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Joint Bone Spine Nov 2022
Topics: Humans; Multimodal Imaging; Positron-Emission Tomography; Muscles; Muscle Neoplasms; Muscle, Skeletal
PubMed: 35905836
DOI: 10.1016/j.jbspin.2022.105442 -
Transplant Infectious Disease : An... Feb 2022
Topics: Epstein-Barr Virus Infections; Herpesvirus 4, Human; Humans; Kidney Transplantation; Muscle Neoplasms; Smooth Muscle Tumor
PubMed: 34724310
DOI: 10.1111/tid.13756 -
Surgical Pathology Clinics Mar 2024Inflammatory rhabdomyoblastic tumor is a recently introduced name for neoplasms currently included in the World Health Organization classification of soft tissue tumors... (Review)
Review
Inflammatory rhabdomyoblastic tumor is a recently introduced name for neoplasms currently included in the World Health Organization classification of soft tissue tumors under the rubric inflammatory leiomyosarcoma. Inflammatory rhabdomyoblastic tumor is an excellent example of how surgical pathologists working in conjunction with tumor biologists can greatly improve tumor classification to the benefit of patients. Over the last 28 years, understanding of this entity has undergone a fascinating evolution. This review serves as a summary of the latest findings in inflammatory rhabdomyoblastic tumor research and a diagnostic manual for the practicing surgical pathologist.
Topics: Humans; Muscle Neoplasms; Leiomyosarcoma; Soft Tissue Neoplasms; Smooth Muscle Tumor; Muscle, Skeletal
PubMed: 38278608
DOI: 10.1016/j.path.2023.06.008 -
The Canadian Journal of Urology Aug 2022We present the case of a 73-year-old male patient who presented with obstructive urinary symptoms, pelvic pressure, and hematuria. CT imaging revealed a heterogenous...
We present the case of a 73-year-old male patient who presented with obstructive urinary symptoms, pelvic pressure, and hematuria. CT imaging revealed a heterogenous prostate enlargement, and MRI demonstrated the mass to be arising from the seminal vesicle. Prostate biopsies showed benign tissue. Surgical excision was completed and pathology revealed it to be an epithelioid smooth muscle neoplasm of uncertain biologic potential. This is only the second known case of such a seminal vesicle tumour. As soft tissue sarcomas of the seminal vesicle emerge in the literature, we may develop a better understanding of their biologic behaviour and prognostic potential.
Topics: Aged; Biological Products; Genital Neoplasms, Male; Humans; Male; Muscle Neoplasms; Pelvic Neoplasms; Prostate; Seminal Vesicles
PubMed: 35969732
DOI: No ID Found -
Clinical & Translational Oncology :... Feb 2011Metastatic carcinoma of the soft tissue is extremely rare compared with bone metastases. An intramuscular mass is often thought to be a primary soft tissue sarcoma... (Review)
Review
Metastatic carcinoma of the soft tissue is extremely rare compared with bone metastases. An intramuscular mass is often thought to be a primary soft tissue sarcoma because intramuscular metastases are very uncommon. Any painful soft tissue mass occurring in patients with a known history of carcinoma, particularly with extensive peritumoral enhancement associated with central necrosis, is highly suspicious for skeletal muscle metastasis. A needle biopsy is necessary for proper diagnosis. It is very important to make a differential diagnosis between metastasis and primary cancer in these cases. Here we present a review of known evidence.
Topics: Adult; Aged; Aged, 80 and over; Biopsy, Fine-Needle; Carcinoma; Diagnosis, Differential; Female; Humans; Incidence; Male; Middle Aged; Muscle Neoplasms; Neoplasms, Unknown Primary
PubMed: 21324797
DOI: 10.1007/s12094-011-0625-x -
JBJS Reviews Jul 2020* Bones are a common site for metastases; however, muscle metastases recently have been more commonly reported, not only as a result of the multidisciplinary approach in... (Review)
Review
* Bones are a common site for metastases; however, muscle metastases recently have been more commonly reported, not only as a result of the multidisciplinary approach in the treatment of these patients but also because of more sensitive imaging modalities such as positron emission tomography-computed tomography (PET-CT) that identify these lesions in early stages.* The most common carcinoma is lung carcinoma, with a hematogenous route of spread mainly to the axial region of the body (the psoas muscle, the gluteal muscles, and the paravertebral muscles). * Clinically, skeletal muscle metastases from carcinomas frequently present as painful palpable masses with or without swelling and are commonly found before diagnosis of the primary carcinoma.* Multiple imaging modalities, including radiographs, CT, magnetic resonance imaging (MRI), and PET-CT, have been used for diagnosis and staging, but tissue sampling is needed for a final diagnosis. The most important differential diagnosis of skeletal muscle metastases is with soft-tissue sarcomas.* Treatment is mainly based on chemotherapy and/or radiation; surgery is performed in cases of symptomatic lesions that fail to respond to nonoperative treatment.
