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Le Infezioni in Medicina 2016Oligella ureolytica is an emerging bacteria rarely implicated as a human pathogen. It is mostly recovered from urinary and respiratory tract specimens as a commensal... (Review)
Review
Oligella ureolytica is an emerging bacteria rarely implicated as a human pathogen. It is mostly recovered from urinary and respiratory tract specimens as a commensal organism, but very seldom from bloodstream infections. It is rarely reported in the literature, probably due to misidentification of the organism or uncertainty of its pathogenicity.
Topics: Aged; Alcaligenaceae; Anti-Bacterial Agents; Aortic Valve Stenosis; Bacteremia; Drug Therapy, Combination; Gram-Negative Bacterial Infections; Humans; Male; Penicillanic Acid; Piperacillin; Risk Factors; Tazobactam; Treatment Outcome
PubMed: 27031899
DOI: No ID Found -
Journal of Infection in Developing... Jun 2014Oligella species are small, Gram-negative, nonsaccharolytic aerobic rods or coccobacilli that are catalase and oxidase-positive, mostly isolated from the urinary tract... (Review)
Review
Oligella species are small, Gram-negative, nonsaccharolytic aerobic rods or coccobacilli that are catalase and oxidase-positive, mostly isolated from the urinary tract and rarely from wounds, bloodstream infections, septic arthritis, or peritonitis.In this article, we report a case of O.ureolytica-related bloodstream infection in a newborn infant and we review the literature for previously reported cases of Oligella infections.
Topics: Alcaligenaceae; Anti-Bacterial Agents; Bacteremia; Developing Countries; Female; Gram-Negative Bacterial Infections; Humans; Infant, Newborn; Microbial Sensitivity Tests; Netilmicin; Turkey
PubMed: 24916881
DOI: 10.3855/jidc.3260 -
Indian Journal of Pathology &... 2014Oligella ureolytica is an emerging bacteria rarely implicated as a human pathogen. It is infrequently recovered from clinical specimens probably because of inadequate... (Review)
Review
Oligella ureolytica is an emerging bacteria rarely implicated as a human pathogen. It is infrequently recovered from clinical specimens probably because of inadequate processing of non-fermenting oxidase positive Gram negative bacilli. We present here a case of a 30 year old male suffering from right lung adenocarcinoma (moderately differentiated) with multiple abdominal lymph node metastasis with Syringohydromyelia whose blood culture yielded Oligella ureolytica in pure culture. Oligella ureolytica isolation in pure culture and the patient's response to targeted treatment supported that Oligella ureolytica was the true causative agent of the blood stream infection. Early suspicion, diagnosis and treatment with potent antibiotics are needed to prevent further complications resulting from infection with this emerging pathogen.
Topics: Adenocarcinoma; Adult; Alcaligenaceae; Anti-Bacterial Agents; Bacteremia; Gram-Negative Bacterial Infections; Humans; Lung Neoplasms; Male; Treatment Outcome
PubMed: 24739856
DOI: 10.4103/0377-4929.130928 -
Emerging Infectious Diseases Jul 2015
Topics: Aged; Alcaligenaceae; Bacteremia; Female; Gram-Negative Bacterial Infections; Humans; United States
PubMed: 26079071
DOI: 10.3201/eid2107.150242 -
Antibiotics (Basel, Switzerland) Sep 2023is a Gram-negative bacillus, a member of the family, that had never previously been reported as lethal. Herein, a case of fatal infection caused by in an elderly...
is a Gram-negative bacillus, a member of the family, that had never previously been reported as lethal. Herein, a case of fatal infection caused by in an elderly woman with suspected bladder cancer is reported. The species identification was confirmed through Sanger sequencing of the bacterial 16S rRNA sequence and compared to published sequences for phylogenetic analysis. Initial antibiotic therapy with ceftriaxone and oxacillin was initiated but had to be switched due to resistance. Cefepime in combination with metronidazole was administered, unfortunately failing to prevent the patient's death. Further studies are needed to explore additional factors influencing clinical outcomes in infections.
PubMed: 37760766
DOI: 10.3390/antibiotics12091470 -
European Journal of Clinical... Apr 2024Oligella is an uncommon Gram-negative coccobacillus that was first thought to belong to the urogenital tract. The genus Oligella comprises two species that were... (Review)
Review
BACKGROUND
Oligella is an uncommon Gram-negative coccobacillus that was first thought to belong to the urogenital tract. The genus Oligella comprises two species that were recovered from various samples worldwide.
