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Deutsche Zahn-, Mund-, Und... Mar 1974
Review
Topics: Biology; Dental Care; Diagnosis, Oral; Humans; Mouth; Pathology, Oral; Periodontal Diseases
PubMed: 4597228
DOI: No ID Found -
Computer Methods in Biomechanics and... Aug 2010
Topics: Biomechanical Phenomena; Humans; Larynx; Models, Anatomic; Mouth; Pharynx
PubMed: 20635260
DOI: 10.1080/10255842.2010.501146 -
Advanced Drug Delivery Reviews Mar 2004The delivery of therapeutic agents to, or via, the oral cavity is limited by the efficient removal mechanisms that exist in this area. Lectins are proteins or... (Review)
Review
The delivery of therapeutic agents to, or via, the oral cavity is limited by the efficient removal mechanisms that exist in this area. Lectins are proteins or glycoproteins that bind to specific sugar residues, and can, therefore, interact with the glycoconjugates present on cell surfaces or salivary mucins. Endogenous lectins could also be used as points of attachment for carbohydrate-containing delivery systems. This review considers the possibility of using lectins as targeting agents within the oral cavity and reports on some of the limited number of studies completed to date. As lectins are multifunctional molecules, the possibility of using them as both targeting and therapeutic agents is considered. Lectin-containing delivery systems are a potential innovation for targeted and prolonged therapy within the oral cavity, but considerations such as toxicity and cost will need to be addressed before their routine use becomes a reality.
Topics: Administration, Oral; Animals; Drug Delivery Systems; Humans; Lectins; Mouth; Mouth Diseases
PubMed: 14969754
DOI: 10.1016/j.addr.2003.10.016 -
Journal of Oral Science 2017Rehabilitation for dysfunctions of eating and swallowing should be considered in terms of not only motor but also sensory function. Sensory information from a bolus in...
Rehabilitation for dysfunctions of eating and swallowing should be considered in terms of not only motor but also sensory function. Sensory information from a bolus in the mouth plays an important role in eating and swallowing. Therefore, this study investigated oral stereognosis in 184 healthy adults with normal eating and swallowing function in order to obtain normative data. Oral stereognosis was assessed by using 20 intra-oral test pieces with different shapes. The subjects manipulated the test pieces in the mouth and identified their shapes. At this time, the test scores and response times for answering were recorded. The results revealed differences in oral stereognosis depending on the age of the subjects and the test pieces employed. The younger group had higher test scores and shorter response times than the older group, except for comparisons between the 20s and 30s age groups. In addition, response time was negative correlated with test scores (r = -0.956, P < 0.001). These results indicate that oral stereognosis decreases with age.
Topics: Adult; Female; Humans; Male; Mouth; Stereognosis; Tongue; Young Adult
PubMed: 28367901
DOI: 10.2334/josnusd.16-0366 -
Advances in Applied Microbiology 2008
Review
Topics: Anti-Infective Agents; Antimicrobial Cationic Peptides; Host-Pathogen Interactions; Humans; Mouth; Mouth Diseases
PubMed: 18395131
DOI: 10.1016/S0065-2164(07)00008-1 -
Periodontology 2000 Feb 2016Over the last 10 years there have been only a handful of publications dealing with the oral virome, which is in contrast to the oral microbiome, an area that has seen... (Review)
Review
Over the last 10 years there have been only a handful of publications dealing with the oral virome, which is in contrast to the oral microbiome, an area that has seen considerable interest. Here, we survey viral infections in general and then focus on those viruses that are found in and/or are transmitted via the oral cavity; norovirus, rabies, human papillomavirus, Epstein-Barr virus, herpes simplex viruses, hepatitis C virus, and HIV. Increasingly, viral infections have been diagnosed using an oral sample (e.g. saliva mucosal transudate or an oral swab) instead of blood or urine. The results of two studies using a rapid and semi-quantitative lateral flow assay format demonstrating the correlation of HIV anti-IgG/sIgA detection with saliva and serum samples are presented. When immediate detection of infection is important, point-of-care devices that obtain a non-invasive sample from the oral cavity can be used to provide a first line diagnosis to assist in determining appropriate counselling and therapeutic path for an increasing number of diseases.
Topics: Humans; Mouth; Saliva; Virus Diseases
PubMed: 26662485
DOI: 10.1111/prd.12112 -
Ear, Nose, & Throat Journal May 1990Signs and local symptoms of leukemia in the oral cavity include paleness of the oral mucosa with gingival bleeding that develops into painless gingival hyperplasia,...
Signs and local symptoms of leukemia in the oral cavity include paleness of the oral mucosa with gingival bleeding that develops into painless gingival hyperplasia, hemorrhages, and ulcerative necrotic lesions. These findings are common clinical manifestations of leukemias and frequently herald the onset of the disease. Because of their clinical importance, all such lesions deserve the full attention of dentists and physicians.
Topics: Adolescent; Adult; Female; Gingiva; Humans; Labial Frenum; Leukemia; Male; Middle Aged; Mouth; Mouth Diseases; Mouth Mucosa; Palate
PubMed: 2379479
DOI: No ID Found -
Ear, Nose, & Throat Journal Aug 1978
Topics: Humans; Mouth; Mouth Mucosa; Stomatitis
PubMed: 699818
DOI: No ID Found -
The Compendium of Continuing Education... 1983
Topics: Cryosurgery; Humans; Mouth; Mouth Diseases
PubMed: 6583047
DOI: No ID Found -
Northwest Dentistry Oct 1947
Topics: Diagnosis, Oral; Humans; Mouth
PubMed: 18907823
DOI: No ID Found