-
Clinical Case Reports Jul 2022This report details a retroperitoneal myxosarcoma in a cat that exhibited extremely aggressive biological behavior. An exploratory midline celiotomy revealed a...
This report details a retroperitoneal myxosarcoma in a cat that exhibited extremely aggressive biological behavior. An exploratory midline celiotomy revealed a left-sided retroperitoneal mass firmly adhered to the hypaxial musculature. Histopathological evaluation identified the mass as a myxosarcoma. Following surgical excision, the mass rapidly recurred within 6 weeks after surgery.
PubMed: 35846922
DOI: 10.1002/ccr3.6063 -
Caspian Journal of Internal Medicine Mar 2021It is a rare cardiac malignant primary tumor that seems to derive from the same cellular line as myxomas, but the prognosis is very different. It is a rare cardiac...
BACKGROUND
It is a rare cardiac malignant primary tumor that seems to derive from the same cellular line as myxomas, but the prognosis is very different. It is a rare cardiac malignant primary tumor that seems to derive from the same cellular line as myxomas, but the prognosis is very different. It is a rare cardiac malignant primary tumor that seems to derive from the same cellular line as myxomas, but the prognosis is very different. Cardiac myxosarcoma is a rare neoplasm that appears to rise from the same cellular source like myxoma. It is difficult to differentiate a myxoma tumor from a myxosarcoma tumor because of its appearance and pathology examination. Myxosercoma tumor requires surgery and chemoradiotherapy, but myxoma is treated only by surgery.
CASE PRESENTATION
We describe a case of a 58-year-old patient with a left atrium myxosarcoma, presenting with congestive heart failure. Transthoracic echocardiogram (TTE) showed a large polypoid and mobile mass in the left atrium, the patient underwent cardiac surgery and the tumor was successfully extracted, and histopathological result revealed typical features of myxoma. 15 days after surgery, he underwent explorative laparatomy because of progressive GI bleeding. Laparatomy revealed extensive metastatic masses in abdomen and the pathology diagnoses was myxosaroma. Unfortunately, in spite of supportive care, the patient expired on postoperative day one.
CONCLUSION
It is difficult to differentiate a myxoma tumor from a myxosarcoma tumor because of its appearance and pathology examination. Maybe magnetic resonance imaging can help us to achieve more data suggesting malignancy.
PubMed: 34012543
DOI: 10.22088/cjim.12.2.228 -
Veterinary Ophthalmology Sep 2003A male mixed breed dog of unknown age was presented with sudden onset of blindness and a slightly exophthalmic right eye. Ophthalmoscopically, a spherical, pinkish mass... (Review)
Review
A male mixed breed dog of unknown age was presented with sudden onset of blindness and a slightly exophthalmic right eye. Ophthalmoscopically, a spherical, pinkish mass protruding from the region of the optic disc into the vitreous was seen in the right eye. Ultrasound and computer tomography demonstrated an extension of the mass into the right retrobulbar space, continuing intracranially to the optic chiasm. Cytologic findings, obtained by ultrasound-guided fine needle aspiration from the retrobulbar space, were consistent with myxosarcoma. On the basis of these findings of a well-delineated mass in the brain stem area, irradiation was planned as the therapy of choice. The dog was treated under general anesthesia using a proton beam at the Paul Scherrer Institute (PSI, Villigen, Switzerland). A curative protocol (56 Gy in 16 fractions over 4 weeks, 3.5 Gy/fraction) was used. Twenty-seven days post radiation therapy the dog was euthanized, as clinical symptoms progressed. Enlargement of the intracranial tumor was seen on a CT study repeated on the day of euthanasia. A gross pathologic and histologic examination were performed and confirmed the diagnosis of a myxosarcoma involving the eye, retrobulbar space of the right side, and the optic chiasm. Post-mortem examination failed to identify any abnormalities or metastases elsewhere in the body.
Topics: Animals; Biopsy, Needle; Blindness; Brain Neoplasms; Diagnosis, Differential; Dog Diseases; Dogs; Eye Neoplasms; Male; Myxosarcoma; Tomography, X-Ray Computed; Ultrasonography
PubMed: 12950648
DOI: 10.1046/j.1463-5224.2003.00289.x -
Journal of the South African Veterinary... Jun 2023Myxosarcomas are rare malignant neoplasms of soft connective tissues, and there are no reports of hepatic myxosarcomas in cats. An eight-year-old male, neutered,...
