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Archives of Razi Institute Aug 2022Mineral oil as a barrier can minimize temperature, osmolality, and pH fluctuation of the media in the embryo production system (IVP). Regardless of these advantages,... (Review)
Review
Mineral oil as a barrier can minimize temperature, osmolality, and pH fluctuation of the media in the embryo production system (IVP). Regardless of these advantages, mineral oil quality is varied and may deteriorate during storage or transport conditions. So, it can affect the IVP outcome by absorbing the essentials factors or realizing the toxic components into the media. Although, some methods have already been developed to reduce these side effects, still there is a big concern about the safety and use of mineral oil in the IVP system. In this review, we provided an overview of the advantages and disadvantages of using mineral oil in the IVP system. We also reviewed available methods for its quality control and finally, we introduced some methods for reducing the side effects of mineral oil.
Topics: Animals; Mineral Oil; Temperature
PubMed: 36883153
DOI: 10.22092/ARI.2022.358955.2343 -
Food Additives & Contaminants. Part A,... Sep 2018Work on mineral oil hydrocarbons (MOH) contaminating food is reviewed up to about 2010, when the subject received broad publicity. It covers the period of the main... (Review)
Review
Work on mineral oil hydrocarbons (MOH) contaminating food is reviewed up to about 2010, when the subject received broad publicity. It covers the period of the main discoveries and elimination or reduction of the dominant sources: release agents used in industrial bakeries, spraying of rice, additions to animal feed, contamination of edible oils from various sources and migration from paperboard packaging. In most cases, highly refined ('white') oils were involved, but also technical oils, e.g. from the environment, and more or less crude oil fractions from jute and sisal bags. There were numerous unexpected sources, and there might still be more of those. The exposure of the consumers to MOH must have been markedly reduced in the meantime. Environmental influx may have become dominant, particularly when taking into account that these MOH go through several degradation processes which might enrich the species resisting metabolic elimination. Major gaps are in the systematic investigation of sources and the largely unavoidable levels from environmental contamination, but also in the toxicological evaluation of the various types of hydrocarbons. A regulation is overdue that avoids the present discrepancy between the low tolerance to MOH perceived as contaminants and the very high legal limits for some applications - the MOH are largely the same.
Topics: Animals; Food Contamination; Humans; Hydrocarbons; Mineral Oil
PubMed: 29894283
DOI: 10.1080/19440049.2018.1488185 -
Journal of Separation Science Jan 2021The occurrence of mineral oil in food is known since the early 1990s, and it was discovered by chance in one of the first applications using the hyphenated LC-GC system.... (Review)
Review
The occurrence of mineral oil in food is known since the early 1990s, and it was discovered by chance in one of the first applications using the hyphenated LC-GC system. Since then, the relationship between hyphenated techniques and mineral oil analysis has been tightly interrelated and successful. This review aims to show and explain how this mutual interaction has driven the development of the hyphenated techniques on one side and has supported the increase of knowledge on the other, supporting the complex task of mineral oil determination in food. The paper presents the background of the mineral oil problem in food (a brief history of its finding, toxicology, and occurrence), moving then toward the analytical determination. The development of different hyphenated techniques in relation to mineral oil determination is discussed, focusing mainly on 2D techniques, such as LC-GC. The necessity of additional dimensions, such as LC-LC-GC and comprehensive approaches, such as GC × GC and LC × GC, is also discussed. Finally, the role of the hyphenation with MS is presented.