Topics: Carcinoma; Humans; Muscle Neoplasms
PubMed: 32618741
DOI: 10.2106/JBJS.RVW.19.00114 -
RoFo : Fortschritte Auf Dem Gebiete Der... Jul 2019
Topics: Aged; Antineoplastic Agents; Breast Neoplasms; Combined Modality Therapy; Female; Humans; Magnetic Resonance Imaging; Mastectomy; Muscle Neoplasms; Muscle, Skeletal; Neoplasm Recurrence, Local; Neoplasm Staging; Nerve Compression Syndromes; Oculomotor Muscles; Optic Nerve; Tomography, X-Ray Computed
PubMed: 30665252
DOI: 10.1055/a-0820-5711 -
American Society of Clinical Oncology... 2016Treatment of muscle-invasive bladder cancer in older patients is challenging. Definitive therapy of localized disease requires either surgery or radiation therapy,... (Review)
Review
Treatment of muscle-invasive bladder cancer in older patients is challenging. Definitive therapy of localized disease requires either surgery or radiation therapy, ideally combined with systemic chemotherapy. However, current population data suggest that less than half of patients older than age 70 are offered such treatments. We will review tools available to assess the fitness of older patients for surgery, alternatives, and tips for perioperative patient treatment.
Topics: Age Factors; Aged; Aged, 80 and over; Combined Modality Therapy; Humans; Muscle Neoplasms; Neoplasm Invasiveness; Urinary Bladder Neoplasms
PubMed: 27249728
DOI: 10.1200/EDBK_158974 -
Current Oncology Reports Jun 2018Here, we will review and summarize the current status and emerging data supporting the use of trimodality therapy as an alternative to cystectomy for patients with... (Review)
Review
PURPOSE OF REVIEW
Here, we will review and summarize the current status and emerging data supporting the use of trimodality therapy as an alternative to cystectomy for patients with muscle-invasive bladder cancer.
RECENT FINDINGS
There are no randomized-controlled data comparing radical cystectomy with bladder preserving trimodality therapy available for comparison. However, observational data suggests acceptable bladder preservation and functional outcomes in patients receiving bladder preserving trimodality therapy as well as similar oncologic outcomes in select patients compared to radical cystectomy. Future trials are focusing on new techniques and novel therapeutics in patients with bladder cancer. Bladder preserving trimodality therapy results in satisfactory quality of life and comparable disease outcomes for select patients with muscle-invasive urothelial carcinoma of the bladder compared to cystectomy.
Topics: Combined Modality Therapy; Humans; Muscle Neoplasms; Neoplasm Invasiveness; Organ Sparing Treatments; Prognosis; Urinary Bladder Neoplasms
PubMed: 29959582
DOI: 10.1007/s11912-018-0711-0 -
Surgical Oncology Jun 2018Mucinous appendiceal neoplasms have a pattern of metastases that is different from the other gastrointestinal cancers. The first site for cancer dissemination is the...
BACKGROUND
Mucinous appendiceal neoplasms have a pattern of metastases that is different from the other gastrointestinal cancers. The first site for cancer dissemination is the peritoneal space surrounding the primary tumor and this is followed by increasingly extensive peritoneal spread. Invasion of the psoas and iliacus muscle is an unusual phenomenon.
METHOD
From a prospective database of appendiceal mucinous neoplasms treated by cytoreductive surgery (CRS) and perioperative hyperthermic chemotherapy (HIPEC), patients with psoas muscle invasion were reviewed. Their clinical features and treatments were tabulated.
RESULTS
Three patients with ages 33, 60, and 63 were identified. Two patients had disease progression into the psoas muscle 33 and 95 months after CRS plus HIPEC. One had dissecting mucinous tumor into psoas, iliacus and quadratus lumborum muscle at the time of diagnosis of the appendiceal mucinous neoplasm. All three survived at least five years from their initial treatment.
CONCLUSION
Despite the fact that mucinous tumor invasion was outside the peritoneal cavity, long term benefit from psoas muscle resection with a mucinous appendiceal neoplasm is possible and resection possibly with HIPEC should be considered.
Topics: Abdominal Muscles; Adenocarcinoma, Mucinous; Adult; Appendiceal Neoplasms; Biomarkers, Tumor; Chemotherapy, Adjuvant; Chemotherapy, Cancer, Regional Perfusion; Combined Modality Therapy; Cytoreduction Surgical Procedures; Female; Humans; Hyperthermia, Induced; Male; Middle Aged; Muscle Neoplasms; Peritoneal Neoplasms; Prognosis; Prospective Studies; Psoas Muscles; Tomography, X-Ray Computed
PubMed: 29937165
DOI: 10.1016/j.suronc.2018.02.002