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Neurology India 2023
Topics: Humans; Mononeuropathies; Peripheral Nervous System Diseases; Hypertrophy
PubMed: 37322789
DOI: 10.4103/0028-3886.378702 -
Journal of Clinical Neuromuscular... Sep 2023Peripheral nerve injuries are being increasingly recognized in patients recovering from severe SARS-CoV-2 infections. Axonal neuropathies can occur, leading to lasting... (Review)
Review
INTRODUCTION
Peripheral nerve injuries are being increasingly recognized in patients recovering from severe SARS-CoV-2 infections. Axonal neuropathies can occur, leading to lasting and disabling deficits.
CASE REPORTS
We present the cases of 3 patients who developed weakness and sensory symptoms after severe SARS-CoV-2 pneumonia. The clinical deficits revealed various patterns of injury including a mononeuropathy multiplex (MNM) in the first patient, a brachial plexopathy with superimposed MNM in the second patient, and a mononeuropathy superimposed on a polyneuropathy in the third patient. Electrodiagnostic studies revealed axonopathies. The patients with MNM were left with severe disability. The third patient returned to his baseline level of functioning.
CONCLUSIONS
Severe SARS-CoV-2 infections can result in disabling axonopathies. Possible explanations include ischemic nerve damage from the profound inflammatory response and traumatic nerve injuries in the ICU setting. Preventing severe disease through vaccination and antivirals may therefore help reduce neurologic morbidity.
Topics: Humans; COVID-19; SARS-CoV-2; Mononeuropathies; Brachial Plexus Neuropathies; Polyneuropathies
PubMed: 37611267
DOI: 10.1097/CND.0000000000000450 -
Muscle & Nerve Aug 2022
Topics: Humans; Nerve Compression Syndromes; Radial Nerve; Radial Neuropathy
PubMed: 35621077
DOI: 10.1002/mus.27646 -
MMW Fortschritte Der Medizin Apr 2020
Review
Topics: Diabetes Mellitus, Type 2; Diabetic Neuropathies; Humans; Mononeuropathies; Skull
PubMed: 32342371
DOI: 10.1007/s15006-020-0429-4 -
Physical Medicine and Rehabilitation... Nov 2018Making the correct carpal tunnel syndrome diagnosis is the most important step in treatment. Electrodiagnosis can confirm carpal tunnel syndrome and eliminate mimicking... (Review)
Review
Making the correct carpal tunnel syndrome diagnosis is the most important step in treatment. Electrodiagnosis can confirm carpal tunnel syndrome and eliminate mimicking diseases from the differential. Treatment should provide satisfactory pain relief and protection of the median nerve from further deterioration. Electrodiagnosis testing provides information on focal median mononeuropathy at the wrist that could be used to classify carpal tunnel syndrome from mild to severe. The information obtained can help patients to understand and choose treatment in a patient-centered fashion. False positives can cause more harm than false negatives in the case of carpal tunnel syndrome.
Topics: Carpal Tunnel Syndrome; Electrodiagnosis; Humans
PubMed: 30293628
DOI: 10.1016/j.pmr.2018.06.009 -
Neurosurgical Focus Jun 2007Hypertrophic localized mononeuropathy is a condition that comes to clinical attention as a painless focal swelling of a peripheral nerve in an arm or leg and is... (Review)
Review
Hypertrophic localized mononeuropathy is a condition that comes to clinical attention as a painless focal swelling of a peripheral nerve in an arm or leg and is associated with a slow but progressive loss of motor and sensory function. Whether the proliferation of perineurial cells is neoplastic or degenerative--an ongoing controversy among nerve pathologists--for some patients resection of the involved portion of a nerve with autologous interposition grafting results in better functional outcome than allowing disease to follow its natural course. Patients with a painless focal enlargement of a nerve associated with progressive weakness and/or sensory loss may benefit from surgery for resection and grafting.
