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Indian Journal of Pathology &... 2010
Review
Topics: Humans; Leukemia, Myeloid; World Health Organization
PubMed: 20699489
DOI: 10.4103/0377-4929.68240 -
Texas Heart Institute Journal Dec 2016
Topics: Attitude of Health Personnel; Birth Certificates; Friends; Gift Giving; Humans; Leukemia, Myeloid, Acute; Oncologists; Physician-Patient Relations
PubMed: 28100963
DOI: 10.14503/THIJ-16-5913 -
[Rinsho Ketsueki] the Japanese Journal... Oct 2013
Review
Topics: Humans; Japan; Leukemia, Myeloid, Acute; Practice Guidelines as Topic; Prognosis; Recurrence; Risk Factors; World Health Organization
PubMed: 24064812
DOI: No ID Found -
JAMA Dec 2010
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Humans; Leukemia, Myeloid, Acute; Stem Cell Transplantation
PubMed: 21177513
DOI: 10.1001/jama.302.22.2759 -
Revista Brasileira de Pesquisas Medicas... 1974
Comparative Study
Topics: Aged; Autopsy; Bone Marrow; Diagnosis, Differential; Female; Humans; Leukemia, Myeloid; Leukocyte Count; Liver; Male; Middle Aged; Primary Myelofibrosis; Spleen; Uric Acid
PubMed: 4527643
DOI: No ID Found -
[Allogeneic bone marrow transplantation and myeloid leukemia in the chronic and accelerated stages].L'union Medicale Du Canada 1988
Review
Topics: Adult; Bone Marrow Transplantation; Female; Graft vs Host Disease; Humans; Leukemia, Myeloid; Leukemia, Myeloid, Acute; Male; Prognosis; Transplantation, Homologous
PubMed: 3041661
DOI: No ID Found -
Acta Haematologica 2018
Topics: Biomarkers, Tumor; Genetic Variation; Humans; Leukemia, Myeloid, Acute; Mutation; Prognosis; Recurrence
PubMed: 29444505
DOI: 10.1159/000487071 -
Terapevticheskii Arkhiv 1990
Review
Topics: Aged; Aging; Antineoplastic Combined Chemotherapy Protocols; Cell Transformation, Neoplastic; Hospitalization; Humans; Leukemia, Myeloid, Acute; Middle Aged; Remission Induction
PubMed: 2251656
DOI: No ID Found -
American Journal of Hematology Nov 2014
Topics: Aged, 80 and over; Basophils; Bone Marrow; Chromosome Aberrations; Diagnosis, Differential; Female; Humans; Leukemia, Basophilic, Acute; Leukemia, Myeloid, Acute; Megakaryocytes; Myelodysplastic Syndromes; Neoplastic Stem Cells
PubMed: 24941894
DOI: 10.1002/ajh.23789 -
Clinical Laboratory May 2024As a tumor mass, a myeloid sarcoma consists of myeloid blasts and presents at an anatomical site other than the bone marrow. In about one quarter of cases, myeloid...
BACKGROUND
As a tumor mass, a myeloid sarcoma consists of myeloid blasts and presents at an anatomical site other than the bone marrow. In about one quarter of cases, myeloid sarcoma happens without an underlying acute myeloid leukemia or other myeloid neoplasm, and it may precede or coincide with AML or form acute blastic transformation of MDSs, MPNs, or MDS/MPNs.
METHODS
Herein, we described a rare case of acute myeloid leukemia with myelodysplasia-related changes (AML-MRC), with WT1 mutation and high expression of TP53 after isolated myeloid sarcoma of lymph nodes showing a higher proportion of blasts, dysplasia of both megakaryocytes and granulocytes.
CONCLUSIONS
The case highlights the importance of a bone marrow examination, including morphology, immunophenotyping, cytogenetic, and molecular examination in all cases to exclude the possibility of myeloid sarcoma, especially the morphological feature of bone marrow dysplasia in the early stage before AML.
Topics: Humans; Sarcoma, Myeloid; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Mutation; Tumor Suppressor Protein p53; WT1 Proteins; Male; Bone Marrow; Middle Aged; Immunophenotyping
PubMed: 38747915
DOI: 10.7754/Clin.Lab.2023.231219