse's Role; Patient Care Team; Prevalence; Risk Factors; United States
PubMed: 16892664
DOI: 10.3928/00220124-20060701-06 -
Arquivos Brasileiros de Cardiologia Apr 2012Metabolic syndrome has been proposed as a predictor of cardiovascular risk. However, such idea lacks strong scientific basis. This article reviews the evidence regarding... (Review)
Review
Metabolic syndrome has been proposed as a predictor of cardiovascular risk. However, such idea lacks strong scientific basis. This article reviews the evidence regarding that issue, challenging the existing paradigm of the prognostic value of metabolic syndrome.
Topics: Humans; Metabolic Syndrome; Predictive Value of Tests; Risk Assessment
PubMed: 22735916
DOI: 10.1590/s0066-782x2012000400016 -
Pediatrics in Review May 2016
Review
Topics: Adolescent; Child; Humans; Metabolic Syndrome
PubMed: 27139327
DOI: 10.1542/pir.2014-0095