Topics: Chromatography, Gas; Chromatography, Liquid; Food Analysis; Food Contamination; Food Packaging; Mineral Oil
PubMed: 33111479
DOI: 10.1002/jssc.202000901 -
Clinical Rheumatology Jun 2018Autoimmune/inflammatory syndrome induced by adjuvant (ASIA) includes the following conditions: siliconosis, Gulf War syndrome, macrophagic myofasciitis syndrome, and... (Review)
Review
Autoimmune/inflammatory syndrome induced by adjuvant (ASIA) includes the following conditions: siliconosis, Gulf War syndrome, macrophagic myofasciitis syndrome, and post-vaccination phenomena. Afterward, other syndromes have been recognized, such as in ASIA by mineral oil (ASIA-MO). These conditions are triggered by adjuvants and they are the result of the interplay of genetic and environmental factors. ASIA-MO is defined as the infiltration of oily type modeling substances for cosmetic purposes. It has been reported in many countries and used surreptitiously. Pathogenesis of ASIA-MO is not clear, but is characterized by chronic granulomatous inflammation, like the pristane model in mice, with increase of proinflammatory cytokines: type I interferons (IFNα and IFNß), systemic lupus erythematosus (SLE), and erosive arthritis. In humans, an increase of interleukin 1 (IL-1) has been found. Clinical spectrum of ASIA-MO is heterogeneous, varying from mild to severe and being local and systemic. The systemic manifestations can be non-specific and specific, meeting criteria for any autoimmune disease (AID), i.e., SLE, rheumatoid arthritis, and systemic sclerosis, among others. The areas of the body where the mineral oil is mostly applied include the following: buttocks (38-72%), breasts (12-16%), lower extremities (18-22%), and face (6-10%). The penis augmentation is also common. Treatment is focused on local and systemic manifestations and requires medical and surgical management representing a challenge for the physician.
Topics: Animals; Autoimmune Diseases; Cosmetic Techniques; Humans; Mineral Oil
PubMed: 29619588
DOI: 10.1007/s10067-018-4078-2 -
Journal of Chromatography. A Apr 2021The determination of the level of mineral oil contamination in foods is a well-known problem. This class of contaminants is generally divided into mineral oil saturated...
The determination of the level of mineral oil contamination in foods is a well-known problem. This class of contaminants is generally divided into mineral oil saturated and aromatic hydrocarbons with different toxicological relevance and analytical challenges. Among the many challenges, data interpretation and integration represent an important source of uncertainty in the results provided by different laboratories leading to a variation evaluated on the order of 20%. The use of multidimensional comprehensive gas chromatography (GC × GC) has been proposed to support the data interpretation but the integration and the reliability of the results using this methodology has never been systematically evaluated. The aim of this work was to assess the integration and quantification performance of a two-dimensional (2D) software. The data were generated using a novel, completely automated platform, namely LC-GC × GC coupled to dual detectors, i.e., time-of-flight mass spectrometer (MS) and flame ionization detector (FID). From a systematic study of the failures of the two-dimensional quantification approach a novel solution was proposed for simplifying and automating the entire process. The novel algorithm was tested on ad hoc created samples (i.e. a paraffin mixture added of n-alkanes) and real-world samples proving the agreement of the results obtained by LC-GC × GC and the traditional mono-dimensional approach. Moreover, the benefits of using an entirely integrated platform were emphasized, particularly regarding the identity confirmation capability of the MS data, which can be easily translated into the 2D FID quantification feature.
Topics: Alkanes; Chromatography, Gas; Chromatography, Liquid; Flame Ionization; Hydrocarbons, Aromatic; Mass Spectrometry; Mineral Oil; Reproducibility of Results
PubMed: 33744654
DOI: 10.1016/j.chroma.2021.462044 -
Nutrition Reviews Feb 1967
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Toxicology and Industrial Health May 2022Exposure to aerosols has been found to be linked to respiratory impairment. Although the effects of both indoor and outdoor exposures to particulates have been...
Exposure to aerosols has been found to be linked to respiratory impairment. Although the effects of both indoor and outdoor exposures to particulates have been extensively reported, exposures to mists are less studied. Herein, we reported a survey of mineral oil mist toxicity in an occupational exposure scenario. For the purpose of this study, 65 lathe workers of the metal processing industry, as mineral oil mist-exposed population, were studied. Thereafter, the participants' age, smoking habits and work experience were matched with those of the control workers ( = 65) who were not occupationally exposed to mist. Thereafter, air samples were evaluated from the breathing zone of the workers using NIOSH method 5026. Plasma Interleukin-1β as a pro-inflammatory indicator was assessed in all the studied subjects. Mean ± standard deviation of mineral oil mist time-weighted average exposure in lathe workers was 7.10± 3.49 mg/m3. IL-1β cytokine levels were significantly higher in the lathe groups compared to the control group. The mean level of Interleukin-1β in the control subjects (2922 pg/L) was selected as the cut-off point of the inflammation effect. Based on this pro-inflammatory point, the results of monitoring showed that 60% of the exposed were affected. A Spearman correlation was also found between mineral oil mist exposure and inflammation in the affected subjects. Our findings highlighted the immunological potential of mineral oil mist in occupational exposure. Overall, the results of this study suggested that Interleukin-1β evaluation in mineral oil mist exposure could be considered as both an acute and chronic inflammation marker.