METHODS
We perform a systematic review focusing on Oligella microbiological characteristics, habitat, role in Human microbiome and infection, and antimicrobial susceptibility.
RESULTS
In humans, Oligella is mainly found as part of the microbiome of individuals with predisposing conditions. Oligella were also associated with invasive infections in patients with underlying diseases. Nevertheless, their prevalence remains to determine. Oligella culture requires up to 48 h on agar media in vitro, while urinary samples are usually incubated for 24 h. Consequently, microbiologists should be prompt to prolong the incubation of agar media when the direct examination showed Gram-negative coccobacilli. Oligella is accurately identified using MALDI-TOF mass spectrometry, but biochemical methods often provided inconsistent results. Specific guidelines for antimicrobial susceptibility testing of Oligella lack but the incubation could require up to 48 h of incubation. In contrast to O. urethralis, which is susceptible to third-generation cephalosporin, O. ureolytica is likely resistant to numerous antimicrobials. Genectic determinants of resistance were identified for beta-lactams and aminoglycosides.
CONCLUSION
Oligella is an uncommon pathogen that can be underrecognized. Microbiologists should be prompt to prolong the incubation of agar media plated with urines when the direct examination showed Gram-negative coccobacilli. Carbapenems should probably be given for the empirical treatment.
PubMed: 38668878
DOI: 10.1007/s10096-024-04797-9 -
European Journal of Clinical... Feb 2001
Topics: Anti-Bacterial Agents; Azithromycin; Ceftriaxone; Cefuroxime; Cephalosporins; Gram-Negative Anaerobic Bacteria; Gram-Negative Bacterial Infections; Humans; Infant; Male; Pneumonia
PubMed: 11305472
DOI: 10.1007/pl00011246 -
Cureus Feb 2023is a commensal bacteria genus of the human urinary tract that rarely precipitates clinical infections. We report the case of an asymptomatic 24-year-old male with a...
is a commensal bacteria genus of the human urinary tract that rarely precipitates clinical infections. We report the case of an asymptomatic 24-year-old male with a medical history of Tourette syndrome and the recent placement of deep brain stimulator leads, which were found to be co-infected with species during hardware implantation. This is the first reported case of a deep brain stimulator infection by , a potentially under-recognized and emerging opportunistic bacteria. We review the previously published cases of extra-genitourinary infections and detail the clinical management of this uncommon pathogen.
PubMed: 36949980
DOI: 10.7759/cureus.35133 -
Clinical Infectious Diseases : An... Aug 1993
Topics: AIDS-Related Opportunistic Infections; Adult; Bacteremia; Bacteroides Infections; Candidiasis; Fungemia; Gram-Negative Aerobic Bacteria; Gram-Negative Bacterial Infections; Humans; Male
PubMed: 8399890
DOI: 10.1093/clinids/17.2.290 -
GMS Hygiene and Infection Control 2019To quantify the frequency of bacterial contamination of the injected contrast agent/saline solution by an automated contrast injection system, and to evaluate whether...
To quantify the frequency of bacterial contamination of the injected contrast agent/saline solution by an automated contrast injection system, and to evaluate whether usage of a novel tube system can reduce it. For bacterial contamination quantification two identical automated piston pump MRI contrast injectors were used in combination with a standard tube system. 3-5 ml of the contrast agent/saline solution was collected from the system prior to its connection to the patients' venous cannula in 104 consecutive patients. To test, whether a novel tube system reduces contamination, a tube system with shielded screw connections was used with the same contrast injectors and contrast agent/saline samples were collected in further 101 patients. Specimens were microbiologically analyzed. Frequencies of contamination were compared using Fisher exact test. With the standard tube system, bacterial contamination was observed in 5.8% (6 out of 104 specimens). With the novel tube system, contamination was observed in 2.0% (2 out of 101 specimens, p=0.280). was the most common germ (5 cases) followed by (2 cases) and (1 case). Bacterial contaminations of MRI contrast injectors occurred in a non-negligible frequency especially with . A trend towards reduced bacterial contamination was seen when a novel tube system with shielded screw connections was used.
PubMed: 31198659
DOI: 10.3205/dgkh000321