Myxosarcomas are rare malignant neoplasms of soft connective tissues, and there are no reports of hepatic myxosarcomas in cats. An eight-year-old male, neutered, domestic shorthair cat presented with progressive hyporexia, lethargy, and weight loss. An ultrasonography study showed a large abdominal mass connected to the liver. The cat underwent a laparotomy and the mass was removed. Histopathological evaluation of the mass supported the diagnosis of a myxosarcoma. Tumour cells were positive with vimentin and alcian blue stain, and negative with PAS, pan-cytokeratin, s100, epithelial membrane antigen, and α-smooth muscle actin. The Ki-67 index by immunohistochemistry was 6%. The cat was euthanased due to severe lethargy and recumbency. Myxoid soft tissue neoplasms are very rare in cats, and to the best of our knowledge, this is the first report of a hepatic myxosarcoma in a cat. In the present case, the diagnosis was made based on histopathological and immunohistochemical findings and an alcian blue-positive supporting matrix.
PubMed: 37358322
DOI: 10.36303/JSAVA.537 -
Proceedings of the Royal Society of... Oct 1963
Topics: Diagnosis, Differential; Humans; Myxoma; Myxosarcoma; Neoplasms; Skin Neoplasms
PubMed: 14072145
DOI: No ID Found -
The Journal of Veterinary Medical... Apr 2021A 13-year-old intact Pomeranian bitch presented with a 2-month history of abdominal distension and anorexia. Ultrasonography and computed tomography revealed a large...
A 13-year-old intact Pomeranian bitch presented with a 2-month history of abdominal distension and anorexia. Ultrasonography and computed tomography revealed a large tumor in the abdominal cavity without metastases. The tumor was surgically resected and histopathologically characterized by spindle-shaped to atypical-shaped neoplastic cells with basophilic stroma in the omental adipose tissue. Immunohistochemistry revealed that the neoplastic cells were positive for vimentin but negative for cytokeratin, S-100 protein, and α-SMA. The bitch was diagnosed as a myxosarcoma arising from the greater omentum. Postoperatively, metronomic chemotherapy with cyclophosphamide and piroxicam was initiated. The tumor recurred on postoperative day 49. Although the bitch died 102 days after the initial examination, her general condition was maintained until death.
Topics: Adipose Tissue; Animals; Dog Diseases; Dogs; Female; Immunohistochemistry; Myxosarcoma; Neoplasm Recurrence, Local; Omentum
PubMed: 33504735
DOI: 10.1292/jvms.20-0509 -
Veterinary Clinical Pathology 1990
PubMed: 12684949
DOI: 10.1111/j.1939-165x.1990.tb00557.x -
Journal of the American Animal Hospital... 2020
Topics: Animals; Cat Diseases; Cats; Female; Kidney Neoplasms; Myxosarcoma
PubMed: 31961219
DOI: 10.5326/JAAHA-MS-6863 -
Archives of Dermatology and Syphilology Mar 1948
Topics: Humans; Myxosarcoma; Neoplasms
PubMed: 18098683
DOI: No ID Found -
Tierarztliche Praxis. Ausgabe K,... Feb 2023This case report describes a rare case of a myxosarcoma in a 1-year-old teddy bear hamster presenting with a mass in the cervical region. The fine-needle aspiration...
This case report describes a rare case of a myxosarcoma in a 1-year-old teddy bear hamster presenting with a mass in the cervical region. The fine-needle aspiration cytology revealed high numbers of pleomorphic spindle-shaped cells found in a viscous mucinous background. The presumptive cytological diagnosis was malignant spindle cell neoplasia based on marked criteria of malignancy of the mesenchymal cell population. The abundant matrix in the background was suggestive of a myxosarcoma. The hamster died during surgery and a necropsy was performed. Histopathology was in complete agreement with the cytological report. Immunohistochemistry revealed the tumour to be vimentin positive with alcian-blue positive matrix and confirmed the presumptive diagnosis of a myxosarcoma. This case shows that fine-needle aspiration cytology can be utilized as a minimally invasive diagnostic tool in small mammals to classify mass lesions. However, so far little is known about the biological behaviour of myxosarcoma in the hamster as case descriptions are rare.
Topics: Animals; Cricetinae; Myxosarcoma; Mesocricetus; Immunohistochemistry; Rodent Diseases
PubMed: 36917993
DOI: 10.1055/a-2009-9945