Topics: Air Pollutants, Occupational; Humans; Inflammation; Interleukin-1beta; Mineral Oil; Occupational Exposure
PubMed: 35465785
DOI: 10.1177/07482337221090708 -
Community Practitioner : the Journal of... Feb 2011
Review
Topics: Community Health Nursing; Evidence-Based Practice; Fatty Acids, Nonesterified; Humans; Infant; Infant Care; Massage; Mineral Oil; Oleic Acid; Olive Oil; Plant Oils; Safety; Skin Care; Triglycerides
PubMed: 21388045
DOI: No ID Found -
International Journal of Cosmetic... Dec 2012This review was initially prepared in 2011 before Professor Johann Wiechers tragically passed away. It has been updated and is being published in his memory. It... (Review)
Review
This review was initially prepared in 2011 before Professor Johann Wiechers tragically passed away. It has been updated and is being published in his memory. It discusses the importance of mineral oil and its benefits to skin. Its source, structure, properties and efficacy are discussed. Mineral oil has been shown to improve skin softness and barrier function better than some other emollients using the gas-bearing dynamometer and standard water vapour transmission testing as well as in vivo studies showing its effects on suppressing transepidermal water loss (TEWL). It has also been subjected to the rigour of the newer in vivo confocal microscopic measurements now used for testing the performance of moisturizers by following the swelling characteristics of the stratum corneum and been found favourable compared with many vegetable oils. Its introduction as a cosmetic oil was in the late 1800s, and still today, it is used as one of the main components of moisturizers, a true testament to its cost to efficacy window. Naturally, it has physical effects on the stratum corneum, but it is expected that these will translate into biological effects simply through its mechanism of hydrating and occluding the stratum corneum from which many benefits are derived.
Topics: Humans; Mineral Oil; Neoplasms, Radiation-Induced; Skin; Ultraviolet Rays
PubMed: 22994201
DOI: 10.1111/j.1468-2494.2012.00752.x -
Food and Chemical Toxicology : An... Jan 2022Oral exposure to mineral oil may result in a narrow fraction of mineral oil saturated hydrocarbon (MOSH) being retained in tissues. Excess of MOSH hepatic retention may...
Oral exposure to mineral oil may result in a narrow fraction of mineral oil saturated hydrocarbon (MOSH) being retained in tissues. Excess of MOSH hepatic retention may lead to the formation of lipogranuloma caused by predominantly multiring cycloalkanes (naphthenics) in a critical range of C-C. Although hepatic lipogranuloma is of low pathological concern, MOSH tissue deposition could be minimized by using an oil of similar quality but devoid of naphthenic structures to decrease hepatic retention. Synthetic Gas to liquid (GTL) oils offer an alternative to petroleum derived mineral oils, because they do not contain naphthenic structures. To demonstrate this point, SD rats were fed either GTL oil (99% iso-alkanes) or naphthenic mineral oil (84% cycloalkanes) at 200 mg/kg bw/day for 90 or 134 days with a recovery group. Liver, fat and mesenteric lymph nodes were analyzed for alkane sub-type levels using Online-HPLC-GC-FID and GCxGC-TOF-MS. Results indicate that at equal external dose, GTL hydrocarbons result in lower tissue levels and more rapid excretion than MOSH. GTL retained hepatic fractions were also qualitatively different than MOSH constituents. Because chemical composition differences, GTL oil show low absorption and tissue retention potential and thus an advantageous alternative to conventional mineral oil.
Topics: Animals; Cycloparaffins; Female; Liver; Lymph Nodes; Mineral Oil; Oils; Paraffin; Rats; Rats, Sprague-Dawley; Tissue Distribution
PubMed: 34838897
DOI: 10.1016/j.fct.2021.112701