Topics: Humans; Hypertrophy; Mononeuropathies; Peripheral Nerves
PubMed: 17613215
DOI: 10.3171/foc.2007.22.6.24 -
Journal of Clinical Neuromuscular... Sep 2021COVID-19 is a novel coronavirus that emerged in 2019 and is responsible for a global pandemic. Numerous neurologic manifestations have been described in the literature...
OBJECTIVES
COVID-19 is a novel coronavirus that emerged in 2019 and is responsible for a global pandemic. Numerous neurologic manifestations have been described in the literature regarding COVID-19, but most studies are focused on the central nervous system. The authors have noted an association between prior COVID-19 infection and the development of a systemic neuropathy that manifests with asymmetric sensorimotor loss in the peripheral nervous system. We describe 4 cases of mononeuropathy multiplex that were diagnosed after COVID-19 infection.
METHODS
All patients included were treated for severe COVID-19 infection at New York Presbyterian Hospital and subsequently referred to the Columbia Peripheral Neuropathy Center for persistent neuropathy.
RESULTS
Patient history, COVID-19 disease course, and mononeuropathy multiplex diagnostic evaluation of the 4 patients are recounted.
CONCLUSIONS
We postulate a connection between COVID-19 and the development of mononeuropathy multiplex with implications in prognostication, rehabilitation strategies, and future treatments.
Topics: Aged; COVID-19; Diabetes Mellitus, Type 2; Electrodiagnosis; Electromyography; Female; Humans; Hypertension; Male; Middle Aged; Mononeuropathies; Neural Conduction; Neurologic Examination; Respiratory Distress Syndrome; Retrospective Studies
PubMed: 34431798
DOI: 10.1097/CND.0000000000000367 -
Nihon Rinsho. Japanese Journal of... Jun 2005
Review
Topics: Carpal Tunnel Syndrome; Cranial Nerve Diseases; Diabetic Neuropathies; Humans
PubMed: 15999771
DOI: No ID Found -
Military Medicine Aug 2021Although there is increasing awareness of brachial plexopathy secondary to rucksack use, isolated mononeuropathies have been less well described. Three cases of...
Although there is increasing awareness of brachial plexopathy secondary to rucksack use, isolated mononeuropathies have been less well described. Three cases of mononeuropathy secondary to rucksack use in military personnel are presented, including injuries to the long thoracic and spinal accessory nerves. We also review several different factors in the proper construction, components, and fitting of the rucksack that should be considered in order to prevent rucksack palsy and provide a concise suggestion for rucksack use and education.
Topics: Brachial Plexus; Brachial Plexus Neuropathies; Humans; Military Personnel; Mononeuropathies; Paralysis
PubMed: 33231605
DOI: 10.1093/milmed/usaa232 -
The Neurologist Jan 2010Saphenous mononeuropathy has been a well recognized consequence of lower extremity surgery. However, this complication has not been previously described with popliteal... (Review)
Review
INTRODUCTION
Saphenous mononeuropathy has been a well recognized consequence of lower extremity surgery. However, this complication has not been previously described with popliteal vein aneurysm repair.
CASE PRESENTATION
We report the case of a 42-year-old woman with a saphenous mononeuropathy after popliteal vein aneurysm repair. Her saphenous neuropathy was confirmed by nerve conduction studies. Her case gives us an opportunity to review saphenous mononeuropathy and its many different etiologies. We also review the role of electrodiagnostic studies in the diagnosis of saphenous mononeuropathy.
CONCLUSIONS
Though this particular iatrogenic injury has not previously been described, both neurologists and surgeons should be aware of this complication following popliteal vein aneurysm resection with saphenous vein interposition.
Topics: Adult; Aneurysm; Electrodiagnosis; Female; Humans; Mononeuropathies; Neural Conduction; Popliteal Vein; Postoperative Complications
PubMed: 20065798
DOI: 10.1097/NRL.0b013e31819f9588