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Lancet (London, England) Jul 1982
Topics: Humans; Immunosuppressive Agents; Myasthenia Gravis; Neostigmine; Plasma Exchange; Thymectomy
PubMed: 6123843
DOI: No ID Found -
Acta Otorrinolaringologica Espanola 2000Myasthenia gravis is an illness of insidious onset whose first manifestation often is dysphagia. We report the case of a 25 year-old woman who consulted for nosebleed.... (Review)
Review
Myasthenia gravis is an illness of insidious onset whose first manifestation often is dysphagia. We report the case of a 25 year-old woman who consulted for nosebleed. On her first visit she referred progressive dysphagia, but the results of endoscopic digestive examination and indirect laryngoscopy were normal. The condition evolved until the appearance of weakness of the extremities suggested myasthenia. Myasthenia gravis was diagnosed by means of electromyography and determinations of antibodies against acetylcholine receptors. We reviewed the literature on the clinical manifestations, diagnostic procedures, and treatment of this condition. This case highlights the importance of suspecting myasthenia gravis in young women with dysphagia and a family or personal history of autoimmune disease in order to reach an early diagnosis and treatment.
Topics: Adult; Deglutition Disorders; Epistaxis; Female; Humans; Myasthenia Gravis; Nasal Septum; Ulcer
PubMed: 11142795
DOI: No ID Found -
Annual Review of Immunology 1985
Review
Topics: Animals; Autoantibodies; Disease Models, Animal; Humans; Lymphocytes; Myasthenia Gravis; Neuromuscular Junction; Receptors, Cholinergic; Synaptic Transmission; Syndrome
PubMed: 2998417
DOI: 10.1146/annurev.iy.03.040185.000545 -
The Journal of Neuropsychiatry and... 2000
Review
Topics: Acetylcholine; Case-Control Studies; Central Nervous System; Depression; Diagnosis, Differential; Evoked Potentials, Visual; Eye Movements; Female; Humans; Male; Myasthenia Gravis
PubMed: 11083171
DOI: 10.1176/jnp.12.4.514 -
The Journal of Pediatrics Feb 1986Signs of myasthenia gravis developed by age 3 years in 11 children. Six of these patients had persistent neonatal myasthenia gravis, a familial abnormality of...
Signs of myasthenia gravis developed by age 3 years in 11 children. Six of these patients had persistent neonatal myasthenia gravis, a familial abnormality of neuromuscular transmission that is not immunologically mediated. Five patients had juvenile onset myasthenia gravis, an autoimmune disorder similar to myasthenia gravis in adults. Autoimmune myasthenia has rarely been recognized by age 3 years, but the presence of five cases in our series suggests that the disorder may be more common in young children than once believed. The development of anti-acetylcholine receptor antibody assays makes it easier to distinguish autoimmune myasthenia gravis from the congenital forms. This distinction is important, because the prognosis, treatment, and risk of recurrence in family members is different for each type of myasthenia.
Topics: Antibodies; Autoimmune Diseases; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Myasthenia Gravis; Receptors, Cholinergic
PubMed: 3944702
DOI: 10.1016/s0022-3476(86)80981-7 -
Klinicheskaia Meditsina Sep 1973
Review
Topics: Cholinesterase Inhibitors; Electromyography; Eye Manifestations; Humans; Myasthenia Gravis; Prognosis; Respiratory Tract Diseases; Thymectomy; Thymus Gland
PubMed: 4598674
DOI: No ID Found -
Lancet (London, England) Sep 1969
Topics: Animals; Electric Stimulation; Electromyography; Female; Muscle Contraction; Myasthenia Gravis; Neuromuscular Junction; Thymus Gland; Tissue Extracts
PubMed: 4185607
DOI: 10.1016/s0140-6736(69)90342-0 -
Lancet (London, England) Jul 1969
Topics: Animals; Antigens; Autoimmune Diseases; Electromyography; Freund's Adjuvant; Guinea Pigs; Muscles; Myasthenia Gravis; Neostigmine; Synaptic Transmission; Thymus Gland
PubMed: 4182796
DOI: 10.1016/s0140-6736(69)92601-4 -
Annals of the New York Academy of... May 1998
Review
Topics: Adolescent; Child; Child, Preschool; Diagnostic Errors; Humans; Myasthenia Gravis; Remission, Spontaneous; Thymectomy
PubMed: 9668322
DOI: 10.1111/j.1749-6632.1998.tb11010.x -
Progress in Brain Research 1990
Review
Topics: Adrenal Cortex Hormones; Azathioprine; Cholinesterase Inhibitors; Humans; Myasthenia Gravis; Plasma Exchange; Thymectomy
PubMed: 2267293
DOI: 10.1016/s0079-6123(08)60899-7