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Lancet (London, England) Sep 1979Identification of a "cluster" of cases of acute myeloid leukaemia and chronic myeloproliferative disorders in Lytham St. Annes, Lancashire, prompted an analysis of the...
Identification of a "cluster" of cases of acute myeloid leukaemia and chronic myeloproliferative disorders in Lytham St. Annes, Lancashire, prompted an analysis of the incidence of myeloid leukaemias in Lancashire (excluding Ormskirk Health District), as recorded by the Manchester Cancer Registry. Although statistically there was no significant difference in the trend of incidence between the whole former borough of Lytham St. Annes and the other districts studied, the reported incidence of these diseases in the area as a whole had almost doubled, and in two districts nearly trebled, between two consecutive 6 year periods, beginning in 1965. This represents a substantially larger increase than mortality data suggests has occurred nationally in the same period, and is unlikely to be due solely to more accurate diagnosis or reporting.
Topics: England; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Space-Time Clustering
PubMed: 89557
DOI: 10.1016/s0140-6736(79)91613-1 -
Annales de Biologie Clinique 2014We report the case of a 20 years old woman with unusual acute myeloid leukemia t(8;21). Cytological, phenotypic and cytogenetic investigations showed a divergence from...
We report the case of a 20 years old woman with unusual acute myeloid leukemia t(8;21). Cytological, phenotypic and cytogenetic investigations showed a divergence from those of the literature as well as data for the last 12 LA to t(8;21) supported in the service.
Topics: Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Cytodiagnosis; Female; Humans; Immunophenotyping; Leukemia, Myeloid, Acute; Translocation, Genetic; Young Adult
PubMed: 24492100
DOI: 10.1684/abc.2013.0922 -
Blood Feb 2017
Topics: Adult; Diagnosis, Differential; Female; Humans; Leukemia, Myeloid, Acute; Sarcoma, Myeloid; Skin Neoplasms
PubMed: 28232624
DOI: 10.1182/blood-2016-10-743849 -
Journal of Clinical Oncology : Official... Mar 2014
Topics: Acute Disease; Antimetabolites, Antineoplastic; Cytarabine; Disease Progression; Dose Fractionation, Radiation; Fatal Outcome; Humans; Laryngeal Neoplasms; Leukemia, Myeloid, Acute; Male; Middle Aged; Neoplasm Recurrence, Local; Palliative Care; Respiratory Insufficiency; Sarcoma, Myeloid; Stem Cell Transplantation; Tomography, X-Ray Computed
PubMed: 24419134
DOI: 10.1200/JCO.2012.47.0047 -
Wiener Klinische Wochenschrift Dec 1972
Topics: Adult; Female; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Leukocyte Count; Middle Aged
PubMed: 4509036
DOI: No ID Found -
Haematologica Jan 2009The treatment of acute myeloid leukemia has improved in the last ten years, and in this perspective article Dr. Estey examines the recent progress in this field. See...
The treatment of acute myeloid leukemia has improved in the last ten years, and in this perspective article Dr. Estey examines the recent progress in this field. See related articles on pages 54 and 102.
Topics: Antineoplastic Agents; Cytogenetics; Hematopoietic Stem Cell Transplantation; Humans; Leukemia, Myeloid, Acute; Transplantation, Homologous; Treatment Outcome
PubMed: 19118375
DOI: 10.3324/haematol.2008.001263 -
Revue Medicale de Bruxelles 2013A pseudo-hyperkalemia may occur with hyperleukocytosis. It is important to recognize it early to avoid unnecessary or even dangerous treatment inducing hypokalemia. The...
A pseudo-hyperkalemia may occur with hyperleukocytosis. It is important to recognize it early to avoid unnecessary or even dangerous treatment inducing hypokalemia. The pseudohyperkalemia is due to cell fragility coupled to mechanical phenomena during blood collecting. We report a case of pseudo-hyperkalemia in a context of acute myeloid leukemia.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Etoposide; Female; Fluid Therapy; Humans; Hydroxyurea; Hyperkalemia; Leukemia, Myeloid, Acute; Leukocyte Count; Leukocytosis; Middle Aged; Treatment Outcome
PubMed: 23951858
DOI: No ID Found -
Expert Review of Vaccines Jul 2011
Topics: Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Treatment Outcome; Vaccines, DNA
PubMed: 21806391
DOI: 10.1586/erv.11.86 -
Hematological Oncology Mar 2012In this retrospective study, we aim to analyze the characteristics, treatments, and overall survival of all patients presenting with isolated myeloid sarcoma (MS) or MS...
In this retrospective study, we aim to analyze the characteristics, treatments, and overall survival of all patients presenting with isolated myeloid sarcoma (MS) or MS with concomitant acute myeloid leukemia (AML) compared with all patients with AML, treated during the same period. We identified patients with AML with or without MS at diagnosis, presenting to our medical center between the years 1990 and 2005. There was no statistically significant difference between the groups regarding gender, age, cytogenetic risk groups, rate of complete remission, number of cycles of chemotherapy needed to achieve complete remission, and rate of first relapse. The time to death in the MS group was not significantly different (p = 0.60) from the AML group, and radiotherapy did not affect the median time to death. Transplantation prolonged survival in both groups (p = 0.018 and p < 0.0001, respectively). Patients with MS at diagnosis might benefit from upfront aggressive treatment with hematopoietic stem cell transplantation.
Topics: Adult; Aged; Diagnosis, Differential; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Prognosis; Retrospective Studies; Sarcoma, Myeloid; Survival Analysis; Young Adult
PubMed: 21638303
DOI: 10.1002/hon.994 -
Cell Cycle (Georgetown, Tex.) May 2013
Topics: Animals; Humans; Leukemia, Myeloid, Acute; Myeloid-Lymphoid Leukemia Protein; Ubiquitin-Protein Ligases
PubMed: 23624838
DOI: 10.4161/cc.24748