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International Journal of Environmental... Feb 2022Regional odontodysplasia is a rare developmental disorder characterised by hypoplasia and hypomineralisation of enamel and dentin. Our systematic review aimed to... (Review)
Review
Regional odontodysplasia is a rare developmental disorder characterised by hypoplasia and hypomineralisation of enamel and dentin. Our systematic review aimed to organise the knowledge on localisation, symptomatology and treatment methods in patients with regional odontodysplasia based on case reports published in the databases PubMed, Scopus and Web of Science. Case reports were described in 28 different countries, considering 180 patients (including 91 females). Regional odontodysplasia occurs mainly in both deciduous and permanent dentition (66.1%). The affected teeth were observed more frequently in the maxilla (70.0%), especially on the left side (45.6%). The most common reported symptoms were ghost teeth, poorly developed buds, yellowish-brown colour of crowns and delayed eruption of permanent teeth in affected quadrants. The most popular treatment method was surgical treatment (78.6%) with subsequent prosthetic therapy (34.6%). Based on the review of cases, pathognomonic clinical and radiological signs can be found, however, it is difficult to reach a consensus on the choice of treatment method.
Topics: Bibliometrics; Dentition, Permanent; Female; Humans; Maxilla; Odontodysplasia; Radiography; Tooth, Deciduous
PubMed: 35162705
DOI: 10.3390/ijerph19031683 -
The Saudi Dental Journal Jul 2019Regional odontodysplasia (RO) is a localized developmental anomaly involving both dentitions. The characteristic clinical findings are soft discolored several contiguous... (Review)
Review
BACKGROUND AND OBJECTIVE
Regional odontodysplasia (RO) is a localized developmental anomaly involving both dentitions. The characteristic clinical findings are soft discolored several contiguous teeth with atypical morphology associated with swelling or abscess formation. Radiographic images of the involved teeth show a ghost-like appearance because enamel and dentin are hypoplastic and hypocalcified. Although RO is known for more than seven decades, the literature on RO is mostly limited to case reports.The objective of this investigation was to provide an updated review of the literature with regards to clinical presentation and epidemiology of RO. Because of its rarity, retrospective analysis of the published reports across the world is considered one of the most appropriate available methods to analyze epidemiological and clinical data of RO. This review was reported and conducted according to the PRISMA guidelines.
RESULTS
Between 1953 and 2017, 161 cases were reported in literatures written in English. At the time of diagnosis, the age of the patients ranged between 1 and 25 years. There was slight female predilection with a ratio of 1.37: 1. When examined collectively, the maxilla was commonly affected compared to the mandible. RO occurred in both dentitions in 75 reported cases. While it affects the deciduous teeth alone in 19.3% and the permanent teeth in 34.2% of the cases. Failure of tooth eruption was the most common presenting finding (41.6%) followed by swelling of the affected area (32.3%).
CONCLUSION
Although RO was first described almost 80 years ago and the total subsequent case reports were over 160 cases, there is no consensus on its pathogenesis and how it should be treated. The descriptive nature of the examined case reports reveals the limited information on this condition. Further experimental and genetic studies are needed.
PubMed: 31337932
DOI: 10.1016/j.sdentj.2019.04.012 -
British Dental Journal Dec 1973
Topics: Child; Child, Preschool; Female; Humans; Male; Odontodysplasia; Radiography
PubMed: 4358870
DOI: 10.1038/sj.bdj.4803111 -
Oral Surgery, Oral Medicine, and Oral... Feb 1963
Topics: Humans; Odontodysplasia; Tooth
PubMed: 14003365
DOI: 10.1016/0030-4220(63)90031-8 -
Zhonghua Kou Qiang Yi Xue Za Zhi =... May 2024Regional odontodysplasia (ROD) is a rare localized dental developmental anomaly. The typical clinical manifestations of ROD are abnormal tooth eruption, abnormal... (Review)
Review
Regional odontodysplasia (ROD) is a rare localized dental developmental anomaly. The typical clinical manifestations of ROD are abnormal tooth eruption, abnormal development of enamel and dentin. The radiographic characteristic is "ghost teeth". Its etiology still remains unknown. The care and treatment of a patient with ROD needs a multidisciplinary approach. And the treatment should be taken after the assessment of each individual case of ROD. This paper reviews the definition, etiology, epidemiological features, clinical manifestations, imaging features, dental microstructure and treatment strategies of ROD to provide reference for clinical diagnosis and treatment.
Topics: Humans; Odontodysplasia; Dental Enamel; Dentin; Tooth Eruption
PubMed: 38637007
DOI: 10.3760/cma.j.cn112144-20240129-00043 -
Journal of Oral Pathology & Medicine :... May 1989Regional odontodysplasia is a localized disorder of tissues of dental origin resulting in characteristically bizarre clinical and radiographic appearances. It most... (Review)
Review
Regional odontodysplasia is a localized disorder of tissues of dental origin resulting in characteristically bizarre clinical and radiographic appearances. It most commonly affects the maxillary anterior teeth of both the permanent and primary dentitions. The authors present a worldwide bibliography of reported cases and discuss the suggested theories regarding the condition's etiology. Although the majority of cases of regional odontodysplasia must be regarded as idiopathic, various developmental anomalies may produce identical changes in the teeth in one or more quadrants. A number of previously reported cases are also reconsidered with regard to their diagnosis and guidelines are suggested for the treatment of patients affected by regional odontodysplasia.
Topics: Diagnosis, Differential; Humans; Odontodysplasia
PubMed: 2549236
DOI: 10.1111/j.1600-0714.1989.tb00394.x -
Journal of the American Dental... Nov 1975Results of a comprehensive dental examination, including a histologic evaluation, of a patient showing unilateral odontodysplasia revealed no hint as to the origin of...
Results of a comprehensive dental examination, including a histologic evaluation, of a patient showing unilateral odontodysplasia revealed no hint as to the origin of the abnormality. A complete medical examination also resulted in negative findings, with the excetion of congenital bilateral talipes equinovarus. The genetic history was negative, and results of chromosomal studies of the child and her mother revealed no abnormalities. Neither had an anatomic or a functional abnormality, with the exception of the odontodysplasia in the child. Results of laboratory studies including complete blood counts, urinalyses, ferric chloride tests of the urine, and electrolyte tests also were negative. The special considerations given in this case in an attempt to establish a possible causation of the abnormality were inconclusive. We think, however, that the management of the patient was successful in regard to the prosthetic appliance, and every attempt will be made to follow up the patient to ensure a good prognosis of the remaining developing dentition.
Topics: Denture, Partial, Removable; Female; Humans; Infant; Odontodysplasia; Radiography; Tooth, Deciduous
PubMed: 171293
DOI: 10.14219/jada.archive.1975.0520 -
Oral Surgery, Oral Medicine, and Oral... Jun 1970
Topics: Child, Preschool; Female; Humans; Tooth Abnormalities
PubMed: 5267631
DOI: 10.1016/0030-4220(70)90442-1 -
Journal of Dentistry For Children... Jan 2023Regional odontodysplasia (ROD) is a rare developmental anomaly with distinctive clinical, radiographical and histological findings, affecting both primary and permanent...
Regional odontodysplasia (ROD) is a rare developmental anomaly with distinctive clinical, radiographical and histological findings, affecting both primary and permanent dentitions. The teeth with ROD have an atypical morphology and are usually discolored, with either delayed eruption or complete failure to erupt. Radiographically, the affected teeth have a "ghostly" appearance, with marked radiolucency and decreased radiodensity, showing a thin outline of enamel and dentin, which appear hypomineralized histologically, with poorly structured dentinal tubules and enamel prisms. Calcifications are frequently found in the pulp chambers of the affected teeth. This case report discusses a three-year-old girl who presented with ROD in her mandible as well as the clinical and radiographical features, and treatment of the condition.
Topics: Humans; Female; Child, Preschool; Odontodysplasia; Dentition, Permanent; Tooth, Deciduous; Dental Enamel; Mandible
PubMed: 37106528
DOI: No ID Found -
Journal of the Indian Society of... 2011Regional odontodysplasia is an unusual developmental anomaly in which ectodermal and mesodermal tooth components are affected. We present a rare case of a developmental...
Regional odontodysplasia is an unusual developmental anomaly in which ectodermal and mesodermal tooth components are affected. We present a rare case of a developmental anomaly called regional odontodysplasia or 'ghost teeth' in a 12-year-old Indian girl. The anomaly affected right maxillary permanent teeth. The mandibular teeth were unaffected. The clinical, radiographic and histological features are reviewed. The management of affected patients is discussed.
Topics: Child; Female; Humans; Maxilla; Odontodysplasia; Radiography
PubMed: 22016318
DOI: 10.4103/0970-4388.86380